CBR for Modeling Complex Systems

This paper describes how CBR can be used to compare, reuse, and adapt inductive models that represent complex systems. Complex systems are not well understood and therefore require models for their manipulation and understanding. We propose an approach to address the challenges for using CBR in this context, which relate to finding similar inductive models (solutions) to represent similar complex systems (problems). The purpose is to improve the modeling task by considering the quality of different models to represent a system based on the similarity to a system that was successfully modeled. The revised and confirmed suitability of a model can become additional evidence of similarity between two complex systems, resulting in an increased understanding of a domain. This use of CBR supports tasks (e.g., diagnosis, prediction) that inductive or mathematical models alone cannot perform. We validate our approach by modeling software systems, and illustrate its potential significance for biological systems.

[1]  Maria Malek,et al.  Hybrid Approaches for Integrating Neural Networks and Case Based Reasoning: From Loosely Coupled to Tightly Coupled Models , 2000, Soft Computing in Case Based Reasoning.

[2]  Isabelle Bichindaritz Mémoire: Case Based Reasoning Meets the Semantic Web in Biology and Medicine , 2004, ECCBR.

[3]  Rosina O. Weber,et al.  Knowledge management for computational intelligence systems , 2004, Eighth IEEE International Symposium on High Assurance Systems Engineering, 2004. Proceedings..

[4]  A Kriete,et al.  Automated Tissue Analysis – a Bioinformatics Perspective , 2005, Methods of Information in Medicine.

[5]  Eva Armengol,et al.  Relational Case-based Reasoning for Carcinogenic Activity Prediction , 2003, Artificial Intelligence Review.

[6]  Abraham Kandel,et al.  The data mining approach to automated software testing , 2003, KDD '03.

[7]  Steven Bogaerts,et al.  Facilitating CBR for Incompletely-Described Cases: Distance Metrics for Partial Problem Descriptions , 2004, ECCBR.

[8]  J. Peters,et al.  Polyunsaturated Fatty Acid Suppression of Hepatic Fatty Acid Synthase and S14 Gene Expression Does Not Require Peroxisome Proliferator-activated Receptor α* , 1997, The Journal of Biological Chemistry.

[9]  W. J. Visek,et al.  Biochemical and Molecular Roles of Nutrients Lipid Level and Type Alter Stearoyl CoA Desaturase mRNA Abundance Differently in Mice with Distinct Susceptibilities to Diet-Influenced Diseases , 1997 .

[10]  Abraham Kandel,et al.  TEST SET GENERATION AND REDUCTION WITH ARTIFICIAL NEURAL NETWORKS , 2004 .

[11]  Sang Chan Park,et al.  Towards Integration of Memory Based Learning and Neural Networks , 2000, Soft Computing in Case Based Reasoning.

[12]  B. Mark Evers,et al.  Age-associated changes in gene expression patterns in the liver , 2002, Journal of Gastrointestinal Surgery.

[13]  Sankar K. Pal,et al.  Soft Computing in Case Based Reasoning , 2000, Springer London.

[14]  I. Kohane,et al.  Gene regulation and DNA damage in the ageing human brain , 2004, Nature.

[15]  R. Rodriguez,et al.  Nutritional genomics: the next frontier in the postgenomic era , 2003 .

[16]  Abraham Kandel,et al.  Artificial intelligence methods in software testing , 2004 .

[17]  Barry Smyth,et al.  Advances in Case-Based Reasoning , 1996, Lecture Notes in Computer Science.

[18]  R Eils,et al.  Informatics United , 2003, Methods of Information in Medicine.

[19]  Barry Smyth,et al.  Experiments On Adaptation-Guided Retrieval In Case-Based Design , 1995, ICCBR.

[20]  B. Ames,et al.  DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. , 2001, Mutation research.

[21]  Thomas Barr,et al.  Architectural overview of the computational intelligence testing tool , 2004, Eighth IEEE International Symposium on High Assurance Systems Engineering, 2004. Proceedings..

[22]  Stephen Welle,et al.  Gene expression profile of aging in human muscle. , 2003, Physiological genomics.

[23]  E. Epel,et al.  Accelerated telomere shortening in response to life stress. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[24]  J. Davies,et al.  Molecular Biology of the Cell , 1983, Bristol Medico-Chirurgical Journal.

[25]  Alexander C McFarlane,et al.  Biologic models of traumatic memories and post-traumatic stress disorder. The role of neural networks. , 2002, The Psychiatric clinics of North America.

[26]  Rosina O. Weber,et al.  Systematically Evolving Configuration Parameters for Computational Intelligence Methods , 2005, PReMI.

[27]  Luc Lamontagne,et al.  Case-Based Reasoning Research and Development , 1997, Lecture Notes in Computer Science.

[28]  Aravinda Chakravarti,et al.  Nature, nurture and human disease , 2003, Nature.

[29]  H Campbell,et al.  Gene–environment interactions—the BioBank UK study , 2002, The Pharmacogenomics Journal.