Personalized Network‐Based Treatments in Oncology
暂无分享,去创建一个
R. Linding | J. Longden | O. Radetskaya | CC Santini | Xavier Arnaud Robin | Pau Creixell | X. Robin | O. Radetskaya | Cristina Costa Santini
[1] U. Nielsen,et al. Computational Modeling of ERBB2-Amplified Breast Cancer Identifies Combined ErbB2/3 Blockade as Superior to the Combination of MEK and AKT Inhibitors , 2013, Science Signaling.
[2] F. Nicolantonio,et al. Liquid biopsy: monitoring cancer-genetics in the blood , 2013, Nature Reviews Clinical Oncology.
[3] Jorge S. Reis-Filho,et al. Circulating tumour cells and cell-free DNA as tools for managing breast cancer , 2013, Nature Reviews Clinical Oncology.
[4] Krishnendu Chatterjee,et al. Evolutionary dynamics of cancer in response to targeted combination therapy , 2013, eLife.
[5] Tian Xia,et al. Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo. , 2013, ACS nano.
[6] Rune Linding,et al. Navigating cancer network attractors for tumor-specific therapy , 2012, Nature Biotechnology.
[7] Karen Sachs,et al. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators , 2012, Nature Biotechnology.
[8] Liang Liu,et al. Network-based drug discovery by integrating systems biology and computational technologies , 2012, Briefings Bioinform..
[9] B. Al-Lazikani,et al. Combinatorial drug therapy for cancer in the post-genomic era , 2012, Nature Biotechnology.
[10] H. Hieronymus,et al. Traversing the genomic landscape of prostate cancer from diagnosis to death , 2012, Nature Genetics.
[11] R. Linding,et al. Network Medicine Strikes a Blow against Breast Cancer , 2012, Cell.
[12] P. Sorger,et al. Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks , 2012, Cell.
[13] A. Kesselheim,et al. The Prevalence and Cost of Unapproved Uses of Top-Selling Orphan Drugs , 2012, PloS one.
[14] J. Burnett,et al. RNA-based therapeutics: current progress and future prospects. , 2012, Chemistry & biology.
[15] Jörn Lötsch,et al. Low-dose drug combinations along molecular pathways could maximize therapeutic effectiveness while minimizing collateral adverse effects. , 2011, Drug discovery today.
[16] Mindy I. Davis,et al. Comprehensive analysis of kinase inhibitor selectivity , 2011, Nature Biotechnology.
[17] Theonie Anastassiadis,et al. Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity , 2011, Nature Biotechnology.
[18] Bissan Al-Lazikani,et al. canSAR: an integrated cancer public translational research and drug discovery resource , 2011, Nucleic Acids Res..
[19] John P. Overington,et al. ChEMBL: a large-scale bioactivity database for drug discovery , 2011, Nucleic Acids Res..
[20] Jorge S Reis-Filho,et al. Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction , 2011, Breast Cancer Research.
[21] Michael R Stratton,et al. Genomics and the continuum of cancer care. , 2011, The New England journal of medicine.
[22] David S. Wishart,et al. DrugBank 3.0: a comprehensive resource for ‘Omics’ research on drugs , 2010, Nucleic Acids Res..
[23] Brian D Ross,et al. Predicting and monitoring cancer treatment response with diffusion‐weighted MRI , 2010, Journal of magnetic resonance imaging : JMRI.
[24] G. Mills,et al. Future of personalized medicine in oncology: a systems biology approach. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] R. Linding,et al. Simplistic pathways or complex networks? , 2010, Current opinion in genetics & development.
[26] Jorge S Reis-Filho,et al. The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade , 2010, The Journal of pathology.
[27] R. Linding,et al. Network‐based drugs and biomarkers , 2010, The Journal of pathology.
[28] Tony Pawson,et al. Cell-Specific Information Processing in Segregating Populations of Eph Receptor Ephrin–Expressing Cells , 2009, Science.
[29] Andrew L. Hopkins,et al. Drug discovery: Predicting promiscuity , 2009, Nature.
[30] Forest M White,et al. Oncogenic EGFR Signaling Networks in Glioma , 2009, Science Signaling.
[31] V. Grantcharova,et al. Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB Receptor–PI3K Axis , 2009, Science Signaling.
[32] Michael J. Emanuele,et al. A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene , 2009, Cell.
[33] Norbert Avril,et al. Response to Therapy in Breast Cancer , 2009, Journal of Nuclear Medicine.
[34] Angelo D. Favia,et al. Protein promiscuity and its implications for biotechnology , 2009, Nature Biotechnology.
[35] Daniel G. Anderson,et al. Knocking down barriers: advances in siRNA delivery , 2009, Nature Reviews Drug Discovery.
[36] A. Hopkins. Network pharmacology: the next paradigm in drug discovery. , 2008, Nature chemical biology.
[37] C. Bakal,et al. Phosphorylation Networks Regulating JNK Activity in Diverse Genetic Backgrounds , 2008, Science.
[38] R. Bernards,et al. Enabling personalized cancer medicine through analysis of gene-expression patterns , 2008, Nature.
[39] Forest M White,et al. Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma , 2007, Proceedings of the National Academy of Sciences.
[40] A. Barabasi,et al. Network medicine--from obesity to the "diseasome". , 2007, The New England journal of medicine.
[41] P. Bork,et al. Systematic Discovery of In Vivo Phosphorylation Networks , 2007, Cell.
[42] C. Bakal,et al. Quantitative Morphological Signatures Define Local Signaling Networks Regulating Cell Morphology , 2007, Science.
[43] John P. Overington,et al. How many drug targets are there? , 2006, Nature Reviews Drug Discovery.
[44] G. V. Paolini,et al. Global mapping of pharmacological space , 2006, Nature Biotechnology.
[45] John P. Overington,et al. Can we rationally design promiscuous drugs? , 2006, Current opinion in structural biology.
[46] D. Lauffenburger,et al. A Systems Model of Signaling Identifies a Molecular Basis Set for Cytokine-Induced Apoptosis , 2005, Science.
[47] R C Young,et al. Combination versus single agent chemotherapy: A review of the basis for selection of drug treatment of cancer , 1975, Cancer.
[48] N. Gulbahce,et al. Network medicine: a network-based approach to human disease , 2010, Nature Reviews Genetics.
[49] T. Pawson,et al. Network medicine , 2008, FEBS letters.
[50] Mindy I. Davis,et al. A quantitative analysis of kinase inhibitor selectivity , 2008, Nature Biotechnology.