Distribution and Kinetics of 3-O-Methyl-6-[18F]fluoro-L-DOPA in the Rhesus Monkey Brain

[1]  B. Agranoff,et al.  Use of [11C]Aminocyclohexanecarboxylate for the Measurement of Amino Acid Uptake and Distribution Volume in Human Brain , 1990, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[2]  A. Gjedde,et al.  Blood—Brain Transfer and Metabolism of 6-[18F]Fluoro-L-DOPA in Rat , 1990, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[3]  C. Patlak,et al.  Nigrostriatal function in humans studied with positron emission tomography , 1989, Annals of neurology.

[4]  R. Cohen,et al.  Quality control procedure for 6-[18F]fluoro-L-DOPA: a presynaptic PET imaging ligand for brain dopamine neurons. , 1989, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[5]  C. Nahmias,et al.  Metabolites of 6-[18F]fluoro-L-dopa in human blood. , 1988, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[6]  M. Häusser,et al.  Kinetics of in vitro decarboxylation and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat. , 1988, Biochemical pharmacology.

[7]  C Nahmias,et al.  Cerebral Metabolism of 6–[18F]Fluoro‐l‐3,4‐Dihydroxyphenylalanine in the Primate , 1987, Journal of neurochemistry.

[8]  E. Mcgeer,et al.  The Metabolism of [18F]6‐Fluoro‐l‐3,4‐Dihydroxyphenylalanine in the Hooded Rat , 1987, Journal of neurochemistry.

[9]  P. Cumming,et al.  Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects. , 1986, Life sciences.

[10]  D. Murphy,et al.  Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma, and their responses to inhibition of monoamine oxidase. , 1986, Clinical chemistry.

[11]  T Jones,et al.  Brain dopamine metabolism in patients with Parkinson's disease measured with positron emission tomography. , 1986, Journal of neurology, neurosurgery, and psychiatry.

[12]  Michael J. Adam,et al.  Positron emission tomography after MPTP: observations relating to the cause of Parkinson's disease , 1985, Nature.

[13]  A. Lang,et al.  Striatal dopamine distribution in Parkinsonian patients during life , 1985, Journal of the Neurological Sciences.

[14]  D. Jewett,et al.  A gas-solid-phase microchemical method for the synthesis of acetyl hypofluorite , 1984 .

[15]  C. Nahmias,et al.  Striatal dopamine metabolism in living monkeys examined by positron emission tomography , 1983, Brain Research.

[16]  M. Horne,et al.  A new autoradiographic approach for imaging forebrain dopamine distribution , 1982 .

[17]  R. Wurtman,et al.  The site of dopamine formation in rat striatum after L-dopa administration. , 1981, The Journal of pharmacology and experimental therapeutics.

[18]  C. Nahmias,et al.  Blood-brain barrier transport and cerebral utilization of dopa in living monkeys. , 1980, The American journal of physiology.

[19]  R. Katzman.,et al.  3-0-Methyldopa uptake and inhibition of L-dopa at the blood-brain barrier , 1975 .

[20]  L. Rivera-calimlim ABSORPTION, METABOLISM AND DISTRIBUTION OF [14C]‐O‐METHYLDOPA AND [14C]‐l‐DOPA AFTER ORAL ADMINISTRATION TO RATS , 1974, British Journal of Pharmacology.

[21]  D. Anderson,et al.  Species differences in the metabolism of orally administered dopamine-14C and N-alanyldopamine-14C. , 1973, Drug metabolism and disposition: the biological fate of chemicals.

[22]  T. Aigner,et al.  New rapid analysis method demonstrates differences in 6-[18F] fluoro-L-dopa plasma input curves with and without carbidopa and in hemi-MPTP lesioned monkeys. , 1991, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

[23]  C. Marsden,et al.  The effect of carbidopa on plasma and muscle levels of L‐dopa, dopamine, and their metabolites following L‐dopa administration to rats , 1988, Movement disorders : official journal of the Movement Disorder Society.

[24]  V. Yong,et al.  Asymptomatic striatal dopamine depletion: PET scans in unilateral MPTP monkeys , 1988, Synapse.

[25]  M. Horne,et al.  The cerebral metabolism of L-dihydroxyphenylalanine. An autoradiographic and biochemical study. , 1984, Pharmacology.

[26]  J. Genest,et al.  Conjugation patterns of endogenous plasma catecholamines in human and rat. A new specific method for analysis of glucuronide-conjugated catecholamines. , 1983, The Journal of laboratory and clinical medicine.