Deposition of Antimicrobial Copper-Rich Coatings on Polymers by Atmospheric Pressure Jet Plasmas

Inanimate surfaces serve as a permanent reservoir for infectious microorganisms, which is a growing problem in areas in everyday life. Coating of surfaces with inorganic antimicrobials, such as copper, can contribute to reduce the adherence and growth of microorganisms. The use of a DC operated air plasma jet for the deposition of copper thin films on acrylonitrile butadiene styrene (ABS) substrates is reported. ABS is a widespread material used in consumer applications, including hospitals. The influence of gas flow rate and input current on thin film characteristics and its bactericidal effect have been studied. Results from X-ray photoelectron spectroscopy (XPS) and atomic force microscopy confirmed the presence of thin copper layers on plasma-exposed ABS and the formation of copper particles with a size in the range from 20 to 100 nm, respectively. The bactericidal properties of the copper-coated surfaces were tested against Staphylococcus aureus. A reduction in growth by 93% compared with the attachment of bacteria on untreated samples was observed for coverage of the surface with 7 at. % copper.

[1]  D. Briggs,et al.  High Resolution XPS of Organic Polymers: The Scienta ESCA300 Database , 1992 .

[2]  Hughes Rg,et al.  Preventing Health Care–Associated Infections -- Patient Safety and Quality: An Evidence-Based Handbook for Nurses , 2008 .

[3]  Ilker S. Bayer,et al.  Analysis of wear abrasion resistance of superhydrophobic acrylonitrile butadiene styrene rubber (ABS) nanocomposites , 2015 .

[4]  K. Dietz,et al.  The relationship between metal toxicity and cellular redox imbalance. , 2009, Trends in plant science.

[5]  F. Fanelli,et al.  Aerosol-Assisted Atmospheric Pressure Cold Plasma Deposition of Organic–Inorganic Nanocomposite Coatings , 2014, Plasma Chemistry and Plasma Processing.

[6]  J. Kolb,et al.  Nitric Oxide Generation with an Air Operated Non‐Thermal Plasma Jet and Associated Microbial Inactivation Mechanisms , 2014 .

[7]  O. Cerf,et al.  Biofilms and their consequences, with particular reference to hygiene in the food industry. , 1993, The Journal of applied bacteriology.

[8]  M. Schnabelrauch,et al.  Low Temperature Deposition of Antibacterially Active Silicon Oxide Layers Containing Silver Nanoparticles, Prepared by Atmospheric Pressure Plasma Chemical Vapor Deposition , 2013 .

[9]  G. Wang,et al.  Property reinforcement of acrylonitrile-butadiene-styrene by simultaneous incorporation of carbon nanotubes and self-prepared copper particles , 2015 .

[10]  Susan L. Cohen,et al.  Mechanisms of copper chemical vapor deposition , 1992 .

[11]  D. Nečas,et al.  Gwyddion: an open-source software for SPM data analysis , 2012 .

[12]  M. Alagar,et al.  Studies of Copper Nanoparticles Effects on Micro-organisms , 2011, 1110.1372.

[13]  J. Pierson,et al.  Reactive magnetron sputtering of copper, silver, and gold , 2005 .

[14]  R. G. Richards,et al.  An introduction to Staphylococcus aureus, and techniques for identifying and quantifying S. aureus adhesins in relation to adhesion to biomaterials: review. , 2002, European cells & materials.

[15]  J. Kolb,et al.  Cold DC-Operated Air Plasma Jet for the Inactivation of Infectious Microorganisms , 2012, IEEE Transactions on Plasma Science.

[16]  Y. Seo,et al.  Polyetheretherketone (PEEK) surface functionalization by low-energy ion-beam irradiation under a reactive O2 environment and its effect on the PEEK/copper adhesives. , 2004, Langmuir : the ACS journal of surfaces and colloids.

[17]  R. Bader,et al.  Antimicrobial Potential of Copper‐Containing Titanium Surfaces Generated by Ion Implantation and Dual High Power Impulse Magnetron Sputtering , 2012 .

[18]  Lei Song,et al.  Enhanced mechanical, thermal and flame retardant properties by combining graphene nanosheets and metal hydroxide nanorods for Acrylonitrile–Butadiene–Styrene copolymer composite , 2014 .

[19]  J. M. Burkstrand.  Electron spectroscopic study of oxygen‐plasma‐treated polymer surfaces , 1978 .

[20]  Henry F. Chambers,et al.  Waves of resistance: Staphylococcus aureus in the antibiotic era , 2009, Nature Reviews Microbiology.

[21]  J. Kolb,et al.  Discharge Dynamics and Modes of an Atmospheric Pressure Non-Equilibrium Air Plasma Jet , 2013 .

[22]  G. Offergeld,et al.  Characterization of oxygen species adsorbed on copper and nickel oxides by X-ray photoelectron spectroscopy , 1972 .

[23]  K. Hiraoka,et al.  Prevention of the Reduction of CuO during X‐ray Photoelectron Spectroscopy Analysis , 1996 .

[24]  Juergen F. Kolb,et al.  Cold atmospheric pressure air plasma jet for medical applications , 2008 .

[25]  Yi Feng,et al.  Fabrication and Properties of Silver-Doped Acrylonitrile Butadiene Styrene (ABS) Composites , 2013 .

[26]  H. Humphreys,et al.  Application of copper to prevent and control infection. Where are we now? , 2012, The Journal of hospital infection.

[27]  M. Martínez,et al.  Surface modifications of polycarbonate (PC) and acrylonitrile butadiene styrene (ABS) copolymer by treatment with atmospheric plasma , 2009 .

[28]  R. Wilken,et al.  Surface radical analysis on plasma-treated polymers , 1999 .

[29]  P. Levin,et al.  Cell Size Control in Bacteria , 2012, Current Biology.

[30]  A. Vlaicu,et al.  Synthesis of Copper Particles by Non-thermal Atmospheric Pressure Plasma Jet , 2015 .

[31]  K. Weltmann,et al.  Oxygen and Water Plasma‐Immersion Ion Implantation of Copper into Titanium for Antibacterial Surfaces of Medical Implants , 2010 .

[32]  Christopher Rensing,et al.  Metallic Copper as an Antimicrobial Surface , 2010, Applied and Environmental Microbiology.

[33]  S. S. Madaeni,et al.  Fabrication of novel (acrylonitrile butadiene styrene/activated carbon/silver nanoparticles) heterogeneous anion exchange membrane: Physico-chemical and antibacterial characteristics , 2013 .

[34]  Gadi Borkow,et al.  Use of Biocidal Surfaces for Reduction of Healthcare Acquired Infections , 2014, Springer International Publishing.

[35]  A. Kramer,et al.  Survival of Microorganisms on Inanimate Surfaces , 2014, Use of Biocidal Surfaces for Reduction of Healthcare Acquired Infections.

[36]  I. O. Wallinder,et al.  Cell membrane damage and protein interaction induced by copper containing nanoparticles--importance of the metal release process. , 2013, Toxicology.

[37]  Andrea R. Gerson,et al.  Resolving surface chemical states in XPS analysis of first row transition metals, oxides and hydroxides: Sc, Ti, V, Cu and Zn , 2010 .

[38]  R. Lazzaroni,et al.  Characterization of nickel films deposited by cold remote nitrogen plasma on acrylonitrile-butadiene-styrene copolymer , 1995 .

[39]  J. Friedrich,et al.  Adhesion of metals to plasma-induced functional groups at polymer surfaces , 2005 .

[40]  M. Scrocco.  Satellite structure in the x-ray photoelectron spectra of CuO Cu2O , 1979 .

[41]  H. Palza.  Antimicrobial Polymers with Metal Nanoparticles , 2015, International journal of molecular sciences.

[42]  Teresa O'Connor,et al.  Preventing health care-associated infections. , 2009, Nursing New Zealand.

[43]  K. Schoenbach,et al.  Low temperature, atmospheric pressure, direct current microplasma jet operated in air, nitrogen and oxygen , 2010 .

[44]  A. Marchetti,et al.  Economic burden of healthcare-associated infection in US acute care hospitals: societal perspective , 2013, Journal of medical economics.