In vitro modelling of Alzheimer's disease: Degeneration and cell death induced by viral delivery of amyloid and tau
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[1] B. Platt,et al. Culturing conditions determine neuronal and glial excitability , 2010, Journal of Neuroscience Methods.
[2] J. Geiger,et al. Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet. , 2010, Free radical biology & medicine.
[3] D. Selkoe,et al. The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia. , 2010, Brain : a journal of neurology.
[4] K. Blennow,et al. PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses. , 2010, Journal of Alzheimer's disease : JAD.
[5] D. Simon,et al. Two pyridine derivatives as potential Cu(II) and Zn(II) chelators in therapy for Alzheimer's disease. , 2010, Dalton transactions.
[6] M. Oz,et al. Methylene blue and Alzheimer's disease. , 2009, Biochemical pharmacology.
[7] Andrew J. Murray,et al. cGMP promotes neurite outgrowth and growth cone turning and improves axon regeneration on spinal cord tissue in combination with cAMP , 2009, Brain Research.
[8] Long-chuan Yu,et al. Intracellular amyloid induces impairments on electrophysiological properties of cultured human neurons , 2009, Neuroscience Letters.
[9] H. Möller,et al. Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study. , 2009, The Journal of clinical psychiatry.
[10] P. Dolan,et al. Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons , 2009, The Journal of Biological Chemistry.
[11] C. Sindic,et al. Expression of Human Amyloid Precursor Protein in Rat Cortical Neurons Inhibits Calcium Oscillations , 2009, The Journal of Neuroscience.
[12] B. Platt,et al. Cannabidiol Targets Mitochondria to Regulate Intracellular Ca2+ Levels , 2009, The Journal of Neuroscience.
[13] D. Bennett,et al. Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease. , 2008, The American journal of pathology.
[14] K. Tomoo,et al. Different inhibitory response of cyanidin and methylene blue for filament formation of tau microtubule-binding domain. , 2008, Biochemical and biophysical research communications.
[15] K. Blennow,et al. Safety, efficacy, and biomarker findings of PBT2 in targeting Aβ as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial , 2008, The Lancet Neurology.
[16] S. Cullheim,et al. Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro , 2008, Molecular and Cellular Neuroscience.
[17] Andrew J. Murray,et al. Epac mediates cyclic AMP-dependent axon growth, guidance and regeneration , 2008, Molecular and Cellular Neuroscience.
[18] B. Winblad,et al. APPswe mutation increases the frequency of spontaneous Ca2+-oscillations in rat hippocampal neurons , 2008, Neuroscience Letters.
[19] Kathleen A. Boyle,et al. Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[20] Till G. A. Mack,et al. Tau kinase inhibitors protect hippocampal synapses despite of insoluble tau accumulation , 2008, Molecular and Cellular Neuroscience.
[21] R. Cappai,et al. Copper binding to the Alzheimer’s disease amyloid precursor protein , 2007, European Biophysics Journal.
[22] Grace E. Stutzmann. The Pathogenesis of Alzheimers Disease—Is It a Lifelong “Calciumopathy”? , 2007, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[23] B. Platt,et al. Modulation of hippocampal calcium signalling and plasticity by serine/threonine protein phosphatases , 2007, Journal of neurochemistry.
[24] L. Breydo,et al. Methylene blue inhibits amyloid Abeta oligomerization by promoting fibrillization. , 2007, Biochemistry.
[25] F. LaFerla,et al. Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles. , 2007, The American journal of pathology.
[26] S. Ferreira,et al. Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts , 2007, Progress in Neurobiology.
[27] Bernardo L Sabatini,et al. Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway , 2007, The Journal of Neuroscience.
[28] K. Davies,et al. Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress. , 2006, The Biochemical journal.
[29] T. Iwatsubo,et al. The intracellular domain of the amyloid precursor protein (AICD) enhances the p53-mediated apoptosis. , 2006, Biochemical and biophysical research communications.
[30] L. Zacharia,et al. Caffeine protects Alzheimer’s mice against cognitive impairment and reduces brain β-amyloid production , 2006, Neuroscience.
[31] E. Mandelkow,et al. Inhibition of APP Trafficking by Tau Protein Does Not Increase the Generation of Amyloid‐β Peptides , 2006, Traffic.
[32] Y. Suh,et al. Phosphorylation of Amyloid Precursor Protein (APP) at Thr668 Regulates the Nuclear Translocation of the APP Intracellular Domain and Induces Neurodegeneration , 2006, Molecular and Cellular Biology.
[33] J. Vickers,et al. No difference in expression of apoptosis-related proteins and apoptotic morphology in control, pathologically aged and Alzheimer's disease cases , 2006, Neurobiology of Disease.
[34] M. Gallagher,et al. A specific amyloid-β protein assembly in the brain impairs memory , 2006, Nature.
[35] M. Goedert. Tau gene mutations and their effects , 2005, Movement disorders : official journal of the Movement Disorder Society.
[36] G. Riedel,et al. Altered Cellular Distribution of Phospho‐Tau Proteins Coincides with Impaired Retrograde Axonal Transport in Neurons of Aged Rats , 2005, Annals of the New York Academy of Sciences.
[37] Takeshi Iwatsubo,et al. Inhibition of Heparin-induced Tau Filament Formation by Phenothiazines, Polyphenols, and Porphyrins* , 2005, Journal of Biological Chemistry.
[38] C. Haass,et al. Amyloid β-induced Changes in Nitric Oxide Production and Mitochondrial Activity Lead to Apoptosis* , 2004, Journal of Biological Chemistry.
[39] Dominic M. Walsh,et al. Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease , 2004, Neuron.
[40] F. Gonzalez-Lima,et al. Methylene blue improves brain oxidative metabolism and memory retention in rats , 2004, Pharmacology Biochemistry and Behavior.
[41] F. Liu,et al. Divergent roles of GSK3 and CDK5 in APP processing. , 2003, Biochemical and biophysical research communications.
[42] L. Tsai,et al. APP processing is regulated by cytoplasmic phosphorylation , 2003, The Journal of cell biology.
[43] R. Jope. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. , 2003, Trends in pharmacological sciences.
[44] B. Strooper,et al. In Vitro Studies of Flemish, Dutch, and Wild-Type β-Amyloid Provide Evidence for Two-Staged Neurotoxicity , 2002, Neurobiology of Disease.
[45] G. Lynch,et al. Uptake and pathogenic effects of amyloid beta peptide 1–42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists , 2002, Neuroscience.
[46] J. Octave,et al. Intracellular Amyloid-β1–42, but Not Extracellular Soluble Amyloid-β Peptides, Induces Neuronal Apoptosis* , 2002, The Journal of Biological Chemistry.
[47] W. K. Cullen,et al. Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo , 2002, Nature.
[48] E. Mandelkow,et al. Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress , 2002, The Journal of cell biology.
[49] A. LeBlanc,et al. Selective cytotoxicity of intracellular amyloid β peptide1–42 through p53 and Bax in cultured primary human neurons , 2002, The Journal of cell biology.
[50] K. Tominaga-Yoshino,et al. Neurotoxic and neuroprotective effects of glutamate are enhanced by introduction of amyloid precursor protein cDNA , 2001, Brain Research.
[51] D. Selkoe. Alzheimer's disease: genes, proteins, and therapy. , 2001, Physiological reviews.
[52] R. Hata,et al. Caspase-3 activation and inflammatory responses in rat hippocampus inoculated with a recombinant adenovirus expressing the Alzheimer amyloid precursor protein. , 2000, Brain research. Molecular brain research.
[53] P. Greengard,et al. Neuron‐Specific Phosphorylation of Alzheimer's β‐Amyloid Precursor Protein by Cyclin‐Dependent Kinase 5 , 2000, Journal of neurochemistry.
[54] K. Jellinger,et al. Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death. , 1999, The American journal of pathology.
[55] I. Lieberburg,et al. Cellular mechanisms of beta-amyloid production and secretion. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[56] E. Koo,et al. Recombinant adenovirus is an appropriate vector for endocytotic protein trafficking studies in cultured neurons , 1999, Journal of Neuroscience Methods.
[57] D K Ingram,et al. Death of PC12 cells and hippocampal neurons induced by adenoviral‐mediated FAD human amyloid precursor protein gene expression , 1999, Journal of neuroscience research.
[58] E. Mandelkow,et al. Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease , 1998, The Journal of cell biology.
[59] R. Essalmani,et al. The Long Term Adenoviral Expression of the Human Amyloid Precursor Protein Shows Different Secretase Activities in Rat Cortical Neurons and Astrocytes* , 1998, The Journal of Biological Chemistry.
[60] H. Okamura,et al. Degeneration In Vivo of Rat Hippocampal Neurons by Wild-Type Alzheimer Amyloid Precursor Protein Overexpressed by Adenovirus-Mediated Gene Transfer , 1998, The Journal of Neuroscience.
[61] A. Ogura,et al. Glutamate responsiveness enhanced in neurones expressing amyloid precursor protein , 1997, Neuroreport.
[62] M. Roth,et al. Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[63] B. Winblad,et al. Excessive production of amyloid beta-protein by peripheral cells of symptomatic and presymptomatic patients carrying the Swedish familial Alzheimer disease mutation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[64] Lawrence C. Katz,et al. Neuronal transfection in brain slices using particle-mediated gene transfer , 1994, Neuron.
[65] S. Squazzo,et al. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. , 1994, The Journal of biological chemistry.
[66] Jian-Zhi Wang,et al. Tau overexpression inhibits cell apoptosis with the mechanisms involving multiple viability-related factors. , 2010, Journal of Alzheimer's disease : JAD.
[67] L. Buée,et al. Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology. , 2010, Journal of Alzheimer's disease : JAD.
[68] Q. Tian,et al. Overexpression of tau proteins antagonizes amyloid-beta-potentiated apoptosis through mitochondria-caspase-3 pathway in N2a cells. , 2010, Journal of Alzheimer's disease : JAD.
[69] H. Basun,et al. Increase of BDNF serum concentration in lithium treated patients with early Alzheimer's disease. , 2009, Journal of Alzheimer's disease : JAD.
[70] V. Echeverria,et al. Caffeine reverses cognitive impairment and decreases brain amyloid-beta levels in aged Alzheimer's disease mice. , 2009, Journal of Alzheimer's disease : JAD.
[71] D. Selkoe,et al. Natural oligomers of the amyloid-β protein specifically disrupt cognitive function , 2005, Nature Neuroscience.
[72] L. Peris,et al. Tau Protein Function in Axonal Formation , 2004, Neurochemical Research.
[73] Xiongwei Zhu,et al. Abortive apoptosis in Alzheimer's disease , 2001, Acta Neuropathologica.