Evaluation of left atrial and posterior mediastinal anatomy by multidetector helical computed tomography imaging: Relevance to ablation

IntroductionIncreasing use of catheter ablation in the left atrium (LA) requires understanding of substrate anatomy, especially with regard to potential damage to adjacent structures.Methods and resultsWe reviewed multidetector helical computed tomography (MDCT) imaging on 42 subjects, 26 imaged before planned LA ablation for atrial fibrillation (AF), and 16 without AF. LA volume and dimensions were larger in patients with AF (p < 0.05) and the spine and aorta (Ao) impressed the LA more frequently in the AF group. The esophagus (Eo) was the predominant feature on the posterior LA wall, contacting it in all patients. The Ao was in contact with the LA body or the left inferior pulmonary vein (PV) in 32 (76%) of 42 cases, and in 10 it ran along an indentation on the posterior aspect of the LA. The coronary sinus was adjacent to LA ablation sites, the azygos vein was rarely adjacent to those sites, and the left bronchus abutted the PV ostium but not the LA. Two patients had findings that directly impacted the ablation procedure: one patient had a dilated fluid filled Eo with esophageal stricture and underwent nasogastric decompression before ablation, and one was discovered to have an anomalous PV and underwent surgical repair.ConclusionsMDCT imaging identifies structures adjacent to the LA, which could be affected by ablation. Posterior LA topography can be influenced by the position of the Ao or by the proximity of the spine. Preprocedural imaging can characterize anatomic structures that could be vulnerable during ablation, and detect unusual pathology that can affect the treatment plan.

[1]  Volkmar Falk,et al.  Curative treatment of atrial fibrillation with intraoperative radiofrequency ablation: short-term and midterm results. , 2002, The Journal of thoracic and cardiovascular surgery.

[2]  David Schwartzman,et al.  Characterization of left atrium and distal pulmonary vein morphology using multidimensional computed tomography. , 2003, Journal of the American College of Cardiology.

[3]  B. Desjardins,et al.  Computed Tomographic Analysis of the Anatomy of the Left Atrium and the Esophagus: Implications for Left Atrial Catheter Ablation , 2004, Circulation.

[4]  A. d'Avila,et al.  Left Atrial–Esophageal Fistula Following Radiofrequency Catheter Ablation of Atrial Fibrillation , 2004, Journal of cardiovascular electrophysiology.

[5]  O. Alfieri,et al.  Atrio-Esophageal Fistula as a Complication of Percutaneous Transcatheter Ablation of Atrial Fibrillation , 2004, Circulation.

[6]  J. Hoerter,et al.  Mitochondrial Uncoupling Protein 1 Expressed in the Heart of Transgenic Mice Protects Against Ischemic-Reperfusion Damage , 2004, Circulation.

[7]  Moussa Mansour,et al.  Role of Imaging Techniques in Preparation for Catheter Ablation of Atrial Fibrillation , 2004, Journal of cardiovascular electrophysiology.

[8]  R. Cury,et al.  Relationship of the esophagus and aorta to the left atrium and pulmonary veins: implications for catheter ablation of atrial fibrillation. , 2005, Heart rhythm.

[9]  E. Prystowsky,et al.  Should atrial fibrillation ablation be considered first-line therapy for some patients? Should ablation be first-line therapy and for whom? the antagonist position. , 2005, Circulation.

[10]  F. Morady,et al.  Movement of the esophagus during left atrial catheter ablation for atrial fibrillation. , 2005, Journal of the American College of Cardiology.

[11]  A. Verma,et al.  Should atrial fibrillation ablation be considered first-line therapy for some patients? Why atrial fibrillation ablation should be considered first-line therapy for some patients. , 2005, Circulation.

[12]  G. Hindricks,et al.  Topographic Variability of the Esophageal Left Atrial Relation Influencing Ablation Lines in Patients with Atrial Fibrillation , 2005, Journal of cardiovascular electrophysiology.

[13]  Cheng-Yen Chang,et al.  Anatomic relationship of the esophagus and left atrium: implication for catheter ablation of atrial fibrillation. , 2005, Chest.

[14]  Esophageal migration during left atrial catheter ablation for atrial fibrillation , 2005 .

[15]  AB29-1: Atriobronchial fistula formation as a devastating complication of left atrial catheter ablation for atrial fibrillation , 2006 .