THE INFLUENCE OF IODINIZED OIL ON THE FUNCTION OF HYPOPHYSIS-THYROID SYSTEM AND THE CONTENS OF MIDDLE MOLECULE PEPTIDES IN HEALTHY PEOPLE DEPENDING ON IODINE SUPPLY OF THE BODY

The influence of iodinized oil (IO) on the function of hypophysis-thyroid system and the content of middle molecule peptides (MMP) in the blood serum in people of two groups living of biogeochemical zones with different levels of iodine deficiency expression has been investigated. Taking the iodinized oil during 14 days in the dose of 200 μg of iodine daily by the inhabitants of the Tissa-Danube lowland with less expressed iodine deficiency than in highlands, increases iodine dependence of the human body, decreases TSH content and the risk of goitre development, increases the excretion of iodine with urine and after a month’s taking it the mediane ioduria is achieved that corresponds to complete iodine sufficiency. Taking the IO by people constantly living in the Carpathians favours the increase of T 3 , T 4 hormone production, decreases TSH concentration to the norm in people living in better iodine ecological conditions, normalizes MMP production formation in tissues to the level of the inhabitants of lowlands and stimulates the increase of iodine with the urine.