Anterior segment imaging: ultrasound biomicroscopy and anterior segment optical coherence tomography

Purpose of review Recent advances in ocular imaging have included high-resolution techniques for visualizing the anterior segment and angle structures. This review will describe the two main anterior segment imaging modalities and summarize their applications, strengths and weaknesses. Recent findings Ultrasound biomicroscopy and more recently anterior segment optical coherence tomography are imaging modalities that can be used to obtain two-dimensional images of the angle and surrounding structures. Ultrasound biomicroscopy has the advantage of being able to illustrate the ciliary body and therefore give clinicians information on nonpupil block mechanisms of primary angle closure and also diagnose other abnormalities such as cyclodialysis clefts. Anterior segment optical coherence tomography is a noncontact and rapid method of imaging the angle and anterior segment that has great potential in the diagnosis and follow-up of patients with angle closure. This article will discuss these and other applications and compare and contrast the two technologies. Summary Rapid advances in anterior segment imaging are enlightening clinicians and researchers to the importance in making the diagnosis of primary angle closure, trying to establish underlying causal mechanisms, and evaluating treatments. Although they do not replace conventional angle and anterior segment examination, they hold great potential for the future.

[1]  C. Cheung,et al.  Repeatability and reproducibility of anterior chamber angle measurement with anterior segment optical coherence tomography , 2007, British Journal of Ophthalmology.

[2]  R. Ritch,et al.  Plateau iris syndrome in younger patients , 2007, Clinical & experimental ophthalmology.

[3]  L. Bachmann,et al.  Prevalence of plateau iris syndrome in young patients with recurrent angle closure , 2007, Clinical & experimental ophthalmology.

[4]  K. Barton,et al.  Visualization of aqueous shunt position and patency using anterior segment optical coherence tomography. , 2007, American journal of ophthalmology.

[5]  J Moreno-Montañés,et al.  Optical coherence tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism. , 2000, Ophthalmology.

[6]  Robert Ritch,et al.  Agreement between gonioscopy and ultrasound biomicroscopy in detecting iridotrabecular apposition. , 2007, Archives of ophthalmology.

[7]  D. Friedman,et al.  Changes in anterior segment morphology in response to illumination and after laser iridotomy in Asian eyes: an anterior segment OCT study , 2007, British Journal of Ophthalmology.

[8]  Tin Aung,et al.  Reproducibility of anterior chamber angle measurements obtained with anterior segment optical coherence tomography. , 2007, Investigative ophthalmology & visual science.

[9]  David Huang,et al.  Optical coherence tomography imaging of the anterior chamber angle. , 2005, Ophthalmology clinics of North America.

[10]  G. Dahmen,et al.  Anterior chamber angle measurement with optical coherence tomography: Intraobserver and interobserver variability , 2006, Journal of cataract and refractive surgery.

[11]  Tin Aung,et al.  Imaging of trabeculectomy blebs using anterior segment optical coherence tomography. , 2007, Ophthalmology.

[12]  R Ritch,et al.  Quantitative assessment of the anterior segment using ultrasound biomicroscopy. , 2000, Current opinion in ophthalmology.

[13]  J. Izatt,et al.  Real-time optical coherence tomography of the anterior segment at 1310 nm. , 2001, Archives of ophthalmology.

[14]  Tanuj Dada,et al.  Comparison of anterior segment optical coherence tomography and ultrasound biomicroscopy for assessment of the anterior segment , 2007, Journal of cataract and refractive surgery.

[15]  D. Friedman,et al.  Detection of primary angle closure using anterior segment optical coherence tomography in Asian eyes. , 2007, Ophthalmology.

[16]  R. Bansal,et al.  Ultrasound biomicroscopic quantification of the change in anterior chamber angle following laser peripheral iridotomy in early chronic primary angle closure glaucoma , 2007, Eye.

[17]  Tin Aung,et al.  Anterior segment optical coherence tomography imaging of trabeculectomy blebs before and after laser suture lysis. , 2007, American journal of ophthalmology.

[18]  Mingguang He,et al.  Laser peripheral iridotomy in eyes with narrow drainage angles: ultrasound biomicroscopy outcomes. The Liwan Eye Study. , 2007, Ophthalmology.

[19]  R Ritch,et al.  Ultrasound biomicroscopy dark room provocative testing: a quantitative method for estimating anterior chamber angle width. , 1999, Japanese journal of ophthalmology.

[20]  Tin Aung,et al.  Prevalence of plateau iris in primary angle closure suspects an ultrasound biomicroscopy study. , 2008, Ophthalmology.

[21]  F. Foster,et al.  Ultrasound biomicroscopy of anterior segment structures in normal and glaucomatous eyes. , 1992, American journal of ophthalmology.

[22]  Joseph A Izatt,et al.  Comparison of optical coherence tomography and ultrasound biomicroscopy for detection of narrow anterior chamber angles. , 2005, Archives of ophthalmology.

[23]  K. Gündüz,et al.  The Use of Ultrasound Biomicroscopy in the Evaluation of Anterior Segment Tumors and Simulating Conditions , 2007, Ophthalmologica.

[24]  R. Birngruber,et al.  Filtering Bleb Evaluation with Slit-Lamp–Adapted 1310-nm Optical Coherence Tomography , 2006, Current eye research.

[25]  A. Day,et al.  Optical coherence tomography in anterior segment imaging. , 2007, Acta ophthalmologica Scandinavica.

[26]  Christopher Kai-shun Leung,et al.  Analysis of bleb morphology after trabeculectomy with Visante anterior segment optical coherence tomography , 2006, British Journal of Ophthalmology.

[27]  Robert Ritch,et al.  Narrow angles and angle closure: anatomic reasons for earlier closure of the superior portion of the iridocorneal angle. , 2007, Archives of ophthalmology.

[28]  Yan Li,et al.  Anterior segment optical coherence tomography for imaging the anterior chamber after laser peripheral iridotomy. , 2007, American journal of ophthalmology.

[29]  J. Dawczynski,et al.  Anterior Segment Optical Coherence Tomography for Evaluation of Changes in Anterior Chamber Angle and Depth after Intraocular Lens Implantation in Eyes with Glaucoma , 2007, European journal of ophthalmology.