Fluorescence Confocal Mosaicing Microscopy of Basal Cell Carcinomas to Potentially Guide Mohs Surgery

Fluorescence confocal mosaicing detects basal cell carcinomas in 10-20 mm-large Mohs surgical skin excisions within 5-9 minutes, compared to 20-45 minutes for frozen histology. Confocal mosaicing microscopy may enable rapid pathology-at-the-bedside to guide Mohs surgery.