Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH

[1]  Qingrong Chen,et al.  Optimal transfection with the HK polymer depends on its degree of branching and the pH of endocytic vesicles. , 2002, Nucleic acids research.

[2]  N. M. Rao,et al.  Anchor dependency for non-glycerol based cationic lipofectins: mixed bag of regular and anomalous transfection profiles. , 2002, Chemistry.

[3]  A. Chaudhuri,et al.  Anchor-dependent lipofection with non-glycerol based cytofectins containing single 2-hydroxyethyl head groups. , 2002, Biochimica et biophysica acta.

[4]  C. Springer,et al.  Synthesis of novel cationic lipids: effect of structural modification on the efficiency of gene transfer. , 2002, Journal of medicinal chemistry.

[5]  N. M. Rao,et al.  Novel non-glycerol-based cytofectins with lactic acid-derived head groups. , 2001, Biochemical and biophysical research communications.

[6]  C. Pichon,et al.  Histidine-rich peptides and polymers for nucleic acids delivery. , 2001, Advanced drug delivery reviews.

[7]  N. M. Rao,et al.  Design, synthesis, and transfection biology of novel cationic glycolipids for use in liposomal gene delivery. , 2001, Journal of medicinal chemistry.

[8]  D. Scherman,et al.  Sterically stabilized BGTC‐based lipoplexes: structural features and gene transfection into the mouse airways in vivo , 2001, The journal of gene medicine.

[9]  C. Férec,et al.  Cation substitution in cationic phosphonolipids: a new concept to improve transfection activity and decrease cellular toxicity. , 2000, Journal of medicinal chemistry.

[10]  S. Stass,et al.  Co-polymer of histidine and lysine markedly enhances transfection efficiency of liposomes , 2000, Gene Therapy.

[11]  S. W. Kim,et al.  pH-sensitive cationic polymer gene delivery vehicle: N-Ac-poly(L-histidine)-graft-poly(L-lysine) comb shaped polymer. , 2000, Bioconjugate chemistry.

[12]  C. Férec,et al.  Systemic administration of cationic phosphonolipids/DNA complexes and the relationship between formulation and lung transfection efficiency. , 2000, Biochimica et biophysica acta.

[13]  A. Mountain,et al.  Gene therapy: the first decade. , 2000, Trends in biotechnology.

[14]  Guénin,et al.  Cationic Phosphonolipids Containing Quaternary Phosphonium and Arsonium Groups for DNA Transfection with Good Efficiency and Low Cellular Toxicity** , 2000, Angewandte Chemie.

[15]  W. Tseng,et al.  Subcellular trafficking of the cytoplasmic expression system. , 1999, Human gene therapy.

[16]  N. M. Rao,et al.  Novel series of non-glycerol-based cationic transfection lipids for use in liposomal gene delivery. , 1999, Journal of medicinal chemistry.

[17]  Wong,et al.  Biological barriers to cellular delivery of lipid-based DNA carriers. , 1999, Advanced drug delivery reviews.

[18]  M. Monsigny,et al.  Efficient gene transfer by histidylated polylysine/pDNA complexes. , 1999, Bioconjugate chemistry.

[19]  J. Hughes,et al.  Introduction of a disulfide bond into a cationic lipid enhances transgene expression of plasmid DNA. , 1998, Biochemical and biophysical research communications.

[20]  I. Verma,et al.  Gene therapy - promises, problems and prospects , 1997, Nature.

[21]  L. Huang,et al.  Delivery of a PCR amplified DNA fragment into cells: a model for using synthetic genes for gene therapy , 1997, Gene Therapy.

[22]  M. Ichelpeuchmaur.  Gene transfer by guanidinium-cholesterol cationic lipids into airway epithelial cells in vitro and in vivo , 1997 .

[23]  F. Szoka,et al.  Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. , 1996, Biochemistry.

[24]  D. Friend,et al.  Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes. , 1996, Biochimica et biophysica acta.

[25]  Xiang Gao,et al.  Cationic liposome-mediated gene transfer. , 1995, Gene therapy.

[26]  Joseph Zabner,et al.  Cellular and Molecular Barriers to Gene Transfer by a Cationic Lipid (*) , 1995, The Journal of Biological Chemistry.

[27]  H. Deng,et al.  Self-amplifying expression from the T7 promoter in 3T3 mouse fibroblasts. , 1994, Gene.

[28]  L. Huang,et al.  A sustained, cytoplasmic transgene expression system delivered by cationic liposomes. , 1994, Biochemical and biophysical research communications.

[29]  L. Huang,et al.  Cytoplasmic expression of a reporter gene by co-delivery of T7 RNA polymerase and T7 promoter sequence with cationic liposomes. , 1993, Nucleic acids research.

[30]  H. Hill,et al.  Protein determination using bicinchoninic acid in the presence of sulfhydryl reagents. , 1988, Analytical biochemistry.

[31]  J. Northrop,et al.  Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[32]  K. Wood,et al.  Firefly luciferase gene: structure and expression in mammalian cells , 1987, Molecular and cellular biology.

[33]  P. K. Smith,et al.  Measurement of protein using bicinchoninic acid. , 1985, Analytical biochemistry.

[34]  D. Hoekstra,et al.  Use of resonance energy transfer to monitor membrane fusion. , 1981, Biochemistry.

[35]  T. Chen,et al.  In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain. , 1977, Experimental cell research.