Simulation of Focused, Scanned Ultrasonic Heating of Deep-Seated Tumors: The Effect of Blood Perfusion

Ahstmcr-The temperature distributions produced in deep-seated tumors by focused, scanned ultrasound are simulated. Power depositions are calculated using the Rayleigh-Sommerfeld diffraction integral and are then used as inputs to the two-dimensional bio-heat transfer equation to calculate tissue temperatures. The effects of normal tissue and tumor blood perfusions, tumor location and size, transducer scanning pattern, and transducer characteristics (frequency and f-number) are studied parametrically. The results are presented in terns of the range of applied powers that give acceptable heatings for each situation studied. Low frequency (0.5 MHz), small f-number (0.8) transducers are shown to produce acceptable heatings for a range of scanning patterns and blood perfusions.

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