Optimisation of an automated drusen-quantifying software for the analysis of drusen distribution in patients with age-related macular degeneration

[1]  N. Otsu A threshold selection method from gray level histograms , 1979 .

[2]  Michalis E. Zervakis,et al.  Detection and segmentation of drusen deposits on human retina: Potential in the diagnosis of age-related macular degeneration , 2003, Medical Image Anal..

[3]  Monique M. B. Breteler,et al.  The Rotterdam Study: 2016 objectives and design update , 2015, European Journal of Epidemiology.

[4]  G. Quellec,et al.  Computational quantification of complex fundus phenotypes in age-related macular degeneration and Stargardt disease. , 2011, Investigative ophthalmology & visual science.

[5]  S. Sivaprasad,et al.  Retinal Sensitivity Is Reduced With The Increase Of Drusen Load In Fellow Eye Of Patients With Neovascular Age-related Macular Degeneration , 2012 .

[6]  Christian Ahlers,et al.  Performance of drusen detection by spectral-domain optical coherence tomography. , 2010, Investigative ophthalmology & visual science.

[7]  David S. Shin,et al.  Computer-assisted, interactive fundus image processing for macular drusen quantitation. , 1999, Ophthalmology.

[8]  Jennifer I. Lim,et al.  A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. , 2001, Archives of ophthalmology.

[9]  A. Hofman,et al.  Determinants of disease and disability in the elderly: The Rotterdam elderly study , 1991, European Journal of Epidemiology.

[10]  R. T. Smith,et al.  Automated detection of macular drusen using geometric background leveling and threshold selection. , 2005, Archives of ophthalmology.

[11]  A Hofman,et al.  Incidence and progression rates of age-related maculopathy: the Rotterdam Study. , 2001, Investigative ophthalmology & visual science.

[12]  Pell,et al.  Drusen Measurement from Fundus Photographs Using Computer Image Analysis , 2008 .