Experimental comparative mixing performance of passive micromixers with H-shaped sub-channels

Abstract This paper presents a new type of passive microfluidic mixer called the “H-micromixer”. This type of passive micromixer is based on the splitting and recombination (SAR) process, meaning that the two fluids to be mixed are split and recombined to optimize the diffusion process. The paper also describes an experimental investigation of the mixing process in three different geometries: T-micromixer, O-micromixer and H-micromixer. The laminar flow regime (0.08 Re Re =0.083.

[1]  Seung S. Lee,et al.  Rotation effect in split and recombination micromixing , 2008 .

[2]  M. Paraschivoiu,et al.  Single-phase fluid flow and mixing in microchannels , 2011 .

[3]  Chih-Ming Ho,et al.  An unsteady microfluidic T-form mixer perturbed by hydrodynamic pressure , 2008, Journal of micromechanics and microengineering : structures, devices, and systems.

[4]  Akira Goto,et al.  On multi-objective optimization of geometry of staggered herringbone micromixer , 2009 .

[5]  Dong Sung Kim,et al.  Improved serpentine laminating micromixer with enhanced local advection , 2008 .

[6]  Chee Burm Shin,et al.  Design and simulation of passive mixing in microfluidic systems with geometric variations , 2009 .

[7]  C. Shu,et al.  Chaotic micromixers using two-layer crossing channels to exhibit fast mixing at low Reynolds numbers. , 2005, Lab on a chip.

[8]  Che-Hsin Lin,et al.  A rapid DNA digestion system , 2007, Biomedical microdevices.

[9]  T. G. Kang,et al.  A chaotic serpentine mixer efficient in the creeping flow regime: from design concept to optimization , 2009 .

[10]  Kazuhiro Mae,et al.  Design method for micromixers considering influence of channel confluence and bend on diffusion length , 2011 .

[11]  T. R. Shih,et al.  A high-efficiency planar micromixer with convection and diffusion mixing over a wide Reynolds number range , 2008 .

[12]  Samuel K Sia,et al.  Mixing with bubbles: a practical technology for use with portable microfluidic devices. , 2006, Lab on a chip.

[13]  Hengzi Wang,et al.  Numerical investigation of mixing in microchannels with patterned grooves , 2003 .

[14]  Kwang-Yong Kim,et al.  Analysis and optimization of a micromixer with a modified Tesla structure , 2010 .

[15]  Bumkyoo Choi,et al.  A study on the novel micromixer with chaotic flows , 2008 .

[16]  V Hessel,et al.  An optimised split-and-recombine micro-mixer with uniform chaotic mixing. , 2004, Lab on a chip.

[17]  D. Bothe,et al.  Fully resolved numerical simulation of reactive mixing in a T-shaped micromixer using parabolized species equations☆ , 2011 .

[18]  Ping-Chiang Lyu,et al.  A chaotic micromixer modulated by constructive vortex agitation , 2007 .

[19]  I. Mezić,et al.  Chaotic Mixer for Microchannels , 2002, Science.

[20]  Xudong Cao,et al.  Quantitative characterization of micromixing simulation. , 2008, Biomicrofluidics.

[21]  Tony Jun Huang,et al.  Milliseconds microfluidic chaotic bubble mixer , 2009 .

[22]  Nam-Trung Nguyen,et al.  Micromixers: Fundamentals, Design, and Fabrication , 2008 .

[23]  Kwang-Yong Kim,et al.  Evaluation of the mixing performance of three passive micromixers , 2009 .

[24]  Chih-Yang Wu,et al.  Crosswise ridge micromixers with split and recombination helical flows , 2011 .

[25]  Isabelle Leray,et al.  A novel microfluidic flow-injection analysis device with fluorescence detection for cation sensing. Application to potassium , 2007, Analytical and bioanalytical chemistry.

[26]  Ping-Chiang Lyu,et al.  An overlapping crisscross micromixer , 2007 .

[27]  Che-Hsin Lin,et al.  Microfluidic T-form mixer utilizing switching electroosmotic flow. , 2004, Analytical chemistry.

[28]  Sang-Hyo Kim,et al.  Microfluidic device for bio analytical systems , 2004 .

[29]  Oliver Geschke,et al.  A novel passive micromixer: lamination in a planar channel system , 2010 .

[30]  Minoru Seki,et al.  Development of a passive micromixer based on repeated fluid twisting and flattening, and its application to DNA purification , 2005, Analytical and bioanalytical chemistry.

[31]  Jin-Woo Choi,et al.  A novel in-plane passive microfluidic mixer with modified Tesla structures. , 2004, Lab on a chip.

[32]  D. Sinton,et al.  A sequential injection microfluidic mixing strategy , 2005 .