The transition from controlled to compulsive drug use is associated with a loss of sensitization

[1]  N. Volkow,et al.  The neuroscience of addiction , 2005, Nature Neuroscience.

[2]  L. Parsons,et al.  Escalation of cocaine self‐administration does not depend on altered cocaine‐induced nucleus accumbens dopamine levels , 2003, Journal of neurochemistry.

[3]  T. Robinson,et al.  Locomotor sensitization to cocaine is associated with increased Fos expression in the accumbens, but not in the caudate , 2002, Behavioural Brain Research.

[4]  K. Vrana,et al.  Repeated Cocaine Self-Administration Causes Multiple Changes in Rat Frontal Cortex Gene Expression , 2002, Neurochemical Research.

[5]  G. Koob,et al.  Neurobiological evidence for hedonic allostasis associated with escalating cocaine use , 2002, Nature Neuroscience.

[6]  Barry J. Everitt,et al.  Psychomotor Stimulant Addiction: A Neural Systems Perspective , 2002, The Journal of Neuroscience.

[7]  H. Shaffer,et al.  Temporal progression of cocaine dependence symptoms in the US National Comorbidity Survey. , 2002, Addiction.

[8]  M. Krausz,et al.  Myths versus Evidence with Respect to Cocaine and Crack: Learning from the US Experience , 2001, European Addiction Research.

[9]  G. Koob,et al.  Drug Addiction, Dysregulation of Reward, and Allostasis , 2001, Neuropsychopharmacology.

[10]  K. Miczek,et al.  Reduction of zif268 messenger RNA expression during prolonged withdrawal following “binge” cocaine self-administration in rats , 2000, Neuroscience.

[11]  JaneR . Taylor,et al.  Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli , 1999, Psychopharmacology.

[12]  Mitsuo Nakamura,et al.  Neural systems for behavioral activation and reward , 1999, Current Opinion in Neurobiology.

[13]  G F Koob,et al.  Transition from moderate to excessive drug intake: change in hedonic set point. , 1998, Science.

[14]  G F Koob,et al.  Drug abuse: hedonic homeostatic dysregulation. , 1997, Science.

[15]  R. Christopher Pierce,et al.  A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants , 1997, Brain Research Reviews.

[16]  M. Kreek,et al.  Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during "binge"-pattern cocaine administration and chronic withdrawal. , 1996, The Journal of pharmacology and experimental therapeutics.

[17]  B. Cohen,et al.  Persistent reduction of immediate early gene mRNA in rat forebrain following single or multiple doses of cocaine. , 1994, Brain research. Molecular brain research.

[18]  S J Kish,et al.  Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self- administration , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[19]  K. Berridge,et al.  The neural basis of drug craving: An incentive-sensitization theory of addiction , 1993, Brain Research Reviews.

[20]  N. Goeders,et al.  Intracranial cocaine self-administration into the medial prefrontal cortex increases dopamine turnover in the nucleus accumbens. , 1993, The Journal of pharmacology and experimental therapeutics.

[21]  P Duffy,et al.  Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[22]  P. Kalivas,et al.  Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[23]  E. Ellinwood,et al.  Intermittent and Continuous cocaine Administration: Residual Behavioral states during withdrawal , 1992, Pharmacology Biochemistry and Behavior.

[24]  J S Fowler,et al.  Long‐Term frontal brain metabolic changes in cocaine abusers , 1992, Synapse.

[25]  S. Hyman,et al.  Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[26]  F. J. White,et al.  Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens. , 1991, The Journal of pharmacology and experimental therapeutics.

[27]  G F Koob,et al.  Postcocaine anhedonia: An animal model of cocaine withdrawal and its reversal by pharmacological treatments Athina Markou, M.A., Richard L. Hauger, M.D., George F. Koob, Ph.D. Department of Neuropharmacology, Research Institute of Scripps Clinic, La Jolla, CA 92037 , 1991, Biological Psychiatry.

[28]  F. Gawin.  Cocaine addiction: psychology and neurophysiology. , 1991, Science.

[29]  M. Iadarola,et al.  Cocaine induces striatal c-fos-immunoreactive proteins via dopaminergic D1 receptors. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[30]  A. Graybiel,et al.  Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[31]  M. Greenberg,et al.  The regulation and function of c-fos and other immediate early genes in the nervous system , 1990, Neuron.

[32]  L. Dwoskin,et al.  Persistence of neurochemical changes in dopamine systems after repeated cocaine administration. , 1990, The Journal of pharmacology and experimental therapeutics.

[33]  D J Henry,et al.  Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration. , 1989, The Journal of pharmacology and experimental therapeutics.

[34]  R. Tjian,et al.  Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. , 1989, Science.

[35]  M. Bardo,et al.  Prefrontal cortex lesions differentially disrupt cocaine-reinforced conditioned place preference but not conditioned taste aversion. , 1989, Behavioral neuroscience.

[36]  A. Crane,et al.  Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats. , 1988, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

[37]  Gawin Fh,et al.  Evolving conceptualizations of cocaine dependence. , 1988 .

[38]  A. Lajtha,et al.  Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice. , 1987, The Journal of pharmacology and experimental therapeutics.

[39]  G. Ellison,et al.  Continuous amphetamine intoxication: an animal model of the acute psychotic episode , 1983, Psychological Medicine.

[40]  N. Goeders,et al.  Cortical dopaminergic involvement in cocaine reinforcement. , 1983, Science.

[41]  P. Jatlow,et al.  Plasma cocaine concentrations during cocaine paste smoking. , 1982, Life sciences.

[42]  Fischman Mw,et al.  Cocaine self-administration in humans. , 1982 .

[43]  J. Kebabian,et al.  Multiple receptors for dopamine , 1979, Nature.

[44]  C. Johanson,et al.  Self-administration of psychomotor stimulant drugs: The effects of unlimited access , 1976, Pharmacology Biochemistry and Behavior.

[45]  Linda J. Porrino,et al.  Functional consequences of acute cocaine treatment depend on route of administration , 2005, Psychopharmacology.

[46]  C. Schuster,et al.  Psychomotor stimulant self administration as a function of dosage per injection in the Rhesus monkey , 2004, Psychopharmacologia.

[47]  F. Bloom,et al.  Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems , 2004, Psychopharmacology.

[48]  R. Pickens,et al.  Self-administration of d-amphetamine by rats , 2004, Psychopharmacologia.

[49]  M. Seevers,et al.  Self-administration of psychoactive substances by the monkey , 2004, Psychopharmacologia.

[50]  R. Hammer,et al.  Cocaine abstinence following chronic treatment alters cerebral metabolism in dopaminergic reward regions. Bromocriptine enhances recovery. , 1991, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

[51]  B. Moghaddam,et al.  Differential effect of cocaine on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens: Comparison to amphetamine , 1989, Synapse.

[52]  H. Kleber,et al.  Evolving conceptualizations of cocaine dependence. , 1988, The Yale journal of biology and medicine.

[53]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .

[54]  M W Fischman,et al.  Cocaine self-administration in humans. , 1982, Federation proceedings.

[55]  G. H. Williams,et al.  Drug addiction. , 1957, Pennsylvania medical journal.