Neurologic function in the optimally healthy oldest old

We examined cognition on a wide range of standardized neuropsychological tests in two groups of optimally healthy, elderly volunteers. One was composed of community-dwelling, functionally independent individuals aged 84 years and older, and the other group was nearly 20 years younger. The effect of aging was greatest on visual perceptual and constructional tasks rather than on memory tasks. Many cognitive functions were relatively well preserved in the optimally healthy oldest old.

[1]  C. P. Hughes,et al.  A New Clinical Scale for the Staging of Dementia , 1982, British Journal of Psychiatry.

[2]  E. Tangalos,et al.  Mayo's older americans normative studies: WAIS-R norms for ages 56 to 97 , 1992 .

[3]  William J. Hoyer,et al.  Attentional and perceptual processes in the study of cognitive aging. , 1980 .

[4]  I. T. Draper THE ASSESSMENT OF APHASIA AND RELATED DISORDERS , 1973 .

[5]  Harold Goodglass,et al.  Normative data on the boston diagnostic aphasia examination, parietal lobe battery, and the boston naming Test , 1980 .

[6]  A. Damasio,et al.  Normative observations on neuropsychological test performances in old age. , 1981, Journal of clinical neuropsychology.

[7]  J. Haxby,et al.  Patterns of performance preservation and loss in healthy aging , 1991 .

[8]  T. Farver,et al.  Performance of normal older adults on tests designed to measure parietal lobe functions. , 1982, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[9]  A. Benton,et al.  TEMPORAL ORIENTATION IN CEREBRAL DISEASE , 1964, The Journal of nervous and mental disease.

[10]  I. Rosenwaike A demographic portrait of the oldest old. , 1985, The Milbank Memorial Fund quarterly. Health and society.

[11]  James F. Malec,et al.  Mayo's older americans normative studies: WMS-R norms for ages 56 to 94 , 1992 .

[12]  G. Fillenbaum,et al.  The development, validity, and reliability of the OARS multidimensional functional assessment questionnaire. , 1981, Journal of gerontology.

[13]  W. V. van Gorp,et al.  Normative data on the Boston Naming Test for a group of normal older adults. , 1986, Journal of clinical and experimental neuropsychology.

[14]  L. Jarvik,et al.  Intellectual performance of octogenarians as a function of education and initial ability. , 1974, Human development.

[15]  D. Wechsler Manual for the Wechsler Adult Intelligence Scale. , 1955 .

[16]  S. Berg,et al.  Changes in cognitive functioning of the oldest old. , 1992, Journal of gerontology.

[17]  E. Kaplan,et al.  Neuropsychological test performance in Framingham: a descriptive study. , 1987, Psychological reports.

[18]  J Agnew,et al.  Age-related sex differences in verbal memory. , 1988, Journal of clinical psychology.

[19]  V. Leirer,et al.  Development and validation of a geriatric depression screening scale: a preliminary report. , 1982, Journal of psychiatric research.

[20]  Mark Byrd,et al.  Patterns of memory loss in three elderly samples. , 1987, Psychology and aging.

[21]  James S. Goodwin,et al.  A Normative Study of Russell's Variant of the Wechsler Memory Scale in a Healthy Elderly Population. , 1983 .

[22]  Robert A. Bornstein,et al.  The Wechsler Memory Scale—Revised , 1990 .

[23]  J Agnew,et al.  Age‐specific norms for the Mini‐Mental State Exam , 1988, Neurology.

[24]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[25]  D. Blazer,et al.  Self‐Rated Depression Scales and Screening for Major Depression in the Older Hospitalized Patient with Medical Illness , 1988, Journal of the American Geriatrics Society.

[26]  N Butters,et al.  Normal aging and forgetting rates on the Wechsler Memory Scale-Revised. , 1990, Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists.

[27]  J. Morris,et al.  The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assesment of Alzheimer's disease , 1989, Neurology.

[28]  Denise C. Park,et al.  Handbook of the Psychology of Aging , 1979 .

[29]  N Butters,et al.  Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures. , 1991, Archives of neurology.