Advances in Clinical Medical Research and Healthcare Delivery Advances in Clinical Medical Research and Healthcare Delivery

Abstract ABSTRACT Rhabdomyolysis is muscle necrosis and the release of intracellular muscle components into circulation. Approximately 26,000 cases of rhabdomyolysis are reported annually in the United States. The severity varies greatly from asymptomatic individuals to individuals with life-threatening muscle enzyme elevations along with severe electrolyte abnormalities, acute other organ damage, and compartment syndrome. The mortality rates are as high as 59% in critically ill patients. There are multiple causes of rhabdomyolysis that can be classified as traumatic or non-traumatic. The traumatic cases are usually evident at presentation however, in a non-traumatic setting, the presentation may be misleading. In this specific case report, we discuss a case of rhabdomyolysis with shock liver and acute kidney injury in a 23-year-old male that presented with complaints of back pain and blood in his urine following the recreational use of alcohol and diphenhydramine. Given the frequent use and easy accessibility of both alcohol and diphenhydramine (DPH), it is crucial to be aware of the potential risk of rhabdomyolysis as early recognition and treatment can prevent life-threatening complications.