UniProt: the Universal Protein knowledgebase

To provide the scientific community with a single, centralized, authoritative resource for protein sequences and functional information, the Swiss-Prot, TrEMBL and PIR protein database activities have united to form the Universal Protein Knowledgebase (UniProt) consortium. Our mission is to provide a comprehensive, fully classified, richly and accurately annotated protein sequence knowledgebase, with extensive cross-references and query interfaces. The central database will have two sections, corresponding to the familiar Swiss-Prot (fully manually curated entries) and TrEMBL (enriched with automated classification, annotation and extensive cross-references). For convenient sequence searches, UniProt also provides several non-redundant sequence databases. The UniProt NREF (UniRef) databases provide representative subsets of the knowledgebase suitable for efficient searching. The comprehensive UniProt Archive (UniParc) is updated daily from many public source databases. The UniProt databases can be accessed online (http://www.uniprot.org) or downloaded in several formats (ftp://ftp.uniprot.org/pub). The scientific community is encouraged to submit data for inclusion in UniProt.

Cathy H. Wu | Jerven T. Bolleman | Béatrice A. Cuche | C. R. Vinayaka | Alan W. Sousa da Silva | W. C. Barker | Leyla Jael García Castro | C. Arighi | D. Natale | A. Bateman | A. Bairoch | I. Xenarios | J. Garavelli | G. Georghiou | M. Magrane | R. Apweiler | T. Sawford | M. Martin | C. O’Donovan | B. Roechert | S. Poux | B. Boeckmann | R. Lopez | C. Sigrist | A. Bridge | L. Bougueleret | Weizhong Li | L. Breuza | M. Feuermann | U. Hinz | P. Masson | I. Pedruzzi | Serenella Ferro | E. Gasteiger | Hongzhan Huang | N. Redaschi | L. Yeh | A. Auchincloss | K. Axelsen | B. Bely | M. Blatter | E. Boutet | R. Britto | H. Bye-A-Jee | E. Coudert | A. Estreicher | L. Famiglietti | P. Garmiri | A. Gos | N. Gruaz-Gumowski | E. Hatton-Ellis | C. Hulo | F. Jungo | G. Keller | K. Laiho | D. Lieberherr | Y. Lussi | K. Pichler | C. Rivoire | E. Speretta | A. Shypitsyna | A. Stutz | S. Sundaram | M. Tognolli | N. Tyagi | K. Warner | R. Zaru | Ghislaine Argoud-Puy | P. McGarvey | H. Zellner | S. Paesano | E. Alpi | E. de Castro | B. Bursteinas | Michel Schneider | A. Renaux | Qinghua Wang | A. Morgat | Séverine Duvaud | A. Veuthey | V. Volynkin | M. Bingley | Manuela Pruess | Parit Bansal | K. Ross | Chuming Chen | Rabie Saidi | T. Lombardot | L. Aimo | Monica Pozzato | S. Rosanoff | Tunca Doğan | R. Antunes | T. Neto | S. Gehant | Jian Zhang | Andrew Nightingale | Jie Luo | P. Lemercier | L. Arminski | Yuqi Wang | Yongxing Chen | A. Cowley | B. Palka | Delphine Baratin | D. Poggioli | M. Doche | D. Dornevil | X. Martin | S. Pilbout | K. Sonesson | S. Staehli | L. Verbregue | Alex Maria Jesus Claire Michele Emanuele Ricardo Benoit Bateman Martin O’Donovan Magrane Alpi Antune | C. Bonilla | M. D. Giorgi | F. Fazzini | L. Figueira | Daniel Gonzalez | Wudong Liu | Alistair MacDougall | S. Pundir | L. Pureza | G. Qi | Edward Turner | T. Wardell | X. Watkins | C. Casal-Casas | V. Gerritsen | V. Lara | N. Nouspikel

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