Extracellular vesicle microRNA transfer in cardiovascular disease.

[1]  L. Elia,et al.  TGFb triggers miR-143/145 transfer from smooth muscle cells to endothelial cells through tunneling nanotubes , 2015 .

[2]  G. Condorelli,et al.  TGFβ Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization. , 2015, Circulation research.

[3]  Yi Jing,et al.  Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs , 2015, Proceedings of the National Academy of Sciences.

[4]  K. Abu-Amero,et al.  Utility of Circulating MicroRNAs as Clinical Biomarkers for Cardiovascular Diseases , 2015, BioMed research international.

[5]  Kristin M. French,et al.  Identification of Therapeutic Covariant MicroRNA Clusters in Hypoxia-Treated Cardiac Progenitor Cell Exosomes Using Systems Biology , 2015, Circulation research.

[6]  Joana A. Vidigal,et al.  In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA , 2015, Proceedings of the National Academy of Sciences.

[7]  L. Maegdefessel,et al.  The emerging role of microRNAs in cardiovascular disease , 2014, Journal of internal medicine.

[8]  Muneesh Tewari,et al.  Quantitative and stoichiometric analysis of the microRNA content of exosomes , 2014, Proceedings of the National Academy of Sciences.

[9]  Mark Ibberson,et al.  Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells. , 2014, Cell reports.

[10]  Joseph C. Wu,et al.  Cross Talk of Combined Gene and Cell Therapy in Ischemic Heart Disease: Role of Exosomal MicroRNA Transfer , 2014, Circulation.

[11]  T. Moccetti,et al.  Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction. , 2014, Cardiovascular research.

[12]  Jiang Chang,et al.  Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells. , 2014, Journal of molecular and cellular cardiology.

[13]  R. Gladstone,et al.  MicroRNA-144 is a circulating effector of remote ischemic preconditioning , 2014, Basic Research in Cardiology.

[14]  Isobel S Okoye,et al.  MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells , 2014, Immunity.

[15]  D. Kass,et al.  Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies. , 2014, Circulation research.

[16]  M. Latronico,et al.  microRNAs in cardiovascular diseases: current knowledge and the road ahead. , 2014, Journal of the American College of Cardiology.

[17]  Toby C. Cornish,et al.  Lessons from miR-143/145: the importance of cell-type localization of miRNAs , 2014, Nucleic acids research.

[18]  A. Maitra,et al.  An Essential Mesenchymal Function for miR-143/145 in Intestinal Epithelial Regeneration , 2014, Cell.

[19]  E. Marbán,et al.  Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy , 2014, Stem cell reports.

[20]  Xiaoke Yin,et al.  Cardiac fibroblast-derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy. , 2014, The Journal of clinical investigation.

[21]  S. Price,et al.  miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export. , 2014, American journal of physiology. Cell physiology.

[22]  Z. Giricz,et al.  Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles. , 2014, Journal of molecular and cellular cardiology.

[23]  Toby C. Cornish,et al.  A Critical Evaluation of microRNA Biomarkers in Non-Neoplastic Disease , 2014, PloS one.

[24]  Wei Huang,et al.  Ischemic Preconditioning Potentiates the Protective Effect of Stem Cells through Secretion of Exosomes by Targeting Mecp2 via miR-22 , 2014, PloS one.

[25]  K. Kelnar,et al.  Quantification of Therapeutic miRNA Mimics in Whole Blood from Nonhuman Primates , 2014, Analytical chemistry.

[26]  Andrew F. Hill,et al.  Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles , 2014, Journal of extracellular vesicles.

[27]  F. Sánchez‐Madrid,et al.  Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs , 2013, Nature Communications.

[28]  Ana Kozomara,et al.  miRBase: annotating high confidence microRNAs using deep sequencing data , 2013, Nucleic Acids Res..

[29]  M. Ashraf,et al.  Cardiomyocyte Protection by GATA-4 Gene Engineered Mesenchymal Stem Cells Is Partially Mediated by Translocation of miR-221 in Microvesicles , 2013, PloS one.

[30]  P. Provost,et al.  Activated platelets can deliver mRNA regulatory Ago2•microRNA complexes to endothelial cells via microparticles. , 2013, Blood.

[31]  E. Kroh,et al.  Plasma Processing Conditions Substantially Influence Circulating microRNA Biomarker Levels , 2013, PloS one.

[32]  Thomas Würdinger,et al.  Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells. , 2013, Blood.

[33]  K. Sliwa,et al.  MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy. , 2013, The Journal of clinical investigation.

[34]  S. Kauppinen,et al.  Treatment of HCV infection by targeting microRNA. , 2013, The New England journal of medicine.

[35]  Yusuke Yoshioka,et al.  Neutral Sphingomyelinase 2 (nSMase2)-dependent Exosomal Transfer of Angiogenic MicroRNAs Regulate Cancer Cell Metastasis , 2013, The Journal of Biological Chemistry.

[36]  T. Lüscher,et al.  AngiomiR-126 expression and secretion from circulating CD34(+) and CD14(+) PBMCs: role for proangiogenic effects and alterations in type 2 diabetics. , 2013, Blood.

[37]  Hugh S Markus,et al.  Circulating MicroRNAs as Novel Biomarkers for Platelet Activation , 2013, Circulation research.

[38]  E. Olson,et al.  MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment. , 2013, The Journal of clinical investigation.

[39]  Lynne T. Bemis,et al.  Standardization of sample collection, isolation and analysis methods in extracellular vesicle research , 2013, Journal of extracellular vesicles.

[40]  E. Olson,et al.  MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles , 2012, Nature Reviews Drug Discovery.

[41]  Ramaroson Andriantsitohaina,et al.  Microparticle release in remote ischemic conditioning mechanism. , 2012, American journal of physiology. Heart and circulatory physiology.

[42]  R. Sachidanandam,et al.  High-throughput assessment of microRNA activity and function using microRNA sensor and decoy libraries , 2012, Nature Methods.

[43]  Sarah J. Wheelan,et al.  Nuclear miRNA Regulates the Mitochondrial Genome in the Heart , 2012, Circulation research.

[44]  E. Murphy,et al.  Does the voltage dependent anion channel modulate cardiac ischemia-reperfusion injury? , 2012, Biochimica et biophysica acta.

[45]  Paul J. Harrison,et al.  Invisible vesicles swarm within the iceberg , 2012, Journal of thrombosis and haemostasis : JTH.

[46]  Mario Medvedovic,et al.  Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1. , 2012, Cardiovascular research.

[47]  M. Tewari,et al.  MicroRNA profiling: approaches and considerations , 2012, Nature Reviews Genetics.

[48]  G. Ronquist,et al.  Cardiomyocyte Microvesicles Contain DNA/RNA and Convey Biological Messages to Target Cells , 2012, PloS one.

[49]  J. Mendell,et al.  MicroRNAs in Stress Signaling and Human Disease , 2012, Cell.

[50]  Achilleas S. Frangakis,et al.  Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs , 2012, Nature Cell Biology.

[51]  Simon C Watkins,et al.  Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. , 2012, Blood.

[52]  E. Olson,et al.  Inhibition of miR-15 Protects Against Cardiac Ischemic Injury , 2012, Circulation research.

[53]  S. Skinner,et al.  Pathogenesis of Lethal Cardiac Arrhythmias in Mecp2 Mutant Mice: Implication for Therapy in Rett Syndrome , 2011, Science Translational Medicine.

[54]  E. Kroh,et al.  Blood Cell Origin of Circulating MicroRNAs: A Cautionary Note for Cancer Biomarker Studies , 2011, Cancer Prevention Research.

[55]  M. Zile,et al.  Relationship Between the Temporal Profile of Plasma microRNA and Left Ventricular Remodeling in Patients After Myocardial Infarction , 2011, Circulation. Cardiovascular genetics.

[56]  O. Kent,et al.  MicroRNA profiling of diverse endothelial cell types , 2011, BMC Medical Genomics.

[57]  D. Cacchiarelli,et al.  miRNAs as serum biomarkers for Duchenne muscular dystrophy , 2011, EMBO molecular medicine.

[58]  Fátima Sánchez-Cabo,et al.  Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells , 2011, Nature communications.

[59]  K. Vickers,et al.  MicroRNAs are Transported in Plasma and Delivered to Recipient Cells by High-Density Lipoproteins , 2011, Nature Cell Biology.

[60]  Jan A Staessen,et al.  Circulating MicroRNA-208b and MicroRNA-499 Reflect Myocardial Damage in Cardiovascular Disease , 2010, Circulation. Cardiovascular genetics.

[61]  M. Mayr,et al.  Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes , 2010, Circulation research.

[62]  Jing Li,et al.  Secreted monocytic miR-150 enhances targeted endothelial cell migration. , 2010, Molecular cell.

[63]  Federica Limana,et al.  Circulating microRNAs are new and sensitive biomarkers of myocardial infarction , 2010, European heart journal.

[64]  T. D. de Gruijl,et al.  Functional delivery of viral miRNAs via exosomes , 2010, Proceedings of the National Academy of Sciences.

[65]  Yue Li,et al.  Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. , 2010, European heart journal.

[66]  M. Hristov,et al.  Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection , 2009, Science Signaling.

[67]  Xiaoying Wang,et al.  Endogenous microRNAs induced by heat‐shock reduce myocardial infarction following ischemia–reperfusion in mice , 2008, FEBS letters.

[68]  Jeffrey E. Thatcher,et al.  Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis , 2008, Proceedings of the National Academy of Sciences.

[69]  Daniel B. Martin,et al.  Circulating microRNAs as stable blood-based markers for cancer detection , 2008, Proceedings of the National Academy of Sciences.

[70]  S. Boyd Everything you wanted to know about small RNA but were afraid to ask , 2008, Laboratory Investigation.

[71]  A. Mügge,et al.  Circulating endothelial microparticles correlate inversely with endothelial function in patients with ischemic left ventricular dysfunction. , 2008, Journal of cardiac failure.

[72]  C. Sander,et al.  A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing , 2007, Cell.

[73]  A. Knowlton,et al.  HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway. , 2007, American journal of physiology. Heart and circulatory physiology.

[74]  J. Lötvall,et al.  Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells , 2007, Nature Cell Biology.

[75]  Stefan Neubauer,et al.  The failing heart--an engine out of fuel. , 2007, The New England journal of medicine.

[76]  K. Sliwa,et al.  A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy , 2007, Cell.

[77]  E. Olson,et al.  A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure , 2006, Proceedings of the National Academy of Sciences.

[78]  Nikos Werner,et al.  Circulating CD31+/Annexin V+ Apoptotic Microparticles Correlate With Coronary Endothelial Function in Patients With Coronary Artery Disease , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[79]  G. Lip,et al.  Platelet microparticles and soluble P selectin in peripheral artery disease: Relationship to extent of disease and platelet activation markers , 2005, Annals of medicine.

[80]  D. Bartel MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[81]  P. Sharp,et al.  Embryonic stem cell-specific MicroRNAs. , 2003, Developmental cell.

[82]  P. Libby,et al.  Inflammation and Atherosclerosis , 2002, Circulation.

[83]  H. Zoghbi,et al.  Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 , 1999, Nature Genetics.

[84]  R. Pakala,et al.  Platelet microparticles promote platelet interaction with subendothelial matrix in a glycoprotein IIb/IIIa-dependent mechanism. , 1999, Circulation.

[85]  G. FitzGerald,et al.  Modulation of monocyte-endothelial cell interactions by platelet microparticles. , 1998, The Journal of clinical investigation.

[86]  R. Kloner,et al.  Regional Ischemic 'Preconditioning' Protects Remote Virgin Myocardium From Subsequent Sustained Coronary Occlusion , 1993, Circulation.

[87]  R. Jennings,et al.  Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. , 1986, Circulation.

[88]  Hanlin Gao,et al.  UC Office of the President Recent Work Title Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis , 2014 .

[89]  Harsh Dweep,et al.  miRWalk database for miRNA-target interactions. , 2014, Methods in molecular biology.