Tocopherol as plant protector: an overview of Tocopherol biosynthesis enzymes and their role as antioxidant and signaling molecules

[1]  M. Irfan,et al.  Indigenous Tocopherol Improves Tolerance of Oilseed Rape to Cadmium Stress , 2020, Frontiers in Plant Science.

[2]  M. Hartmann,et al.  A Role for Tocopherol Biosynthesis in Arabidopsis Basal Immunity to Bacterial Infection1  [OPEN]. , 2019, Plant physiology.

[3]  S. Munné-Bosch,et al.  Vitamin E in Plants: Biosynthesis, Transport, and Function. , 2019, Trends in plant science.

[4]  Y. Qi,et al.  Chloroplast-to-Nucleus Signaling Regulates MicroRNA Biogenesis in Arabidopsis. , 2019, Developmental cell.

[5]  A. Stocker,et al.  A Tomato Tocopherol-Binding Protein Sheds Light on Intracellular &agr;-Tocopherol Metabolism in Plants , 2018, Plant & cell physiology.

[6]  S. Munné-Bosch,et al.  An altered tocopherol composition in chloroplasts reduces plant resistance to Botrytis cinerea. , 2018, Plant physiology and biochemistry : PPB.

[7]  Jianbing Yan,et al.  Beyond pathways: genetic dissection of tocopherol content in maize kernels by combining linkage and association analyses , 2018, Plant biotechnology journal.

[8]  Xiaomei Zhu,et al.  Rice tocopherol deficiency 1 encodes a homogentisate phytyltransferase essential for tocopherol biosynthesis and plant development in rice , 2018, Plant Cell Reports.

[9]  J. M. Alonso,et al.  Genotypic and Environmental Effects on Tocopherol Content in Almond , 2018, Antioxidants.

[10]  Laurent Mène-Saffrané.  Vitamin E Biosynthesis and Its Regulation in Plants , 2017, Antioxidants.

[11]  S. Kumari,et al.  Comparative Analysis of Tocopherol Biosynthesis Genes and Its Transcriptional Regulation in Soybean Seeds. , 2017, Journal of agricultural and food chemistry.

[12]  C. Jung,et al.  Recent Advances in our Understanding of Tocopherol Biosynthesis in Plants: An Overview of Key Genes, Functions, and Breeding of Vitamin E Improved Crops , 2017, Antioxidants.

[13]  P. Dörmann,et al.  Essential role for phytol kinase and tocopherol in tolerance to combined light and temperature stress in tomato , 2017, Journal of experimental botany.

[14]  F. Virgili,et al.  Tocotrienols: A Family of Molecules with Specific Biological Activities , 2017, Antioxidants.

[15]  Laurent Méné-Saffrané,et al.  Metabolic Origins and Transport of Vitamin E Biosynthetic Precursors , 2017, Front. Plant Sci..

[16]  Vidhu A. Sane,et al.  Tocopherol levels in different mango varieties correlate with MiHPPD expression and its over-expression elevates tocopherols in transgenic Arabidopsis and tomato , 2017, 3 Biotech.

[17]  I. Chung,et al.  Assessment of the phenolic profile, antimicrobial activity and oxidative stability of transgenic Perilla frutescens L.overexpressing tocopherol methyltransferase (γ-tmt) gene. , 2017, Plant physiology and biochemistry : PPB.

[18]  A. Azzi.  Many tocopherols, one vitamin E. , 2017, Molecular aspects of medicine.

[19]  José Antonio Cayuela,et al.  Sorting olive oil based on alpha-tocopherol and total tocopherol content using near-infra-red spectroscopy (NIRS) analysis , 2017 .

[20]  A. Kasperczyk,et al.  α-Tocopherol supplementation and the oxidative stress, homocysteine, and antioxidants in lead exposure , 2017, Archives of environmental & occupational health.

[21]  B. Grimm,et al.  LIL3, a Light-Harvesting Complex Protein, Links Terpenoid and Tetrapyrrole Biosynthesis in Arabidopsis thaliana1[OPEN] , 2017, Plant Physiology.

[22]  Laurent Méné-Saffrané,et al.  Current strategies for vitamin E biofortification of crops. , 2017, Current opinion in biotechnology.

[23]  P. Górnaś,et al.  Cold-pressed and hot-pressed rapeseed oil: The effects of roasting and seed moisture on the antioxi- dant activity, canolol, and tocopherol level. , 2017, Acta scientiarum polonorum. Technologia alimentaria.

[24]  B. Dinler,et al.  Alpha-Tocopherol-Dependent Salt Tolerance is More Related with Auxin Synthesis Rather Than Enhancement Antioxidant Defense in Soybean Roots , 2017, Acta biologica Hungarica.

[25]  A. Ausili,et al.  The vertical location of α-tocopherol in phosphatidylcholine membranes is not altered as a function of the degree of unsaturation of the fatty acyl chains. , 2017, Physical chemistry chemical physics : PCCP.

[26]  S. Munné-Bosch,et al.  Enhanced plastochromanol-8 accumulation during reiterated drought in maize (Zea mays L.). , 2017, Plant physiology and biochemistry : PPB.

[27]  I. Rajcan,et al.  Molecular mapping of soybean seed tocopherols in the cross ‘OAC Bayfield’ × ‘OAC Shire’ , 2017 .

[28]  A. Siger,et al.  Antioxidant (Tocopherol and Canolol) Content in Rapeseed Oil Obtained from Roasted Yellow-Seeded Brassica napus , 2016, Journal of the American Oil Chemists' Society.

[29]  M. Karttunen,et al.  Alpha-tocopherol inhibits pore formation in oxidized bilayers. , 2016, Physical chemistry chemical physics : PCCP.

[30]  Xuemin Wang,et al.  Overexpression of Medicago sativa TMT elevates the α-tocopherol content in Arabidopsis seeds, alfalfa leaves, and delays dark-induced leaf senescence. , 2016, Plant science : an international journal of experimental plant biology.

[31]  K. Yeum,et al.  Genetic variation of carotenoids, vitamin E and phenolic compounds in Provitamin A biofortified maize. , 2016, Journal of the science of food and agriculture.

[32]  L. Freschi,et al.  Pheophytinase Knockdown Impacts Carbon Metabolism and Nutraceutical Content Under Normal Growth Conditions in Tomato. , 2016, Plant & cell physiology.

[33]  F. Carrari,et al.  Down-regulation of tomato PHYTOL KINASE strongly impairs tocopherol biosynthesis and affects prenyllipid metabolism in an organ-specific manner , 2015, Journal of experimental botany.

[34]  Jacob J. Kinnun,et al.  α-Tocopherol Is Well Designed to Protect Polyunsaturated Phospholipids: MD Simulations. , 2015, Biophysical journal.

[35]  A. Weber,et al.  Remobilization of Phytol from Chlorophyll Degradation Is Essential for Tocopherol Synthesis and Growth of Arabidopsis , 2015, Plant Cell.

[36]  Kevin P. Smith,et al.  Quantitative Trait Loci Associated with the Tocochromanol (Vitamin E) Pathway in Barley , 2015, PloS one.

[37]  A. El-Murr,et al.  Nephroprotective and antioxidant significance of selenium and α-tocopherol on lead acetate-induced toxicity of Nile Tilapia (Oreochromis niloticus) , 2015, Fish Physiology and Biochemistry.

[38]  Shuangxia Jin,et al.  Expression of γ-tocopherol methyltransferase in chloroplasts results in massive proliferation of the inner envelope membrane and decreases susceptibility to salt and metal-induced oxidative stresses by reducing reactive oxygen species. , 2014, Plant biotechnology journal.

[39]  Q. Jiang.  Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy. , 2014, Free radical biology & medicine.

[40]  I. Shamsi,et al.  Response of seed tocopherols in oilseed rape to nitrogen fertilizer sources and application rates , 2014, Journal of Zhejiang University SCIENCE B.

[41]  C. Jung,et al.  A Candidate Gene-Based Association Study of Tocopherol Content and Composition in Rapeseed (Brassica napus) , 2012, Front. Plant Sci..

[42]  S. Munné-Bosch,et al.  Accumulation of γ- rather than α-tocopherol alters ethylene signaling gene expression in the vte4 mutant of Arabidopsis thaliana. , 2011, Plant & cell physiology.

[43]  G. Bánhegyi,et al.  Enhanced activity of galactono-1,4-lactone dehydrogenase and ascorbate-glutathione cycle in mitochondria from complex III deficient Arabidopsis. , 2011, Plant physiology and biochemistry : PPB.

[44]  Sijie He,et al.  The role of tocopherol cyclase in salt stress tolerance of rice (Oryza sativa) , 2011, Science China Life Sciences.

[45]  M. Hamberg,et al.  Emerging Complexity in Reactive Oxygen Species Production and Signaling during the Response of Plants to Pathogens1 , 2010, Plant Physiology.

[46]  Govindjee,et al.  Overexpression of gamma-tocopherol methyl transferase gene in transgenic Brassica juncea plants alleviates abiotic stress: physiological and chlorophyll a fluorescence measurements. , 2010, Biochimica et biophysica acta.

[47]  D. DellaPenna,et al.  Mutations of the ER to plastid lipid transporters TGD1, 2, 3 and 4 and the ER oleate desaturase FAD2 suppress the low temperature-induced phenotype of Arabidopsis tocopherol-deficient mutant vte2. , 2010, The Plant journal : for cell and molecular biology.

[48]  D. DellaPenna,et al.  Biosynthesis, regulation and functions of tocochromanols in plants. , 2010, Plant physiology and biochemistry : PPB.

[49]  V. Böhm,et al.  In vitro antioxidant activity of tocopherols and tocotrienols and comparison of vitamin E concentration and lipophilic antioxidant capacity in human plasma. , 2010, Molecular nutrition & food research.

[50]  S. Munné-Bosch,et al.  Tocochromanol functions in plants: antioxidation and beyond. , 2010, Journal of experimental botany.

[51]  S. Munné-Bosch,et al.  Physiological and molecular responses of the isoprenoid biosynthetic pathway in a drought-resistant Mediterranean shrub, Cistus creticus exposed to water deficit. , 2009, Journal of plant physiology.

[52]  S. Munné-Bosch,et al.  Photo- and antioxidant protection and salicylic acid accumulation during post-anthesis leaf senescence in Salvia lanigera grown under Mediterranean climate. , 2007, Physiologia plantarum.

[53]  Edward E. Farmer,et al.  Plant biology: Jasmonate perception machines , 2007, Nature.

[54]  A. A. Gotor,et al.  Determination of tocopherols and phytosterols in sunflower seeds by NIR spectrometry , 2007 .

[55]  U. Sonnewald,et al.  Specific Roles of α- and γ-Tocopherol in Abiotic Stress Responses of Transgenic Tobacco1[W][OA] , 2007, Plant Physiology.

[56]  S. Munné-Bosch,et al.  α-Tocopherol may influence cellular signaling by modulating jasmonic acid levels in plants , 2007, Planta.

[57]  Y. Guisez,et al.  Accumulation of tocopherols and tocotrienols during seed development of grape (Vitis vinifera L. cv. Albert Lavallée). , 2006, Plant physiology and biochemistry : PPB.

[58]  G. Csucs,et al.  Tocopherol Cyclase (VTE1) Localization and Vitamin E Accumulation in Chloroplast Plastoglobule Lipoprotein Particles* , 2006, Journal of Biological Chemistry.

[59]  P. Rey,et al.  Vitamin E Protects against Photoinhibition and Photooxidative Stress in Arabidopsis thaliana , 2005, The Plant Cell Online.

[60]  F. Moshiri,et al.  Metabolically engineered oilseed crops with enhanced seed tocopherol. , 2005, Metabolic engineering.

[61]  S. Munné-Bosch,et al.  The role of α-tocopherol in plant stress tolerance , 2005 .

[62]  Nicholas Smirnoff,et al.  Antioxidants and reactive oxygen species in plants , 2005 .

[63]  D. Bryant,et al.  Tocopherols Protect Synechocystis sp. Strain PCC 6803 from Lipid Peroxidation1 , 2005, Plant Physiology.

[64]  U. Sonnewald,et al.  RNAi-Mediated Tocopherol Deficiency Impairs Photoassimilate Export in Transgenic Potato Plants1 , 2004, Plant Physiology.

[65]  M. Pollard,et al.  Vitamin E Is Essential for Seed Longevity and for Preventing Lipid Peroxidation during Germination , 2004, The Plant Cell Online.

[66]  R. Bruni,et al.  Tocopherols, fatty acids and sterols in seeds of four Sardinian wild Euphorbia species. , 2003, Fitoterapia.

[67]  E. Cahoon,et al.  Characterization of Tocopherol Cyclases from Higher Plants and Cyanobacteria. Evolutionary Implications for Tocopherol Synthesis and Function1 , 2003, Plant Physiology.

[68]  A. Minihane,et al.  Regulation of cell signalling by vitamin E , 2002, Proceedings of the Nutrition Society.

[69]  D. DellaPenna,et al.  Overexpression of the enzyme p-hydroxyphenolpyruvate dioxygenase in Arabidopsis and its relation to tocopherol biosynthesis , 2002 .

[70]  H. Holländer-Czytko,et al.  Jasmonate is involved in the induction of tyrosine aminotransferase and tocopherol biosynthesis in Arabidopsis thaliana , 2002, Planta.

[71]  G. Pastori,et al.  Common Components, Networks, and Pathways of Cross-Tolerance to Stress. The Central Role of “Redox” and Abscisic Acid-Mediated Controls1 , 2002, Plant Physiology.

[72]  C. Shewmaker,et al.  Isolation and Characterization of Homogentisate Phytyltransferase Genes from Synechocystis sp. PCC 6803 and Arabidopsis , 2002, Plant Physiology.

[73]  D. DellaPenna,et al.  The role of 2‐methyl‐6‐phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803 , 2002, FEBS letters.

[74]  S. Munné-Bosch,et al.  The Function of Tocopherols and Tocotrienols in Plants , 2002 .

[75]  P. Beyer,et al.  A novel phytyltransferase from Synechocystis sp. PCC 6803 involved in tocopherol biosynthesis , 2001, FEBS letters.

[76]  Y. Arai,et al.  Antioxidant activities of tocopherols , 2001 .

[77]  R. G. Ackman,et al.  Properties of α-, γ-, and δ-tocopherol in purified fish oil triacylglycerols , 2001 .

[78]  B. Ames,et al.  γ-Tocopherol and its major metabolite, in contrast to α-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells , 2000 .

[79]  A. Stocker,et al.  Vitamin E: non-antioxidant roles. , 2000, Progress in lipid research.

[80]  R. Brigelius-Flohé,et al.  Vitamin E: function and metabolism , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[81]  Xin Eric Wang,et al.  Vitamin E and its function in membranes. , 1999, Progress in lipid research.

[82]  Grusak.  Genomics-assisted plant improvement to benefit human nutrition and health. , 1999, Trends in plant science.

[83]  D. DellaPenna,et al.  Elevating the vitamin E content of plants through metabolic engineering. , 1998, Science.

[84]  A. Girotti.  Lipid hydroperoxide generation, turnover, and effector action in biological systems. , 1998, Journal of lipid research.

[85]  Yolanda Arango,et al.  Localization of α-tocopherol synthesis in chromoplast envelope membranes of Capsicum annuum L. fruits , 1998 .

[86]  Jörg Schwender,et al.  Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate‐independent pathway , 1997, FEBS letters.

[87]  Lars-Åke Appelqvist,et al.  The chemistry and antioxidant properties of tocopherols and tocotrienols , 1996, Lipids.

[88]  Nicholas Smirnoff,et al.  The role of active oxygen in the response of plants to water deficit and desiccation. , 1993, The New phytologist.

[89]  M. Fryer.  The antioxidant effects of thylakoid Vitamin E (α‐tocopherol) , 1992 .

[90]  K. Fukuzawa,et al.  Antioxidant activities of tocopherols on Fe2+-ascorbate-induced lipid peroxidation in lecithin liposomes , 1982, Lipids.

[91]  H. Lichtenthaler,et al.  Localization of prenylquinones in the envelope of spinach chloroplasts. , 1981, Biochimica et biophysica acta.

[92]  R. Ward,et al.  Relative antioxidant activities of the seven tocopherols , 1959 .

[93]  K. Fromm,et al.  WRINKLED1 and ACYL-COA:DIACYLGLYCEROL ACYLTRANSFERASE1 regulate tocochromanol metabolism in Arabidopsis. , 2018, The New phytologist.

[94]  S. Lorkowski,et al.  Vitamin E: Emerging aspects and new directions , 2017, Free radical biology & medicine.

[95]  H. Matsumoto,et al.  Lipid peroxidation is an early symptom triggered by aluminum, but not the primary cause of elongation inhibition in pea roots. , 2001, Plant physiology.

[96]  R. Larson.  The antioxidants of higher plants , 1988 .

[97]  B. F. Daubert,et al.  Delta-tocopherol as an antioxidant in lard , 1948 .