Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels

1 Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, 2 Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel, 3 Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA, USA and 4 Disease Systems Biology, Novo Nordisk Foundation for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark 5 Present address: Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain * Corresponding author. Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel. Tel.: þ 34 601046898; Fax: þ 34 912945037; E-mail: milana.frenkel@weizmann.ac.il or mmorgenstern@cnio.es

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