Superparamagnetic iron oxide (SPIO)‐enhanced liver MRI with ferucarbotran: Efficacy for characterization of focal liver lesions

To evaluate the efficacy of ferucarbotran in T2‐weighted (T2W) fast spin‐echo (FSE) and T2*W gradient‐echo (GRE) sequences for characterizing focal liver lesions.

[1]  M. Taupitz,et al.  SHU 555A. A new superparamagnetic iron oxide contrast agent for magnetic resonance imaging. , 1994, Investigative radiology.

[2]  J. Heiken,et al.  Detection of focal hepatic masses: prospective evaluation with CT, delayed CT, CT during arterial portography, and MR imaging. , 1989, Radiology.

[3]  B. V. Van Beers,et al.  Detection and segmental location of malignant hepatic tumors: comparison of ferumoxides-enhanced gradient-echo and T2-weighted spin-echo MR imaging. , 1997, AJR. American journal of roentgenology.

[4]  C. Bartolozzi,et al.  Focal liver lesions: MR imaging–pathologic correlation , 2001, European Radiology.

[5]  R. Weissleder,et al.  Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. , 1990, Radiology.

[6]  J. V. Engelshoven,et al.  Hepatic adenoma and focal nodular hyperplasia: MR findings with superparamagnetic iron oxide-enhanced MRI. , 1998, Clinical imaging.

[7]  A. Baert,et al.  Detection of liver metastases with superparamagnetic iron oxide in 15 patients: results of MR imaging at 1.5 T. , 1989, AJR. American journal of roentgenology.

[8]  B. Tombach,et al.  Hepatic MRI with SPIO: detection and characterization of focal liver lesions , 1998, European Radiology.

[9]  R. Semelka,et al.  Malignant liver lesions: Comparison of spiral CT arterial portography and MR imaging for diagnostic accuracy, cost, and effect on patient management , 1996, Journal of magnetic resonance imaging : JMRI.

[10]  K. Hughes Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of indications for resection. Registry of Hepatic Metastases. , 1988, Surgery.

[11]  P. Mergo,et al.  Characterization of focal hepatic lesions with ferumoxides-enhanced T2-weighted MR imaging. , 2000, AJR. American journal of roentgenology.

[12]  C. Claussen,et al.  MR imaging of the liver with Resovist: safety, efficacy, and pharmacodynamic properties. , 1997, Radiology.

[13]  M. Taupitz,et al.  Contrast‐enhanced MR imaging of liver and spleen: First experience in humans with a new superparamagnetic iron oxide , 1994, Journal of magnetic resonance imaging : JMRI.

[14]  T. Ichikawa,et al.  Detection of hepatocellular carcinoma and its metastases with various pulse sequences using superparamagnetic iron oxide (SHU-555-A) , 2000, Abdominal Imaging.

[15]  R. Murakami,et al.  Hepatocellular carcinoma in cirrhotic livers: detection with unenhanced and iron oxide-enhanced MR imaging. , 1995, Radiology.

[16]  P. Mergo,et al.  Ring enhancement in ultrasmall superparamagnetic iron oxide MR imaging: a potential new sign for characterization of liver lesions. , 1996, AJR. American journal of roentgenology.

[17]  F. Lazeyras,et al.  Specificity of SPIO particles for characterization of liver hemangiomas using MRI , 2003, Abdominal Imaging.

[18]  C. Bartolozzi,et al.  Abdominal MR: liver and pancreas , 1999, European Radiology.

[19]  D. Rubin,et al.  Differentiation of liver hemangiomas from metastases and hepatocellular carcinoma at MR imaging enhanced with blood-pool contrast agent Code-7227. , 1997, Radiology.

[20]  B. V. Van Beers,et al.  Detection of hepatic metastases: ferumoxides-enhanced MR imaging versus unenhanced MR imaging and CT during arterial portography. , 1996, Radiology.

[21]  C. Marx,et al.  Hepatic lesion detection and characterization: value of nonenhanced MR imaging, superparamagnetic iron oxide-enhanced MR imaging, and spiral CT-ROC analysis. , 2000, Radiology.

[22]  T Berns,et al.  Clinical results with Resovist: a phase 2 clinical trial. , 1995, Radiology.

[23]  V. Servois,et al.  Hepatic tumors: detection and characterization at 1-T MR imaging enhanced with AMI-25. , 1994, Radiology.

[24]  T. Murakami,et al.  Preoperative detection of malignant hepatic tumors: comparison of combined methods of MR imaging with combined methods of CT. , 2000, AJR. American journal of roentgenology.

[25]  D. Khayat,et al.  Liver metastases: safety and efficacy of detection with superparamagnetic iron oxide in MR imaging. , 1994, Radiology.

[26]  Maximization of contrast‐to‐noise ratio to distinguish diffusion and microcirculatory flow , 1991, Journal of magnetic resonance imaging : JMRI.

[27]  M Oudkerk,et al.  Hepatic lesions: detection with ferumoxide-enhanced T1-weighted MR imaging. , 1997, Radiology.

[28]  S. Seltzer,et al.  Imaging hepatic metastases from colorectal carcinoma: identification of candidates for partial hepatectomy. , 1989, AJR. American journal of roentgenology.

[29]  P. Robinson,et al.  Hepatic lesion detection at MR imaging: a comparative study with four sequences. , 1997, Radiology.

[30]  M. Kanematsu,et al.  Malignant hepatic tumor detection with ferumoxides‐enhanced MR imaging with a 1.5‐T system: Comparison of four imaging pulse sequences , 2001, Journal of magnetic resonance imaging : JMRI.

[31]  S. Saini,et al.  T2 relaxation times of hypervascular and non-hypervascular liver lesions: do hypervascular lesions mimic haemangiomas on heavily T2-weighted MR images? , 1996, Clinical radiology.

[32]  Y. Yamashita,et al.  Detection of hepatocellular carcinoma arising in cirrhotic livers: comparison of gadolinium- and ferumoxides-enhanced MR imaging. , 1999, AJR. American journal of roentgenology.

[33]  A. Kaider,et al.  Detection of focal hepatic lesions: Comparison of unenhanced and SHU 555 A‐enhanced MR imaging versus biphasic helical CTAP , 2000, Journal of magnetic resonance imaging : JMRI.

[34]  M. Goldberg,et al.  Hepatic hemangiomas and malignant tumors: improved differentiation with heavily T2-weighted conventional spin-echo MR imaging. , 1994, Radiology.

[35]  D. Elias,et al.  MRI of Liver Metastases from Colorectal Cancer vs. CT during Arterial Portography , 1993, Journal of computer assisted tomography.

[36]  M. Mack,et al.  Magnetic resonance imaging of focal liver lesions. Comparison of the superparamagnetic iron oxide resovist versus gadolinium-DTPA in the same patient. , 1996, Investigative radiology.

[37]  W. Pegios,et al.  Superparamagnetic iron oxide--enhanced versus gadolinium-enhanced MR imaging for differential diagnosis of focal liver lesions. , 1996, Radiology.