ATM polymorphisms are associated with risk of radiation-induced pneumonitis.

[1]  Lujun Zhao,et al.  Elevation of plasma TGF-beta1 during radiation therapy predicts radiation-induced lung toxicity in patients with non-small-cell lung cancer: a combined analysis from Beijing and Michigan. , 2009, International journal of radiation oncology, biology, physics.

[2]  W. Tan,et al.  Characterization of Functional Excision Repair Cross-Complementation Group 1 Variants and Their Association with Lung Cancer Risk and Prognosis , 2008, Clinical Cancer Research.

[3]  Hubert Thierens,et al.  Predicting risk of radiation-induced lung injury. , 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[4]  Wen Tan,et al.  Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. , 2007, Carcinogenesis.

[5]  M. Dewhirst,et al.  Predicting lung radiotherapy-induced pneumonitis using a model combining parametric Lyman probit with nonparametric decision trees. , 2007, International journal of radiation oncology, biology, physics.

[6]  Z. Liao,et al.  Radiochemotherapy of esophageal cancer. , 2007, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

[7]  Peng Liu,et al.  Genetic polymorphisms and treatment response in advanced non-small cell lung cancer. , 2007, Lung cancer.

[8]  Debra H Brinkmann,et al.  Incidence of radiation pneumonitis after thoracic irradiation: Dose-volume correlates. , 2007, International journal of radiation oncology, biology, physics.

[9]  M. Koukourakis,et al.  Radiation pneumonitis and fibrosis: mechanisms underlying its pathogenesis and implications for future research. , 2006, International journal of radiation oncology, biology, physics.

[10]  M. Anscher,et al.  Does transforming growth factor-beta1 predict for radiation-induced pneumonitis in patients treated for lung cancer? , 2006, Cytokine.

[11]  R. Stock,et al.  Genetic predictors of adverse radiotherapy effects: the Gene-PARE project. , 2006, International journal of radiation oncology, biology, physics.

[12]  J. Couzin.  The HapMap Gold Rush: Researchers Mine a Rich Deposit , 2006, Science.

[13]  J. Deasy,et al.  Modeling radiation pneumonitis risk with clinical, dosimetric, and spatial parameters. , 2006, International journal of radiation oncology, biology, physics.

[14]  Jens Overgaard,et al.  ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy. , 2006, International journal of radiation oncology, biology, physics.

[15]  J. Weinstein,et al.  Biomarkers in Cancer Staging, Prognosis and Treatment Selection , 2005, Nature Reviews Cancer.

[16]  V. Mehta.  Radiation pneumonitis and pulmonary fibrosis in non-small-cell lung cancer: pulmonary function, prediction, and prevention. , 2005, International journal of radiation oncology, biology, physics.

[17]  J. Chang-Claude,et al.  Association between Polymorphisms in the DNA Repair Genes, XRCC1, APE1, and XPD and Acute Side Effects of Radiotherapy in Breast Cancer Patients , 2005, Clinical Cancer Research.

[18]  L. Marks,et al.  Challenges in defining radiation pneumonitis in patients with lung cancer. , 2005, International journal of radiation oncology, biology, physics.

[19]  C. Langston,et al.  Interstitial lung disease in patients with ataxia‐telangiectasia , 2005, Pediatric pulmonology.

[20]  Avraham Eisbruch,et al.  Non-small cell lung cancer therapy-related pulmonary toxicity: an update on radiation pneumonitis and fibrosis. , 2005, Seminars in oncology.

[21]  M. Fernet,et al.  Genetic biomarkers of therapeutic radiation sensitivity. , 2004, DNA repair.

[22]  D. Cox,et al.  ATM haplotypes and cellular response to DNA damage: association with breast cancer risk and clinical radiosensitivity. , 2003, Cancer research.

[23]  R. Gatti,et al.  Improved diagnostic testing for ataxia-telangiectasia by immunoblotting of nuclear lysates for ATM protein expression. , 2003, Molecular genetics and metabolism.

[24]  N. Gueven,et al.  Site‐directed mutagenesis of the ATM promoter: Consequences for response to proliferation and ionizing radiation , 2003, Genes, chromosomes & cancer.

[25]  M. Anscher,et al.  Radiation-induced lung injury. , 2003, Seminars in radiation oncology.

[26]  E. Hall,et al.  Radiation-induced second cancers: the impact of 3D-CRT and IMRT. , 2003, International journal of radiation oncology, biology, physics.

[27]  Y. Shiloh.  ATM and related protein kinases: safeguarding genome integrity , 2003, Nature Reviews Cancer.

[28]  M. Kastan,et al.  DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation , 2003, Nature.

[29]  Jen‐Hau Chen,et al.  Outcome and prognostic factors for patients with non-small-cell lung cancer and severe radiation pneumonitis. , 2002, International journal of radiation oncology, biology, physics.

[30]  J. Overgaard,et al.  Does variability in normal tissue reactions after radiotherapy have a genetic basis--where and how to look for it? , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[31]  M. Villalobos,et al.  Individualization of radiotherapy in breast cancer patients: possible usefulness of a DNA damage assay to measure normal cell radiosensitivity. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[32]  U. Lehmann,et al.  Real-time PCR analysis of DNA and RNA extracted from formalin-fixed and paraffin-embedded biopsies. , 2001, Methods.

[33]  N. Saijo,et al.  Radiation pneumonitis in lung cancer patients: a retrospective study of risk factors and the long-term prognosis. , 2001, International journal of radiation oncology, biology, physics.

[34]  K. Khanna,et al.  DNA double-strand breaks: signaling, repair and the cancer connection , 2001, Nature Genetics.

[35]  Y. Shiloh,et al.  ATM: from gene to function. , 1998, Human molecular genetics.

[36]  T. Stankovic,et al.  A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies. , 1996, Human molecular genetics.

[37]  N. Nomura,et al.  Identification and characterization of a new gene physically linked to the ATM gene. , 1996, Genome research.

[38]  D. Gandara,et al.  Radiation pneumonitis following combined modality therapy for lung cancer: analysis of prognostic factors. , 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[39]  M. Lovett,et al.  A single ataxia telangiectasia gene with a product similar to PI-3 kinase. , 1995, Science.

[40]  D. Weeks,et al.  Assessment of chronic gamma radiosensitivity as an in vitro assay for heterozygote identification of ataxia-telangiectasia. , 1991, Radiation research.

[41]  R. Parshad,et al.  CARRIER DETECTION IN ATAXIA-TELANGIECTASIA , 1986, The Lancet.

[42]  D. Trichopoulos,et al.  T LYMPHOCYTES IN HBAg CARRIERS AND RESPONDERS , 1975, The Lancet.

[43]  J. L. Morgan,et al.  Radiation reaction in ataxia telangiectasia. , 1968, American journal of diseases of children.

[44]  S. Gotoff,et al.  Ataxia Telangiectasia: Neoplasia, Untoward Response to X -Irradiation, and Tuberous Sclerosis , 1967 .

[45]  T. Dörk,et al.  Characterization of ATM gene mutations in 66 ataxia telangiectasia families. , 1999, Human molecular genetics.

[46]  C. Carrie,et al.  2214 Correlation between dose volume histograms, pulmonary function tests and radio-induced pneumonitis in nonsmall cell lung cancer after 3 dimensional radiation therapy , 1999 .

[47]  M. Paterson,et al.  Cellular hypersensitivity to chronic gamma-radiation in cultured fibroblasts from ataxia-telangiectasia heterozygotes. , 1985, Kroc Foundation series.