Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis
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[1] G. P. Beardsley,et al. Human 5-Aminoimidazole-4-carboxamide Ribonucleotide Transformylase/Inosine 5′-Monophosphate Cyclohydrolase , 2001, The Journal of Biological Chemistry.
[2] S. Benkovic,et al. Human AICAR transformylase: role of the 4-carboxamide of AICAR in binding and catalysis. , 2000, Biochemistry.
[3] I. Wilson,et al. Crystallization and preliminary crystallographic investigations of avian 5-aminoimidazole-4-carboxamide ribonucleotide transformylase-inosine monophosphate cyclohydrolase expressed in Escherichia coli. , 2000, Acta crystallographica. Section D, Biological crystallography.
[4] D. Appling,et al. Characterization of Two 5-Aminoimidazole-4-carboxamide Ribonucleotide Transformylase/Inosine Monophosphate Cyclohydrolase Isozymes from Saccharomyces cerevisiae * , 2000, The Journal of Biological Chemistry.
[5] T. Yeates,et al. The structure of adenylosuccinate lyase, an enzyme with dual activity in the de novo purine biosynthetic pathway. , 2000, Structure.
[6] S E Ealick,et al. Crystal structure of Escherichia coli PurE, an unusual mutase in the purine biosynthetic pathway. , 1999, Structure.
[7] R. Stroud,et al. The structural mechanism for half-the-sites reactivity in an enzyme, thymidylate synthase, involves a relay of changes between subunits. , 1999, Biochemistry.
[8] J. Stubbe,et al. X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution. , 1999, Structure.
[9] S. Benkovic,et al. A multisubstrate adduct inhibitor of AICAR transformylase. , 1999, Journal of medicinal chemistry.
[10] S. B. Gates,et al. Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis. , 1999, Seminars in oncology.
[11] D. Harrison,et al. The crystal structure of methylglyoxal synthase from Escherichia coli. , 1999, Structure.
[12] A. Jabs,et al. Non-proline cis peptide bonds in proteins. , 1999, Journal of molecular biology.
[13] J. Stubbe,et al. X-ray crystal structure of glycinamide ribonucleotide synthetase from Escherichia coli. , 1998, Biochemistry.
[14] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[15] A. Jabs,et al. Peptide bonds revisited , 1998, Nature Structural &Molecular Biology.
[16] K. Wilson,et al. The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis. , 1998, Structure.
[17] K. Anderson,et al. Structure and functional relationships in human pur H. , 1998, Advances in experimental medicine and biology.
[18] J. L. Smith,et al. Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site. , 1997, Biochemistry.
[19] Z. Otwinowski,et al. [20] Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.
[20] E A Merritt,et al. Raster3D: photorealistic molecular graphics. , 1997, Methods in enzymology.
[21] G. Bricogne,et al. [27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods. , 1997, Methods in enzymology.
[22] T. Terwilliger,et al. Correlated phasing of multiple isomorphous replacement data. , 1996, Acta crystallographica. Section D, Biological crystallography.
[23] B. Cronstein,et al. The anti-inflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites. , 1996, Journal of immunology.
[24] G. P. Beardsley,et al. The Human purH Gene Product, 5-Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase , 1996, The Journal of Biological Chemistry.
[25] S. Jones,et al. Principles of protein-protein interactions. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[26] J. Abrahams,et al. Methods used in the structure determination of bovine mitochondrial F1 ATPase. , 1996, Acta crystallographica. Section D, Biological crystallography.
[27] C. Sessa,et al. Mechanism of cytotoxicity of 5,10-dideazatetrahydrofolic acid in human ovarian carcinoma cells in vitro and modulation of the drug activity by folic or folinic acid. , 1994, British Journal of Cancer.
[28] M. Lawrence,et al. Shape complementarity at protein/protein interfaces. , 1993, Journal of molecular biology.
[29] B. Cronstein,et al. The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. , 1993, The Journal of clinical investigation.
[30] C. Sander,et al. Protein structure comparison by alignment of distance matrices. , 1993, Journal of molecular biology.
[31] V S Lamzin,et al. Automated refinement of protein models. , 1993, Acta crystallographica. Section D, Biological crystallography.
[32] I. Wilson,et al. Crystal structure of glycinamide ribonucleotide transformylase from Escherichia coli at 3.0 A resolution. A target enzyme for chemotherapy. , 1992, Journal of molecular biology.
[33] S. Morgan,et al. Inhibition of folate-dependent enzymes by non-steroidal anti-inflammatory drugs. , 1992, The Biochemical journal.
[34] G. Schulz. Binding of nucleotides by proteins , 1992, Current Biology.
[35] A. Brunger. Free R value: a novel statistical quantity for assessing the accuracy of crystal structures. , 1992 .
[36] J. Dixon,et al. De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase. , 1991, Gene.
[37] P. Kraulis. A program to produce both detailed and schematic plots of protein structures , 1991 .
[38] J. Zou,et al. Improved methods for building protein models in electron density maps and the location of errors in these models. , 1991, Acta crystallographica. Section A, Foundations of crystallography.
[39] R. Moran,et al. A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis. , 1989, The Journal of biological chemistry.
[40] C. Allegra,et al. Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[41] M. L. Connolly. Solvent-accessible surfaces of proteins and nucleic acids. , 1983, Science.
[42] S. Benkovic,et al. On the purification and mechanism of action of 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase from chicken liver. , 1981, Biochemistry.
[43] B. Matthews. Solvent content of protein crystals. , 1968, Journal of molecular biology.