Parametric Amplification of Magnetic Resonance Images

Parametric amplification is considered as a method for the detection of magnetic resonance imaging (MRI) signals. The theory of three-frequency amplifiers is reviewed, and aspects relevant to radio-frequency detection are highlighted. The modifications needed for MRI are described, and a parametrically amplified surface coil for 63.85 MHz operation is demonstrated. Electrical characterization is carried out, and good agreement is obtained with the theory. A linear gain of 100 (40 dB power gain) and a Q-factor of 18 000 are demonstrated. 1H MRI is carried out at 1.5 T and frequency-domain filtering of images is demonstrated.

[1]  C. S. Aitchison,et al.  Hybrid parametric amplifier at 30 MHz with a noise temperature of 18 K , 1976 .

[2]  L. Dickens A millimeter-wave pumped X-band uncooled parametric amplifier , 1972 .

[3]  E. W. Sard,et al.  Analysis of a Negative Conductance Amplifier Operated with a Nonideal Circulator , 1959 .

[4]  B. J. Robinson Theory of variable-capacitance parametric amplifiers , 1962 .

[5]  J.-P. Raskin,et al.  A novel parametric-effect MEMS amplifier , 2000, Journal of Microelectromechanical Systems.

[6]  M. J. Thompson,et al.  Parametrically Amplified $Z$-Axis Lorentz Force Magnetometer , 2011, Journal of Microelectromechanical Systems.

[7]  G. L. Matthaei,et al.  A Study of the Optimum Design of Wide-Band Parametric Amplifiers and Up-Converters , 1961 .

[8]  J. Dejager Maximum Bandwidth Performance of Non- degenerate Parametric Amplifier with Single-Tuned Idler Circuit , 1964 .

[9]  M. Fukada,et al.  Optimum Synthesis of Wide-Band Parametric Amplifiers and Converters , 1961 .

[10]  J. Garbini,et al.  Detection of AC magnetic signals by parametric mode coupling in a mechanical oscillator , 1996 .

[11]  Robert L. Byer,et al.  Optical parametric amplification , 1979 .

[12]  G. Wade,et al.  Gain, Band Width, and Noise Characteristics of the Variable‐Parameter Amplifier , 1958 .

[13]  T. Hollocher,et al.  USE OF A PARAMETRIC AMPLIFIER IN ELECTRON SPIN RESONANCE SPECTROMETER DESIGN. , 1964, Physics in medicine and biology.

[14]  D. Rugar,et al.  Mechanical parametric amplification and thermomechanical noise squeezing. , 1991, Physical review letters.

[15]  A. Šantić Low-Frequency Parametric Amplifier for Small Voltage Measurements , 1974 .

[16]  W. G. Matthei,et al.  Experimental Verification of the Phase Relationships in Parametric Amplifiers (Correspondence) , 1964 .

[17]  C. S. Aitchison,et al.  The overall noise figures of diode parametric amplifier systems , 1963 .

[18]  G N Holland,et al.  An overview of digital spectrometers for MR imaging , 1992, Journal of magnetic resonance imaging : JMRI.

[19]  P. Lauterbur,et al.  The sensitivity of the zeugmatographic experiment involving human samples , 1979 .

[20]  W. P. Connors Maximally Flat Bandwidth of Nondegenerate Parametric Amplifier with Double Tuned Signal Circuit and Single Tuned Idler Circuit (Correspondence) , 1965 .

[21]  W. W. Mumford,et al.  Some Notes on the History of Parametric Transducers , 1960, Proceedings of the IRE.

[22]  Kurt Garbrecht Noise limitation in helium-cooled parametric amplifiers , 1966 .

[23]  Zhongxu Hu,et al.  A parametrically amplified MEMS rate gyroscope , 2011 .

[24]  F David Doty,et al.  Radio frequency coil technology for small‐animal MRI , 2007, NMR in biomedicine.

[25]  H. Rowe,et al.  Some General Properties of Nonlinear Elements-Part I. General Energy Relations , 1956, Proceedings of the IRE.

[26]  A. Van Der Ziel,et al.  On the Mixing Properties of Non‐Linear Condensers , 1948 .

[27]  I. R. Young,et al.  Three-frequency parametric amplification in magneto-inductive ring resonators , 2008 .

[28]  E.D. Reed,et al.  The variable-capacitance parametric amplifier , 1959, IRE Transactions on Electron Devices.

[29]  Observation of 4.2-K equilibrium-noise squeezing via a Josephson-parametric amplifier. , 1989, Physical review letters.

[30]  Peter A. Andrekson,et al.  Fiber-based optical parametric amplifiers and their applications , 2002 .

[31]  C. S. Aitchison,et al.  for Use at S, C, and X Band , 1967 .

[32]  F. David Doty,et al.  RF Coil Technology for Small-Animal MRI , 2007 .

[33]  F. J. Hyde,et al.  Two-diode bandpass parametric amplifier , 1967 .

[34]  S. Arridge,et al.  Sources of intensity nonuniformity in spin echo images at 1.5 T , 1994, Magnetic resonance in medicine.

[35]  L Axel,et al.  Noise performance of surface coils for magnetic resonance imaging at 1.5 T. , 1985, Medical physics.