Clinical use of controlled oxygenated rewarming of kidney grafts prior to transplantation by ex vivo machine perfusion. A pilot study

Sudden restoration of normothermic conditions upon reperfusion of cold‐stored grafts has been suggested to entail a massive energy demand not yet met by the cells that still suffer from hypothermic torpor. An adapted and gentle rise of graft temperature by ex‐vivo machine perfusion has, therefore, been proposed. This should now be tested in the clinical setting.

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