GluN2A mediates ketamine-induced rapid antidepressant-like responses
暂无分享,去创建一个
Yelin Chen | Yang Geng | Tonghui Su | Chaoying Fu | Yi Lu | Yang Geng
[1] J. Kaminker,et al. NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury. , 2022, Cell reports.
[2] J. Radulovic,et al. GluN2A-ERK-mTOR pathway confers a vulnerability to LPS-induced depressive-like behaviour , 2021, Behavioural Brain Research.
[3] C. Zarate,et al. Novel Glutamatergic Modulators for the Treatment of Mood Disorders: Current Status , 2021, CNS Drugs.
[4] J. Lacaille,et al. Antidepressant actions of ketamine engage cell-specific translation via eIF4E , 2020, Nature.
[5] D. Johnston,et al. Antidepressant Effects of (S)-Ketamine through a Reduction of Hyperpolarization-Activated Current Ih , 2020, iScience.
[6] K. Behar,et al. Cell-type specific modulation of NMDA receptors triggers antidepressant actions , 2020, Molecular Psychiatry.
[7] S. Wilkinson,et al. A new generation of antidepressants: an update on the pharmaceutical pipeline for novel and rapid-acting therapeutics in mood disorders based on glutamate/GABA neurotransmitter systems. , 2019, Drug discovery today.
[8] J. Nyengaard,et al. Neurite atrophy in dorsal hippocampus of rat indicates incomplete recovery of chronic mild stress induced depression , 2019, NMR in biomedicine.
[9] N. Picard,et al. NMDA 2A receptors in parvalbumin cells mediate sex-specific rapid ketamine response on cortical activity , 2019, Molecular Psychiatry.
[10] T. Gould,et al. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms , 2018, Pharmacological Reviews.
[11] R. Duman. Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide , 2018, F1000Research.
[12] L. McMahon,et al. Disinhibition of CA1 pyramidal cells by low-dose ketamine and other antagonists with rapid antidepressant efficacy , 2018, Proceedings of the National Academy of Sciences.
[13] N. Tamamaki,et al. Inhibitory neuron‐specific Cre‐dependent red fluorescent labeling using VGAT BAC‐based transgenic mouse lines with identified transgene integration sites , 2018, The Journal of comparative neurology.
[14] Hailan Hu,et al. Ketamine blocks bursting in the lateral habenula to rapidly relieve depression , 2018, Nature.
[15] Hailan Hu,et al. Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression , 2018, Nature.
[16] D. Inta,et al. Molecular and cellular dissection of NMDA receptor subtypes as antidepressant targets , 2018, Neuroscience & Biobehavioral Reviews.
[17] Qiye He,et al. Use of TAI-FISH to visualize neural ensembles activated by multiple stimuli , 2017, Nature Protocols.
[18] Guoqiang Hou,et al. NMDA Receptors Regulate the Development of Neuronal Intrinsic Excitability through Cell-Autonomous Mechanisms , 2017, Front. Cell. Neurosci..
[19] J. Sato,et al. The Nucleus Accumbens and Ketamine Treatment in Major Depressive Disorder , 2017, Neuropsychopharmacology.
[20] Kyle A. Lyman,et al. HCN channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects , 2016, Molecular Psychiatry.
[21] Xi-Ping Huang,et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites , 2016, Nature.
[22] W. Lu,et al. An NMDA Receptor-Dependent Mechanism Underlies Inhibitory Synapse Development. , 2016, Cell reports.
[23] K. Jiao,et al. Correlation of functional GRIN2A gene promoter polymorphisms with schizophrenia and serum D-serine levels. , 2015, Gene.
[24] K. Nakazawa,et al. NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism , 2015, Behavioural Brain Research.
[25] Michele Pignatelli,et al. Engram cells retain memory under retrograde amnesia , 2015, Science.
[26] K. Deisseroth,et al. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression , 2015, Nature Communications.
[27] Rachel S White,et al. Pyramidal Cell Selective Ablation of N-Methyl-D-Aspartate Receptor 1 Causes Increase in Cellular and Network Excitability , 2015, Biological Psychiatry.
[28] Y. Auberson,et al. The Role of GluN2A and GluN2B Subunits on the Effects of NMDA Receptor Antagonists in Modeling Schizophrenia and Treating Refractory Depression , 2014, Neuropsychopharmacology.
[29] J. Kaminker,et al. Activity-Induced Nr4a1 Regulates Spine Density and Distribution Pattern of Excitatory Synapses in Pyramidal Neurons , 2014, Neuron.
[30] E. Nestler,et al. The brain reward circuitry in mood disorders , 2013, Nature Reviews Neuroscience.
[31] Qiang Zhou,et al. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease , 2013, Nature Reviews Neuroscience.
[32] Mark Ellisman,et al. The Cell-Autonomous Role of Excitatory Synaptic Transmission in the Regulation of Neuronal Structure and Function , 2013, Neuron.
[33] S. Chaki,et al. Role of BDNF/TrkB signaling in antidepressant-like effects of a group II metabotropic glutamate receptor antagonist in animal models of depression , 2013, Behavioural Brain Research.
[34] Daisuke Kase,et al. The Role of HCN Channels on Membrane Excitability in the Nervous System , 2012, Journal of signal transduction.
[35] D. Johnston,et al. Enhancement of Dorsal Hippocampal Activity by Knockdown of HCN1 Channels Leads to Anxiolytic- and Antidepressant-like Behaviors , 2012, Neuron.
[36] D. Malone,et al. Consequences of early life MK-801 administration: Long-term behavioural effects and relevance to schizophrenia research , 2012, Behavioural Brain Research.
[37] Linh Vong,et al. Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons , 2011, Neuron.
[38] E. Kavalali,et al. NMDA Receptor Blockade at Rest Triggers Rapid Behavioural Antidepressant Responses , 2011, Nature.
[39] Nanxin Li,et al. mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists , 2010, Science.
[40] Allan R. Jones,et al. A robust and high-throughput Cre reporting and characterization system for the whole mouse brain , 2009, Nature Neuroscience.
[41] Naoshige Uchida,et al. A Defined Network of Fast-Spiking Interneurons in Orbitofrontal Cortex: Responses to Behavioral Contingencies and Ketamine Administration , 2009, Front. Syst. Neurosci..
[42] J. Mann,et al. Early evidence on the effects of regulators' suicidality warnings on SSRI prescriptions and suicide in children and adolescents. , 2007, The American journal of psychiatry.
[43] A. Bhandoola,et al. Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. , 2007, Cell stem cell.
[44] O. Hermanson,et al. Genetic targeting of principal neurons in neocortex and hippocampus of NEX‐Cre mice , 2006, Genesis.
[45] D. Wyllie,et al. Equilibrium Constants for (R)-[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic Acid (NVP-AAM077) Acting at Recombinant NR1/NR2A and NR1/NR2B N-Methyl-d-aspartate Receptors: Implications for Studies of Synaptic Transmission , 2006, Molecular Pharmacology.
[46] A. Holmes,et al. Genetic Inactivation of the NMDA Receptor NR2A Subunit has Anxiolytic- and Antidepressant-Like Effects in Mice , 2006, Neuropsychopharmacology.
[47] V. Murthy,et al. Multiple forms of synaptic plasticity triggered by selective suppression of activity in individual neurons , 2002, Nature.
[48] M. Fava,et al. Timing of onset of antidepressant response with fluoxetine treatment. , 2000, The American journal of psychiatry.
[49] D. Kernell,et al. Input Resistance, Electrical Excitability, and Size of Ventral Horn Cells in Cat Spinal Cord , 1966, Science.