Muscle strength and functional performance in patients with anterior cruciate ligament injury treated with training and surgical reconstruction or training only: a two to five-year followup.

OBJECTIVE To study muscle strength and functional performance in patients with anterior cruciate ligament (ACL) injury with or without surgical reconstruction 2 to 5 years after injury. Good muscle function is important in preventing early-onset osteoarthritis (OA), but the role of reconstructive surgery in restoring muscle function is unclear. METHODS Of 121 patients with ACL injury included in a randomized controlled trial on training and surgical reconstruction versus training only (the Knee, Anterior cruciate ligament, NON-surgical versus surgical treatment [KANON] study, ISRCTN: 84752559), 54 (mean age at followup 30 years, range 20-39, 28% women) were assessed a mean +/- SD of 3 +/- 0.9 years after injury with reliable, valid, and responsive test batteries for strength (knee extension, knee flexion, leg press) and hop performance (vertical jump, one-leg hop, side hop). The Limb Symmetry Index (LSI; injured leg divided by uninjured and multiplied by 100) value and absolute values were used for comparisons between groups (analysis of variance). An LSI >or=90% was considered normal. RESULTS There were no differences between the surgical and nonsurgical treatment groups in muscle strength or functional performance. Between 44% and 89% of subjects had normal muscle function in the single tests, and between 44% and 56% had normal function in the test batteries. CONCLUSION The lack of differences between patients treated with training and surgical reconstruction or training only indicates that reconstructive surgery is not a prerequisite for restoring muscle function. Abnormal muscle function, found in approximately one-third or more of the patients, may be a predictor of future knee OA.

[1]  M. Kalady,et al.  Thigh muscle size and strength after anterior cruciate ligament reconstruction and rehabilitation. , 1997, The Journal of orthopaedic and sports physical therapy.

[2]  W. Frontera,et al.  Muscle fatigue and muscle injury. , 2000, Physical medicine and rehabilitation clinics of North America.

[3]  L R Osternig,et al.  2 Isokinetic Dynamometry: Implications for Muscle Testing and Rehabilitation , 1986 .

[4]  M Lysholm,et al.  A performance test to monitor rehabilitation and evaluate anterior cruciate ligament injuries , 1986, The American journal of sports medicine.

[5]  T. Carter,et al.  Isokinetic evaluation of anterior cruciate ligament reconstruction: hamstring versus patellar tendon. , 1999, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[6]  F R Noyes,et al.  Abnormal lower limb symmetry determined by function hop tests after anterior cruciate ligament rupture , 1991, The American journal of sports medicine.

[7]  C. Ekdahl,et al.  Knee injury and Osteoarthritis Outcome Score (KOOS) ‐ validation of a Swedish version , 1998, Scandinavian journal of medicine & science in sports.

[8]  B. Beynnon,et al.  Risk factors for lower extremity injury: a review of the literature , 2003, British journal of sports medicine.

[9]  R. Thomeé,et al.  Ability of closed and open kinetic chain tests of muscular strength to assess functional performance , 2000, Scandinavian journal of medicine & science in sports.

[10]  G. Dahlberg,et al.  Statistical Methods for Medical and Biological Students , 1941, The Indian Medical Gazette.

[11]  J. Karlsson,et al.  Single‐leg hop testing following fatiguing exercise: reliability and biomechanical analysis , 2006, Scandinavian journal of medicine & science in sports.

[12]  E. Roos,et al.  The challenge of recruiting patients with anterior cruciate ligament injury of the knee into a randomized clinical trial comparing surgical and non-surgical treatment. , 2007, Contemporary clinical trials.

[13]  R U Newton,et al.  The optimal training load for the development of dynamic athletic performance. , 1993, Medicine and science in sports and exercise.

[14]  J. Petrella,et al.  Age differences in knee extension power, contractile velocity, and fatigability. , 2005, Journal of applied physiology.

[15]  M. Axe,et al.  The effect of insufficient quadriceps strength on gait after anterior cruciate ligament reconstruction. , 2002, Clinical biomechanics.

[16]  M. Kurosaka,et al.  Evaluation of functional deficits determined by four different hop tests in patients with anterior cruciate ligament deficiency , 1998, Knee Surgery, Sports Traumatology, Arthroscopy.

[17]  E. Roos,et al.  Clinical update: treating osteoarthritis , 2007, The Lancet.

[18]  E. Phillips,et al.  A dynamic test of lower extremity function following anterior cruciate ligament reconstruction and rehabilitation. , 1997, The Journal of orthopaedic and sports physical therapy.

[19]  G. Grimby Physical activity and muscle training in the elderly. , 2009, Acta medica Scandinavica. Supplementum.

[20]  D. Beard,et al.  Changes in muscle torque following anterior cruciate ligament reconstruction: A comparison between hamstrings and patella tendon graft procedures on 45 patients , 2002, Acta orthopaedica Scandinavica.

[21]  J. Taunton,et al.  The effects of proprioceptive or strength training on the neuromuscular function of the ACL reconstructed knee: a randomized clinical trial , 2003, Scandinavian journal of medicine & science in sports.

[22]  F. Awiszus,et al.  Effects of reconstruction of the anterior cruciate ligament on voluntary activation of quadriceps femoris a prospective twitch interpolation study. , 2001, The Journal of bone and joint surgery. British volume.

[23]  R Petschnig,et al.  The relationship between isokinetic quadriceps strength test and hop tests for distance and one-legged vertical jump test following anterior cruciate ligament reconstruction. , 1998, The Journal of orthopaedic and sports physical therapy.

[24]  J. Karlsson,et al.  Effect of Pre‐Exhaustion Exercise on Lower‐Extremity Muscle Activation During a Leg Press Exercise , 2003, Journal of strength and conditioning research.

[25]  J. Bullock-Saxton,et al.  Muscle strength and function before and after anterior cruciate ligament reconstruction using semitendonosus and gracilis. , 2001, The Knee.

[26]  D. Beard,et al.  Hamstrings vs. patella tendon for anterior cruciate ligament reconstruction: a randomised controlled trial. , 2001, The Knee.

[27]  K. Shelbourne,et al.  Accelerated rehabilitation after anterior cruciate ligament reconstruction , 1990, The American journal of sports medicine.

[28]  M. Waldén,et al.  Review of knee proprioception and the relation to extremity function after an anterior cruciate ligament rupture. , 2001, The Journal of orthopaedic and sports physical therapy.

[29]  S. W. Stevenson,et al.  Use of Electrical Stimulation in Strength and Power Training , 2008 .

[30]  L. Huston,et al.  Longitudinal Effects of Anterior Cruciate Ligament Injury and Patellar Tendon Autograft Reconstruction on Neuromuscular Performance , 2000, The American journal of sports medicine.

[31]  M. Axe,et al.  Laxity, instability, and functional outcome after ACL injury: copers versus noncopers. , 1999, Medicine and science in sports and exercise.

[32]  L. Engebretsen,et al.  Clinical, Functional, and Radiologic Outcome in Team Handball Players 6 to 11 Years after Anterior Cruciate Ligament Injury , 2003, The American journal of sports medicine.

[33]  E. Roos,et al.  Joint injury causes knee osteoarthritis in young adults , 2005, Current opinion in rheumatology.

[34]  D. Fithian,et al.  Fate of the anterior cruciate ligament-injured knee. , 2002, The Orthopedic clinics of North America.

[35]  J. Feagin,et al.  Consideration of the anterior cruciate ligament injury in skiing. , 1987, Clinical orthopaedics and related research.

[36]  K. Shelbourne,et al.  The O'Donoghue triad revisited , 1991, The American journal of sports medicine.

[37]  E. Roos,et al.  High prevalence of osteoarthritis 14 years after an anterior cruciate ligament tear in male soccer players: a study of radiographic and patient relevant outcomes , 2004, Annals of the rheumatic diseases.

[38]  R. Patterson,et al.  Strength testing with a portable dynamometer: reliability for upper and lower extremities. , 1987, Archives of physical medicine and rehabilitation.

[39]  J. Karlsson,et al.  Analysis of subjective, objective and functional examination tests after anterior cruciate ligament reconstruction A follow-up of 527 patients , 1999, Knee Surgery, Sports Traumatology, Arthroscopy.

[40]  G. Salem,et al.  Bilateral kinematic and kinetic analysis of the squat exercise after anterior cruciate ligament reconstruction. , 2003, Archives of physical medicine and rehabilitation.

[41]  M. Axe,et al.  A decision-making scheme for returning patients to high-level activity with nonoperative treatment after anterior cruciate ligament rupture , 2000, Knee Surgery, Sports Traumatology, Arthroscopy.

[42]  A. K. Aune,et al.  Subjective functional assessments and the return to competitive sport after anterior cruciate ligament reconstruction , 2004, British Journal of Sports Medicine.

[43]  A. Ekeland,et al.  Prospective study of changes in impairments and disabilities after anterior cruciate ligament reconstruction. , 1999, The Journal of orthopaedic and sports physical therapy.

[44]  Ian Shrier,et al.  Muscle dysfunction versus wear and tear as a cause of exercise related osteoarthritis: an epidemiological update , 2004, British Journal of Sports Medicine.

[45]  M Solomonow,et al.  Sensorimotor control of knee stability. A review , 2001, Scandinavian journal of medicine & science in sports.

[46]  Bruce M Gansneder,et al.  Strength, Functional Outcome, and Postural Stability After Anterior Cruciate Ligament Reconstruction. , 2002, Journal of athletic training.

[47]  Michael D. Lewek,et al.  A systematic review of evidence for anterior cruciate ligament rehabilitation: how much and what type? , 2004 .

[48]  K. Shelbourne,et al.  Rehabilitation program for both knees when the contralateral autogenous patellar tendon graft is used for primary anterior cruciate ligament reconstruction: a case study. , 1999, The Journal of orthopaedic and sports physical therapy.

[49]  B. Beynnon,et al.  Knee Injury and Osteoarthritis Outcome Score (KOOS)--development of a self-administered outcome measure. , 1998, The Journal of orthopaedic and sports physical therapy.

[50]  A. Malmivaara,et al.  Surgical versus conservative interventions for anterior cruciate ligament ruptures in adults. , 2016, The Cochrane database of systematic reviews.

[51]  K. Pfeifer,et al.  Motor performance in different dynamic tests in knee rehabilitation , 1999, Scandinavian journal of medicine & science in sports.

[52]  M. Hurley Muscle dysfunction and effective rehabilitation of knee osteoarthritis: what we know and what we need to find out. , 2003, Arthritis and rheumatism.

[53]  H. Roos,et al.  Isokinetic knee extensor strength and functional performance in healthy female soccer players , 1998, Scandinavian journal of medicine & science in sports.

[54]  T. Rudroff Functional capability is enhanced with semitendinosus than patellar tendon ACL repair. , 2003, Medicine and science in sports and exercise.

[55]  Joanna Kvist,et al.  Rehabilitation Following Anterior Cruciate Ligament Injury , 2004, Sports medicine.

[56]  K. Kaufman,et al.  Fate of the ACL-injured Patient , 1994, The American journal of sports medicine.

[57]  E. Ageberg,et al.  15-Year Follow-up of Neuromuscular Function in Patients with Unilateral Nonreconstructed Anterior Cruciate Ligament Injury Initially Treated with Rehabilitation and Activity Modification , 2007, The American journal of sports medicine.

[58]  L. Jacobsson,et al.  Reduced functional performance in the lower extremity predicted radiographic knee osteoarthritis five years later , 2004, Annals of the rheumatic diseases.

[59]  L. B. Augestad,et al.  Isokinetic muscle strength after anterior cruciate ligament reconstruction , 1998, Scandinavian journal of medicine & science in sports.

[60]  Eva Ageberg,et al.  Consequences of a ligament injury on neuromuscular function and relevance to rehabilitation - using the anterior cruciate ligament-injured knee as model. , 2002, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[61]  Leo A. Pinczewski,et al.  A 10-Year Comparison of Anterior Cruciate Ligament Reconstructions with Hamstring Tendon and Patellar Tendon Autograft , 2007 .

[62]  R. Thomeé,et al.  Weight training of the thigh muscles using closed vs. open kinetic chain exercises: a comparison of performance enhancement. , 1998, The Journal of orthopaedic and sports physical therapy.

[63]  L. Herrington,et al.  A systematic literature review to investigate if we identify those patients who can cope with anterior cruciate ligament deficiency. , 2006, The Knee.

[64]  F. Harrell,et al.  Anterior Cruciate Ligament Reconstruction Autograft Choice: Bone-Tendon-Bone versus Hamstring , 2004, The American journal of sports medicine.

[65]  Barbara S Smith,et al.  Test–Retest Reliability of Lower Extremity Functional Tests After a Closed Kinetic Chain Isokinetic Testing Bout , 2003 .

[66]  M. Paterno,et al.  The test-retest reliability of a one legged hop for distance in young adults with and without ACL reconstruction , 1996 .

[67]  A. Ekeland,et al.  Assessment of functional tests after anterior cruciate ligament surgery. , 1994, The Journal of orthopaedic and sports physical therapy.

[68]  J. Lysholm,et al.  Rating systems in the evaluation of knee ligament injuries. , 1985, Clinical orthopaedics and related research.

[69]  Michael D Ross,et al.  The relationship between participation restrictions and selected clinical measures following anterior cruciate ligament reconstruction , 2001, Knee Surgery, Sports Traumatology, Arthroscopy.

[70]  Braden C Fleming,et al.  Rehabilitation after Anterior Cruciate Ligament Reconstruction: A Prospective, Randomized, Double-Blind Comparison of Programs Administered over 2 Different Time Intervals , 2005, The American journal of sports medicine.

[71]  E M Braunstein,et al.  Reduced quadriceps strength relative to body weight: a risk factor for knee osteoarthritis in women? , 1998, Arthritis and rheumatism.

[72]  J. Bullock-Saxton,et al.  The relationship between knee strength and functional stability before and after anterior cruciate ligament reconstruction , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[73]  L. Hiemstra,et al.  Knee strength deficits after hamstring tendon and patellar tendon anterior cruciate ligament reconstruction. , 2000, Medicine and science in sports and exercise.

[74]  S M Lephart,et al.  Effects of rest interval on isokinetic strength and functional performance after short-term high intensity training. , 1997, British journal of sports medicine.

[75]  Douglas G. Altman,et al.  Practical statistics for medical research , 1990 .

[76]  K. Refshauge,et al.  Long-term Outcome of Endoscopic Anterior Cruciate Ligament Reconstruction with Patellar Tendon Autograft , 2006, The American journal of sports medicine.

[77]  Jesper Augustsson,et al.  A test battery for evaluating hop performance in patients with an ACL injury and patients who have undergone ACL reconstruction , 2006, Knee Surgery, Sports Traumatology, Arthroscopy.

[78]  Freddie H. Fu,et al.  Factors contributing to function of the knee joint after injury or reconstruction of the anterior cruciate ligament. , 1999, Instructional course lectures.

[79]  J. Fleiss,et al.  Intraclass correlations: uses in assessing rater reliability. , 1979, Psychological bulletin.

[80]  Freddie H. Fu,et al.  A pilot study on the relationship between physical impairment and activity restriction in persons with anterior cruciate ligament reconstruction at long-term follow-up , 2001, Knee Surgery, Sports Traumatology, Arthroscopy.

[81]  F R Noyes,et al.  Quantitative assessment of functional limitations in normal and anterior cruciate ligament-deficient knees. , 1990, Clinical orthopaedics and related research.

[82]  Jesper Augustsson,et al.  Ability of a new hop test to determine functional deficits after anterior cruciate ligament reconstruction , 2004, Knee Surgery, Sports Traumatology, Arthroscopy.

[83]  P. Kannus,et al.  Is it Possible to Prevent Sports Injuries? , 2002, Sports medicine.

[84]  S. Blair,et al.  Lower Extremity Muscle Strength and Risk of Self-Reported Hip or Knee Osteoarthritis , 2004 .

[85]  K. Shelbourne,et al.  Accelerated Rehabilitation after Anterior Cruciate Ligament Reconstruction1 , 1992 .

[86]  K E Wilk,et al.  The relationship between subjective knee scores, isokinetic testing, and functional testing in the ACL-reconstructed knee. , 1994, The Journal of orthopaedic and sports physical therapy.

[87]  S. Hurwitz,et al.  Lower extremity compensations following anterior cruciate ligament reconstruction. , 2000, Physical therapy.

[88]  G. Sleivert,et al.  The influence of a strength-sprint training sequence on multi-joint power output. , 1995, Medicine and science in sports and exercise.

[89]  K. Webster,et al.  Early post-operative morbidity following anterior cruciate ligament reconstruction: patellar tendon versus hamstring graft , 2001, Knee Surgery, Sports Traumatology, Arthroscopy.

[90]  D. Hedden,et al.  Effects of an Accelerated Rehabilitation Program after Anterior Cruciate Ligament Reconstruction with Combined Semitendinosus-Gracilis Autograft and a Ligament Augmentation Device , 1995, The American journal of sports medicine.

[91]  J. Karlsson,et al.  Functional outcome of anterior cruciate ligament reconstruction in recreational and competitive athletes , 2001, Scandinavian journal of medicine & science in sports.

[92]  M. Paterno,et al.  Relationship of knee extensor strength and hopping test performance in the assessment of lower extremity function. , 1995, The Journal of orthopaedic and sports physical therapy.

[93]  H. Roos,et al.  Injury risk factors in female European football. A prospective study of 123 players during one season , 2000, Scandinavian journal of medicine & science in sports.

[94]  Braden C Fleming,et al.  The science of anterior cruciate ligament rehabilitation. , 2002, Clinical orthopaedics and related research.

[95]  C. Taylor,et al.  Brace-Free Rehabilitation, with Early Return to Activity, for Knees Reconstructed with a Double-Looped Semitendinosus and Gracilis Graft*† , 1996, The Journal of bone and joint surgery. American volume.

[96]  Robert U Newton,et al.  American College of Sports Medicine position stand. Progression models in resistance training for healthy adults. , 2011, Medicine and science in sports and exercise.

[97]  A A Sapega,et al.  Muscle performance evaluation in orthopaedic practice. , 1990, The Journal of bone and joint surgery. American volume.

[98]  J. Karlsson,et al.  Anterior cruciate ligament instability and reconstruction Review of current trends in treatment , 1998, Scandinavian journal of medicine & science in sports.

[99]  Jesper Augustsson,et al.  Development of a strength test battery for evaluating leg muscle power after anterior cruciate ligament injury and reconstruction , 2006, Knee Surgery, Sports Traumatology, Arthroscopy.

[100]  S. Lephart,et al.  Relation Between Open and Closed Kinematic Chain Assessment of Knee Strength and Functional Performance , 1997, Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine.

[101]  A. Ekeland,et al.  Reliability of functional knee tests in normal athletes , 1995, Scandinavian journal of medicine & science in sports.

[102]  E. Roos,et al.  The Long-term Consequence of Anterior Cruciate Ligament and Meniscus Injuries , 2007, The American journal of sports medicine.