Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR
暂无分享,去创建一个
D. Craik | Q. Kaas | A. Nicke | G. King | R. Clark | S. Dutertre | Julien Giribaldi | V. Herzig | R. Anangi | Xiaosa Wu | Yamina El Hamdaoui
[1] U. Maskos,et al. Role of the Nicotinic Acetylcholine Receptor Chrna5 Gene Mutation in Chronic Obstructive Pulmonary Disease , 2020 .
[2] D. Craik,et al. Stoichiometry dependent inhibition of rat &agr;3&bgr;4 nicotinic acetylcholine receptor by the ribbon isomer of &agr;‐conotoxin AuIB , 2018, Biochemical pharmacology.
[3] C. Enjalbal,et al. Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus , 2018, Toxins.
[4] R. M. Walsh,et al. Structural principles of distinct assemblies of the human alpha 4 beta 2 nicotinic receptor. , 2018 .
[5] R. M. Walsh,et al. Structural principles of distinct assemblies of the human α4β2 nicotinic receptor , 2018, Nature.
[6] J. McIntosh,et al. Nicotinic acetylcholine receptors in neuropathic and inflammatory pain , 2018, FEBS letters.
[7] K. Lindorff-Larsen,et al. How well do force fields capture the strength of salt bridges in proteins? , 2018, bioRxiv.
[8] Jinpeng Yu,et al. Expression in Escherichia coli of fusion protein comprising α‐conotoxin TxIB and preservation of selectivity to nicotinic acetylcholine receptors in the purified product , 2018, Chemical biology & drug design.
[9] S. Dutertre,et al. α-Conotoxins to explore the molecular, physiological and pathophysiological functions of neuronal nicotinic acetylcholine receptors , 2017, Neuroscience Letters.
[10] A. Nicke,et al. Nicotinic acetylcholine receptor inhibitors derived from snake and snail venoms , 2017, Neuropharmacology.
[11] Richard Bonneau,et al. Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models , 2017, Proceedings of the National Academy of Sciences.
[12] Mengsen Li,et al. Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs , 2016, Marine drugs.
[13] D. Craik,et al. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High-Voltage-Activated Calcium Channels via GABA(B) Receptor Activation Reveal a Minimal Functional Motif. , 2016, Angewandte Chemie.
[14] M. Zieliński,et al. Expression of recombinant human bifunctional peptidylglycine α-amidating monooxygenase in CHO cells and its use for insulin analogue modification. , 2016, Protein expression and purification.
[15] Jinpeng Yu,et al. Recombinant Expression and Characterization of α-Conotoxin LvIA in Escherichia coli , 2016, Marine drugs.
[16] S. Jayakar,et al. Orthosteric and Allosteric Ligands of Nicotinic Acetylcholine Receptors for Smoking Cessation , 2015, Front. Mol. Neurosci..
[17] M. Christie,et al. Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management? , 2015, Toxins.
[18] Uwe Maskos,et al. Role of the nicotinic acetylcholine receptor in Alzheimer's disease pathology and treatment , 2015, Neuropharmacology.
[19] J. Yakel,et al. Nicotinic ACh receptors as therapeutic targets in CNS disorders. , 2015, Trends in pharmacological sciences.
[20] M. Antoniewicz. Methods and advances in metabolic flux analysis: a mini-review , 2015, Journal of Industrial Microbiology & Biotechnology.
[21] D. Craik,et al. Discovery, synthesis, and structure-activity relationships of conotoxins. , 2014, Chemical reviews.
[22] D. Craik,et al. A novel α4/7‐conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[23] Jinpeng Yu,et al. Influence of Disulfide Connectivity on Structure and Bioactivity of α-Conotoxin TxIA , 2014, Molecules.
[24] M. Yandell,et al. Characterization of the peptidylglycine α-amidating monooxygenase (PAM) from the venom ducts of neogastropods, Conus bullatus and Conus geographus. , 2013, Toxicon : official journal of the International Society on Toxinology.
[25] A. Bax,et al. Protein backbone and sidechain torsion angles predicted from NMR chemical shifts using artificial neural networks , 2013, Journal of Biomolecular NMR.
[26] G. King,et al. Production of Recombinant Disulfide-Rich Venom Peptides for Structural and Functional Analysis via Expression in the Periplasm of E. coli , 2013, PloS one.
[27] Brian D. Weitzner,et al. Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE) , 2013, PloS one.
[28] A. M. Phillips,et al. Oxidative folding and preparation of α‐conotoxins for use in high‐throughput structure–activity relationship studies , 2013, Journal of peptide science : an official publication of the European Peptide Society.
[29] H. Grubmüller,et al. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit , 2012, Molecular Pharmacology.
[30] Holger Gohlke,et al. MMPBSA.py: An Efficient Program for End-State Free Energy Calculations. , 2012, Journal of chemical theory and computation.
[31] A. Steiner,et al. Modulation of Conotoxin Structure and Function Is Achieved through a Multienzyme Complex in the Venom Glands of Cone Snails* , 2012, The Journal of Biological Chemistry.
[32] G. King,et al. Functional Expression in Escherichia coli of the Disulfide-Rich Sea Anemone Peptide APETx2, a Potent Blocker of Acid-Sensing Ion Channel 3 , 2012, Marine drugs.
[33] Vladimir B. Bajic,et al. Conotoxins that Confer Therapeutic Possibilities , 2012, Marine drugs.
[34] D. Yoshikami,et al. Selective Purification of Recombinant Neuroactive Peptides Using the Flagellar Type III Secretion System , 2012, mBio.
[35] Quentin Kaas,et al. Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor. , 2012, The journal of physical chemistry. B.
[36] David J. Craik,et al. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database , 2011, Nucleic Acids Res..
[37] David J. Craik,et al. Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations , 2011, PLoS Comput. Biol..
[38] D. Baker,et al. Alternate states of proteins revealed by detailed energy landscape mapping. , 2011, Journal of molecular biology.
[39] Nir London,et al. Sub‐angstrom modeling of complexes between flexible peptides and globular proteins , 2010, Proteins.
[40] D. Craik,et al. Conopeptide characterization and classifications: an analysis using ConoServer. , 2010, Toxicon : official journal of the International Society on Toxinology.
[41] David John Adams,et al. α-Conotoxin AuIB Isomers Exhibit Distinct Inhibitory Mechanisms and Differential Sensitivity to Stoichiometry of α3β4 Nicotinic Acetylcholine Receptors* , 2010, The Journal of Biological Chemistry.
[42] R. Dror,et al. Improved side-chain torsion potentials for the Amber ff99SB protein force field , 2010, Proteins.
[43] D. Bertrand,et al. Interaction of α‐conotoxin ImII and its analogs with nicotinic receptors and acetylcholine‐binding proteins: additional binding sites on Torpedo receptor , 2009, Journal of neurochemistry.
[44] A. Bax,et al. TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts , 2009, Journal of biomolecular NMR.
[45] J. McIntosh,et al. Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors , 2009, Acta Pharmacologica Sinica.
[46] D. Craik,et al. Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics , 2007, BMC Structural Biology.
[47] M. Parrinello,et al. Canonical sampling through velocity rescaling. , 2007, The Journal of chemical physics.
[48] A. Sali,et al. Statistical potential for assessment and prediction of protein structures , 2006, Protein science : a publication of the Protein Society.
[49] R. Kini,et al. Effect of C-Terminal Amidation on Folding and Disulfide-Pairing of α-Conotoxin ImI† , 2005 .
[50] R. Lewis,et al. β2 Subunit Contribution to 4/7 α-Conotoxin Binding to the Nicotinic Acetylcholine Receptor* , 2005, Journal of Biological Chemistry.
[51] Wayne Boucher,et al. The CCPN data model for NMR spectroscopy: Development of a software pipeline , 2005, Proteins.
[52] K. Gayler,et al. Drugs from the sea: conopeptides as potential therapeutics. , 2004, Current medicinal chemistry.
[53] A. Gomes,et al. Determinants of Potency on α-Conotoxin MII, a Peptide Antagonist of Neuronal Nicotinic Receptors , 2004 .
[54] David John Adams,et al. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. , 2004, Journal of medicinal chemistry.
[55] D. Craik,et al. Isolation, Structure, and Activity of GID, a Novel α4/7-Conotoxin with an Extended N-terminal Sequence* , 2003, The Journal of Biological Chemistry.
[56] C. Dominguez,et al. HADDOCK: a protein-protein docking approach based on biochemical or biophysical information. , 2003, Journal of the American Chemical Society.
[57] D. Craik,et al. A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in α-Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity* , 2002, The Journal of Biological Chemistry.
[58] Dirk Labudde,et al. A software tool for the prediction of Xaa-Pro peptide bond conformations in proteins based on 13C chemical shift statistics , 2002, Journal of biomolecular NMR.
[59] D. Yoshikami,et al. α-Conotoxin GIC from Conus geographus, a Novel Peptide Antagonist of Nicotinic Acetylcholine Receptors* , 2002, The Journal of Biological Chemistry.
[60] T. Copeland,et al. The P1' specificity of tobacco etch virus protease. , 2002, Biochemical and biophysical research communications.
[61] D. Craik,et al. Two new classes of conopeptides inhibit the α1-adrenoceptor and noradrenaline transporter , 2001, Nature Neuroscience.
[62] D. Yoshikami,et al. Isolation and Characterization of a Novel ConusPeptide with Apparent Antinociceptive Activity* , 2000, The Journal of Biological Chemistry.
[63] H. Nagasawa,et al. 2,2′-Bispyridyl disulfide rapidly induces intramolecular disulfide bonds in peptides , 1999, Peptides.
[64] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[65] D. Craik,et al. Structure determination of the three disulfide bond isomers of alpha-conotoxin GI: a model for the role of disulfide bonds in structural stability. , 1998, Journal of molecular biology.
[66] K. Wüthrich,et al. Torsion angle dynamics for NMR structure calculation with the new program DYANA. , 1997, Journal of molecular biology.
[67] D. Yoshikami,et al. A New -Conotoxin Which Targets 32 Nicotinic Acetylcholine Receptors (*) , 1996, The Journal of Biological Chemistry.
[68] M. Billeter,et al. MOLMOL: a program for display and analysis of macromolecular structures. , 1996, Journal of molecular graphics.
[69] R. Hodges,et al. 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects , 1995, Journal of biomolecular NMR.
[70] A. J. Shaka,et al. Water Suppression That Works. Excitation Sculpting Using Arbitrary Wave-Forms and Pulsed-Field Gradients , 1995 .
[71] T. Blundell,et al. Comparative protein modelling by satisfaction of spatial restraints. , 1993, Journal of molecular biology.
[72] F. Richards,et al. Relationship between nuclear magnetic resonance chemical shift and protein secondary structure. , 1991, Journal of molecular biology.
[73] P. Wright,et al. Sensitivity improvement in proton-detected two-dimensional heteronuclear correlation NMR spectroscopy , 1991 .
[74] K. Wüthrich. NMR of proteins and nucleic acids , 1988 .
[75] Richard R. Ernst,et al. Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy , 1983 .
[76] Richard R. Ernst,et al. Investigation of exchange processes by two‐dimensional NMR spectroscopy , 1979 .
[77] E. G. Sherry,et al. STRUCTURE DETERMINATION I , 1960 .
[78] T. Sixma,et al. AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity , 2007, The EMBO Journal.
[79] Christopher J. Williams,et al. MolProbity: More and better reference data for improved all‐atom structure validation , 2018, Protein science : a publication of the Protein Society.
[80] D. Craik,et al. Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB , 2018 .
[81] Jack Snoeyink,et al. Scientific benchmarks for guiding macromolecular energy function improvement. , 2013, Methods in enzymology.
[82] S. Wonnacott,et al. Nicotinic ACh Receptors , 2007 .
[83] M. Nilges,et al. Influence of non-bonded parameters on the quality of NMR structures: A new force field for NMR structure calculation , 1999, Journal of biomolecular NMR.
[84] F. Barrantes. The Nicotinic Acetylcholine Receptor , 1998, Biotechnology Intelligence Unit.
[85] O. Pongs,et al. A vector for the synthesis of cRNAs encoding Myc epitope-tagged proteins in Xenopus laevis oocytes. , 1995, Gene.
[86] B D Sykes,et al. 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects , 1995, Journal of biomolecular NMR.
[87] A Karlin,et al. Nicotinic acetylcholine receptors. , 1977 .
[88] Miron Livny,et al. RECOORD: A recalculated coordinate database of 500+ proteins from the PDB using restraints from the BioMagResBank , 2005, Proteins.