Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR.

[1]  S. Nordling,et al.  Prognostic significance of cyclin A in gastric cancer , 2006, International journal of cancer.

[2]  W. Weichert,et al.  Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2 , 2006, Modern Pathology.

[3]  Tala Bakheet,et al.  ARED 3.0: the large and diverse AU-rich transcriptome , 2005, Nucleic Acids Res..

[4]  D. Mukhopadhyay,et al.  Role of elongin-binding domain of von hippel lindau gene product on HuR-mediated VPF/VEGF mRNA stability in renal cell carcinoma , 2005, Oncogene.

[5]  C. Haglund,et al.  Cytoplasmic HuR expression correlates with epithelial cancer cell but not with stromal cell cyclooxygenase-2 expression in mucinous ovarian carcinoma. , 2005, Gynecologic oncology.

[6]  M. Gorospe,et al.  Antiapoptotic function of RNA‐binding protein HuR effected through prothymosin α , 2005, The EMBO journal.

[7]  C. Dominguez,et al.  The RNA recognition motif, a plastic RNA‐binding platform to regulate post‐transcriptional gene expression , 2005, The FEBS journal.

[8]  H. Joensuu,et al.  Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma. , 2005, Cancer research.

[9]  M. Gorospe,et al.  HuR: Post-Transcriptional Paths to Malignancy , 2005, RNA biology.

[10]  Jörg Hackermüller,et al.  mRNA Openers and Closers: Modulating AU‐Rich Element‐Controlled mRNA Stability by a Molecular Switch in mRNA Secondary Structure , 2004, Chembiochem : a European journal of chemical biology.

[11]  A. Zou,et al.  Androgens regulate the binding of endogenous HuR to the AU-rich 3'UTRs of HIF-1alpha and EGF mRNA. , 2004, Biochemical and biophysical research communications.

[12]  W. Weichert,et al.  Expression of the ELAV-Like Protein HuR Is Associated with Higher Tumor Grade and Increased Cyclooxygenase-2 Expression in Human Breast Carcinoma , 2004, Clinical Cancer Research.

[13]  W. Weichert,et al.  Overexpression of the Embryonic-Lethal Abnormal Vision-like Protein HuR in Ovarian Carcinoma Is a Prognostic Factor and Is Associated with Increased Cyclooxygenase 2 Expression , 2004, Cancer Research.

[14]  F. Hamada,et al.  ATP Potentiates Interleukin-1β-induced MMP-9 Expression in Mesangial Cells via Recruitment of the ELAV Protein HuR* , 2003, Journal of Biological Chemistry.

[15]  C. Haglund,et al.  Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma. , 2003, Cancer research.

[16]  Myriam Gorospe,et al.  Role of the RNA-binding protein HuR in colon carcinogenesis , 2003, Oncogene.

[17]  Y. Nagamine,et al.  Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 , 2003, Molecular and Cellular Biology.

[18]  G. Giannini,et al.  Chrysanthones, a new source of fungal metabolites with potential antitumor and antiangiogenesis properties. , 2003, Fitoterapia.

[19]  E. Sakashita,et al.  Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins. , 2002, Nucleic acids research.

[20]  R. Voltz.  Paraneoplastic neurological syndromes: an update on diagnosis, pathogenesis, and therapy , 2002, The Lancet Neurology.

[21]  A. Levy,et al.  A 40-bp RNA Element That Mediates Stabilization of Vascular Endothelial Growth Factor mRNA by HuR* , 2002, The Journal of Biological Chemistry.

[22]  J. Steitz,et al.  Delineation of mRNA Export Pathways by the Use of Cell-Permeable Peptides , 2001, Science.

[23]  K. Mahtani,et al.  The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR , 2001, Molecular and Cellular Biology.

[24]  Myriam Gorospe,et al.  HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation , 2000, The EMBO journal.

[25]  J. Jungmann,et al.  Two-dimensional fluorescence intensity distribution analysis: theory and applications. , 2000, Biophysical journal.

[26]  Myriam Gorospe,et al.  HuR Regulates p21 mRNA Stabilization by UV Light , 2000, Molecular and Cellular Biology.

[27]  S. Schwartz,et al.  Inhibitory activity of the human papillomavirus type 1 AU-rich element correlates inversely with the levels of the elav-like HuR protein in the cell cytoplasm , 2000, Archives of Virology.

[28]  D. Ullmann,et al.  Fluorescence-intensity distribution analysis and its application in biomolecular detection technology. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Thomas D. Y. Chung,et al.  A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays , 1999, Journal of biomolecular screening.

[30]  K. Tatsuta,et al.  Total synthesis of MS-444, a myosin light chain kinase inhibitor. , 1997, The Journal of antibiotics.

[31]  I. Kawamoto,et al.  MS-444, a new inhibitor of myosin light chain kinase from Micromonospora sp. KY7123. , 1995, The Journal of antibiotics.

[32]  M. Rosenfeld,et al.  Paraneoplastic Encephalomyelitis Antigens Bind to the AU-rich Elements of mRNA , 1995, Neurology.

[33]  C. Khosla,et al.  Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[34]  Qingwei Zhang,et al.  Synthesis of (.+-.)-okicenone and (.+-.)-aloesaponol III , 1993 .

[35]  C. Cordon-Cardo,et al.  The expression of the Hu (paraneoplastic encephalomyelitis/sensory neuronopathy) antigen in human normal and tumor tissues. , 1992, The American journal of pathology.

[36]  M. Rosenblum,et al.  Detection of the anti‐Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuronopathy , 1991, Neurology.

[37]  C. Y. Huang.  Determination of binding stoichiometry by the continuous variation method: the Job plot. , 1982, Methods in enzymology.

[38]  J. Żeromski,et al.  Immunofluorescent detection of antibodies against neurones in sensory carcinomatous neuropathy. , 1965, Brain : a journal of neurology.