Extended report: Life course body mass index and risk of knee osteoarthritis at the age of 53 years: evidence from the 1946 British birth cohort study

Introduction The authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA.

[1]  D. Felson Identifying different osteoarthritis phenotypes through epidemiology. , 2010, Osteoarthritis and cartilage.

[2]  S Kirschner,et al.  EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis , 2009, Annals of the rheumatic diseases.

[3]  R. Collins,et al.  Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies , 2009, The Lancet.

[4]  Rebecca Hardy,et al.  A structured approach to modelling the effects of binary exposure variables over the life course , 2008, International journal of epidemiology.

[5]  M. Grotle,et al.  Obesity and osteoarthritis in knee, hip and/or hand: An epidemiological study in the general population with 10 years follow-up , 2008, BMC musculoskeletal disorders.

[6]  P. Nilsson,et al.  Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study , 2008, Annals of the rheumatic diseases.

[7]  A. Tukker,et al.  Overweight and health problems of the lower extremities: osteoarthritis, pain and disability , 2008, Public Health Nutrition.

[8]  L. Sharma,et al.  Overweight: advancing our understanding of its impact on the knee and the hip , 2006, Annals of the rheumatic diseases.

[9]  S. Bierma-Zeinstra,et al.  Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: The Rotterdam Study , 2006, Annals of the rheumatic diseases.

[10]  June Stevens,et al.  Anthropometric Measures, Body Composition, Body Fat Distribution, and Knee Osteoarthritis in Women , 2006, Obesity.

[11]  A. Thelin,et al.  Knee osteoarthritis and body mass index: a population‐based case–control study , 2005, Scandinavian journal of rheumatology.

[12]  R. Hardy,et al.  Grip strength, postural control, and functional leg power in a representative cohort of British men and women: associations with physical activity, health status, and socioeconomic conditions. , 2005, The journals of gerontology. Series A, Biological sciences and medical sciences.

[13]  David T Felson,et al.  The effect of body weight on progression of knee osteoarthritis is dependent on alignment. , 2004, Arthritis and rheumatism.

[14]  Peter Croft,et al.  The prevalence and history of knee osteoarthritis in general practice: a case-control study. , 2004, Family practice.

[15]  H. Riihimäki,et al.  Weight changes and the risk of knee osteoarthritis requiring arthroplasty , 2004, Annals of the rheumatic diseases.

[16]  R. Fitzpatrick,et al.  An investigation of risk factors for symptomatic osteoarthritis of the knee in women using a life course approach , 2003, Journal of epidemiology and community health.

[17]  Y. Ben-Shlomo,et al.  A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives. , 2002, International journal of epidemiology.

[18]  L. Sharma,et al.  The role of knee alignment in disease progression and functional decline in knee osteoarthritis. , 2001, JAMA.

[19]  R. McCarney,et al.  Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care , 2001, Annals of the rheumatic diseases.

[20]  C. Cooper,et al.  Risk factors for the incidence and progression of radiographic knee osteoarthritis. , 2000, Arthritis and rheumatism.

[21]  M. Hochberg,et al.  Body mass index in young men and the risk of subsequent knee and hip osteoarthritis. , 1999, The American journal of medicine.

[22]  C. Hogstedt,et al.  Osteoarthrosis of the knee in men and women in association with overweight, smoking, and hormone therapy , 1999, Annals of the rheumatic diseases.

[23]  D. Felson,et al.  An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. , 1998, Arthritis and rheumatism.

[24]  Daniel Levy,et al.  Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham Study. , 1997, Arthritis and rheumatism.

[25]  H. Riihimäki,et al.  Overweight, gender and knee osteoarthritis. , 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[26]  T. Spector,et al.  The relationship of obesity, fat distribution and osteoarthritis in women in the general population: the Chingford Study. , 1993, The Journal of rheumatology.

[27]  Richard M. Aspden,et al.  Obesity punches above its weight in osteoarthritis , 2011, Nature Reviews Rheumatology.

[28]  K. Muir,et al.  Lifetime body mass index, other anthropometric measures of obesity and risk of knee or hip osteoarthritis in the GOAL case-control study. , 2011, Osteoarthritis and cartilage.

[29]  M. Blagojevic,et al.  Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. , 2010, Osteoarthritis and cartilage.

[30]  B. Caballero The global epidemic of obesity: an overview. , 2007, Epidemiologic reviews.

[31]  H. Malchau,et al.  Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men , 2005, European Journal of Epidemiology.

[32]  T. Spector,et al.  Incidence and risk factors for radiographic knee osteoarthritis in middle-aged women: the Chingford Study. , 1999, Arthritis and rheumatism.

[33]  T. Cole The LMS method for constructing normalized growth standards. , 1990, European journal of clinical nutrition.