Glistenings in foldable intraocular lenses

Purpose: To evaluate the formation of glistenings in foldable intraocular lenses (IOLs) of various materials after cataract surgery. Setting: University Eye Clinic of Trieste, Trieste, Italy. Methods: In this prospective study, 273 patients were randomized to have implantation of 1 of 7 types of foldable IOLs in the capsular bag after phacoemulsification. The IOLs were the CeeOn® Edge 911A (Pharmacia & Upjohn Co.), ACR6D® (Corneal), AcrySof® (Alcon), SI‐40NB (AMO), Hydroview® H60M (Storz), Sensar® (AMO), and Stabibag® (Ioltech). The presence of glistenings in the IOL optic was assessed by slitlamp evaluation 7, 30, 90, 180, 360, and 720 days after surgery. The glistenings were graded at each control. Results: Glistenings were observed in all IOL groups. The percentage of patients with glistenings ranged from 40.0% to 67.5%, with the percentage increasing up to 90 days after surgery and then becoming stable in most groups. The AcrySof group had a continuous increase over time. The mean grade of glistenings increased up to 180 days after surgery and then became stable in most groups. The AcrySof and 911A groups had a continuous increase over time. Conclusions: Glistening formation was observed in 7 different foldable IOLs. The AcrySof group had a higher percentage and a greater density of glistenings.

[1]  A. Kruger,et al.  Two year results: sharp versus rounded optic edges on silicone lenses , 2000, Journal of cataract and refractive surgery.

[2]  O. Schwenn,et al.  Vacuoles in the AcrysofTM Intraocular Lens as Factor of the Presence of Serum in Aqueous Humor , 2001, Ophthalmic Research.

[3]  K. Nakamae,et al.  Optical and atomic force microscopy of an explanted AcrySof intraocular lens with glistenings , 2000, Journal of cataract and refractive surgery.

[4]  D. Apple,et al.  Surgical prevention of posterior capsule opacification. Part 3: Intraocular lens optic barrier effect as a second line of defense. , 2000, Journal of cataract and refractive surgery.

[5]  R. Olson,et al.  Glistenings in the AcrySof intraocular lens: pilot study , 2001, Journal of cataract and refractive surgery.

[6]  Yasuhiko Shiokawa,et al.  Influence of glistenings on the optical quality of acrylic foldable intraocular lens , 2001, The British journal of ophthalmology.

[7]  M. Araie,et al.  Current trends in cataract and refractive surgery in Japan: 1996 survey. , 1998, Japanese journal of ophthalmology.

[8]  O. Nishi,et al.  Effect of round‐edged acrylic intraocular lenses on preventing posterior capsule opacification , 2001, Journal of cataract and refractive surgery.

[9]  Randall J. Olson,et al.  Visual significance of glistenings seen in the AcrySof intraocular lens , 1996, Journal of cataract and refractive surgery.

[10]  N. Ballin Glistenings in injection-molded lens. , 1984, Journal - American Intra-Ocular Implant Society.

[11]  D. Leaming Practice styles and preferences of ASCRS members—1995 survey , 1996, Journal of cataract and refractive surgery.

[12]  D. Sanders,et al.  Foldable Intraocular Lenses , 1993 .

[13]  K. Wickström,et al.  Preventing lens epithelial cell migration using intraocular lenses with sharp rectangular edges , 2000, Journal of cataract and refractive surgery.

[14]  N. Mamalis,et al.  In vitro analysis of AcrySof intraocular lens glistenings in AcryPak and Wagon Wheel packaging , 1998, Journal of cataract and refractive surgery.

[15]  D. Apple,et al.  Surgical prevention of posterior capsule opacification. Part 1: Progress in eliminating this complication of cataract surgery. , 2000, Journal of cataract and refractive surgery.

[16]  T. Kohnen,et al.  Intraindividueller Vergleich von Intraokularlinsen aus hochrefraktivem Silikon (Allergan SI40NB) und hydrophobem Acrylat (Alcon Acrysof MA60BM) 1-Jahresergebnisse , 2000, Der Ophthalmologe.

[17]  O. Nishi,et al.  Inhibition of migrating lens epithelial cells at the capsular bend created by the rectangular optic edge of a posterior chamber intraocular lens. , 1998, Ophthalmic surgery and lasers.

[18]  K. Nakamae,et al.  Glistening formation in an AcrySof lens initiated by spinodal decompositionof the polymer network bytemperature change , 2001, Journal of cataract and refractive surgery.

[19]  T. Oshika,et al.  Current trends in cataract and refractive surgery in Japan--1995 survey. , 1996, Japanese journal of ophthalmology.