Mindful attention promotes control of brain network dynamics for self-regulation and discontinues the past from the present

Significance Practicing mindfulness helps individuals regulate attention, thoughts, feelings, and behavior. In recognizing these benefits, various schools, workplaces, and clinics are increasingly teaching mindfulness. How does mindful attention change brain function to support self-regulation? Addressing this question could inform how we teach mindfulness and whom we expect to benefit. We modeled the defining components of mindful experience using tools that probe the structure and function of the brain’s network. In a randomized controlled study of alcohol consumption, we found that a brain network’s dynamic shape predicts individuals’ future alcohol consumption and explains otherwise elusive components of mindful experience, such as being present. Our results provide new understanding of how mindful attention affects brain function.