Bioprocess development workflow: Transferable physiological knowledge instead of technological correlations
暂无分享,去创建一个
Christoph Herwig | Patrick Sagmeister | Florian Haas | F. Haas | C. Herwig | P. Sagmeister | Wieland N Reichelt
[1] M. Reuss,et al. High-cell-density fermentation for production of L-N-carbamoylase using an expression system based on the Escherichia coli rhaBAD promoter. , 2001, Biotechnology and bioengineering.
[2] Oliver Spadiut,et al. A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris , 2011, Microbial cell factories.
[3] U. Rinas,et al. Simple fed-batch technique for high cell density cultivation of Escherichia coli. , 1995, Journal of biotechnology.
[4] S. Lee,et al. High cell-density culture of Escherichia coli. , 1996, Trends in biotechnology.
[5] M. Uhlén,et al. Upstream strategies to minimize proteolytic degradation upon recombinant production in Escherichia coli. , 1996, Protein expression and purification.
[6] Christoph Herwig,et al. Information Processing: Rate-Based Investigation of Cell Physiological Changes along Design Space Development , 2012, PDA Journal of Pharmaceutical Science and Technology.
[7] A. Rathore,et al. Quality by design for biopharmaceuticals , 2009, Nature Biotechnology.
[8] Christoph Herwig,et al. Model-Based Analysis on the Extractability of Information from Data in Dynamic Fed-Batch Experiments , 2013, Biotechnology progress.
[9] M. Amicosante,et al. Optimizing Escherichia coli as a protein expression platform to produce Mycobacterium tuberculosis immunogenic proteins , 2013, Microbial Cell Factories.
[10] David Pollard,et al. A review of advanced small‐scale parallel bioreactor technology for accelerated process development: Current state and future need , 2011, Biotechnology progress.
[11] L. Shang,et al. Characteristics of fed-batch cultures of recombinant Escherichia coli containing human-like collagen cDNA at different specific growth rates , 2005, Biotechnology Letters.
[12] C. Herwig,et al. Efficient feeding profile optimization for recombinant protein production using physiological information , 2012, Bioprocess and Biosystems Engineering.
[13] K. Terpe. Overview of bacterial expression systems for heterologous protein production: from molecular and biochemical fundamentals to commercial systems , 2006, Applied Microbiology and Biotechnology.
[14] S. Enfors. Control of in vivo proteolysis in the production of recombinant proteins. , 1992, Trends in biotechnology.
[15] C. Curless,et al. Effect of Preinduction Specific Growth Rate on Recombinant Alpha Consensus Interferon Synthesis in Escherichia coli , 1990, Biotechnology progress.
[16] A. Norsyahida,et al. Effects of feeding and induction strategy on the production of BmR1 antigen in recombinant E. coli , 2009, Letters in applied microbiology.
[17] Christoph Herwig,et al. Soft-sensor assisted dynamic investigation of mixed feed bioprocesses , 2013 .
[18] Jonathan I. Betts,et al. Miniature bioreactors: current practices and future opportunities , 2006, Microbial cell factories.
[19] W. Deckwer,et al. High cell density cultivation of Escherichia coli at controlled specific growth rate. , 1991, Journal of biotechnology.
[20] Oliver Spadiut,et al. A dynamic fed batch strategy for a Pichia pastoris mixed feed system to increase process understanding , 2012, Biotechnology progress.
[21] Peter Neubauer,et al. Limiting factors in Escherichia coli fed-batch production of recombinant proteins. , 2003, Biotechnology and bioengineering.
[22] Andre Raw,et al. Quality by Design: Concepts for ANDAs , 2008, The AAPS Journal.
[23] C. Shin,et al. High-level production of recombinant human IFN-α2a with co-expression of tRNAArg(AGG/AGA) in high-cell-density cultures ofEscherichia coli , 2001 .
[24] Tore Hägglund,et al. Feed rate control in fed‐batch fermentations based on frequency content analysis , 2013, Biotechnology progress.
[25] Rimvydas Simutis,et al. Generic model control of the specific growth rate in recombinant Escherichia coli cultivations. , 2006, Journal of biotechnology.
[26] Carl-Fredrik Mandenius,et al. Bioprocess optimization using design‐of‐experiments methodology , 2008, Biotechnology progress.
[27] C. Shin,et al. Enhanced Production of Human Mini‐Proinsulin in Fed‐Batch Cultures at High Cell Density of Escherichia coli BL21(DE3) [pET‐3aT2M2] , 1997, Biotechnology progress.