Lipid-induced insulin resistance: unravelling the mechanism
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[1] A. Butte,et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[2] G. Shulman,et al. Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance , 2007, Proceedings of the National Academy of Sciences.
[3] A. Golay,et al. Pathways from obesity to diabetes , 2002, International Journal of Obesity.
[4] G. Shulman,et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. , 2007, The Journal of clinical investigation.
[5] M. Digman,et al. Mechanism of Diacylglycerol-induced Membrane Targeting and Activation of Protein Kinase Cδ* , 2004, Journal of Biological Chemistry.
[6] Hitoshi Shimano,et al. Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance , 2007, Nature Medicine.
[7] S. Crooke. Progress in antisense technology. , 2004, Annual review of medicine.
[8] K. Petersen,et al. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. , 2002, The Journal of clinical investigation.
[9] A. Kotronen,et al. Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome , 2007, Diabetologia.
[10] P. Scifo,et al. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. , 1999, Diabetes.
[11] Y. Nakagawa,et al. Age-Related Changes in Intramyocellular Lipid in Humans by in vivo 1H-MR Spectroscopy , 2007, Gerontology.
[12] L. J. Hardies,et al. Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. , 2004, The Journal of clinical endocrinology and metabolism.
[13] G. Shulman,et al. Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance. , 2007, The Journal of clinical investigation.
[14] K. Petersen,et al. Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content. , 2002, American journal of physiology. Endocrinology and metabolism.
[15] K. Petersen,et al. Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. , 2002, The Journal of clinical investigation.
[16] Dan R. Littman,et al. PKC-θ knockout mice are protected from fat-induced insulin resistance , 2004 .
[17] Simon C Watkins,et al. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. , 2001, The Journal of clinical endocrinology and metabolism.
[18] K. Gumireddy,et al. Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver. , 2005, Diabetes.
[19] H. Lodish,et al. Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle. , 2004, The Journal of clinical investigation.
[20] F. Schick,et al. Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene , 2009, Diabetes.
[21] M. White,et al. Phosphorylation of Ser307 in Insulin Receptor Substrate-1 Blocks Interactions with the Insulin Receptor and Inhibits Insulin Action* , 2002, The Journal of Biological Chemistry.
[22] D L Rothman,et al. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. , 1999, The Journal of clinical investigation.
[23] A. Diehl,et al. Nonalcoholic fatty liver disease as a complication of insulin resistance. , 2007, The Medical clinics of North America.
[24] E. Yilmaz,et al. Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes , 2006, Science.
[25] D. Cooper,et al. Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance , 1998, The Lancet.
[26] C. Kahn,et al. Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity. , 1988, The Journal of biological chemistry.
[27] R. Ahima,et al. Inhibition of ADRP prevents diet-induced insulin resistance. , 2008, American journal of physiology. Gastrointestinal and liver physiology.
[28] Jennifer L. Pomeranz,et al. A crisis in the marketplace: how food marketing contributes to childhood obesity and what can be done. , 2009, Annual review of public health.
[29] E. Kraegen,et al. Alterations in the Expression and Cellular Localization of Protein Kinase C Isozymes ε and θ Are Associated With Insulin Resistance in Skeletal Muscle of the High-Fat–Fed Rat , 1997, Diabetes.
[30] G. Hotamisligil. Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes. , 2005, Diabetes.
[31] A. Prentice,et al. Evolutionary origins of the obesity epidemic: natural selection of thrifty genes or genetic drift following predation release? , 2008, International Journal of Obesity.
[32] G. Shulman,et al. Prevention of fat-induced insulin resistance by salicylate. , 2001, The Journal of clinical investigation.
[33] X. Papademetris,et al. The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome , 2007, Proceedings of the National Academy of Sciences.
[34] L. N. Valenti,et al. Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease. , 2010, The New England journal of medicine.
[35] R. Shulman,et al. Validation of 13c nmr measurement of human skeletal muscle glycogen by direct biochemical assay of needle biopsy samples , 1992, Magnetic resonance in medicine.
[36] Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. , 2002 .
[37] R G Shulman,et al. Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. , 1990, The New England journal of medicine.
[38] R. Andres,et al. Contribution of impaired glucose tolerance in subjects with the metabolic syndrome: Baltimore Longitudinal Study of Aging. , 2005, Metabolism: clinical and experimental.
[39] A. Goldfine,et al. Inflammation and insulin resistance. , 2006, The Journal of clinical investigation.
[40] C. Bogardus,et al. Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. , 2002, Diabetes.
[41] A. Newton,et al. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. , 2003, The Biochemical journal.
[42] E. Kraegen,et al. Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat. , 1997, Diabetes.
[43] Claudio Cobelli,et al. Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men , 2006, Proceedings of the National Academy of Sciences.
[44] Y. Miyazaki,et al. Separate contribution of diabetes, total fat mass, and fat topography to glucose production, gluconeogenesis, and glycogenolysis. , 2004, The Journal of clinical endocrinology and metabolism.
[45] G. Shulman,et al. Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. , 2006, The Journal of clinical investigation.
[46] M. Gillum,et al. Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice. , 2006, Diabetes.
[47] K. Petersen,et al. 26 IMPAIRED MITOCHONDRIAL ACTIVITY IN INSULIN RESISTANT OFFSPRING OF TYPE 2 DIABETICS. , 2004, Journal of Investigative Medicine.
[48] R. Hammer,et al. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy , 1999, Nature.
[49] N. Ruderman,et al. Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α , 2002 .
[50] G. Shulman,et al. Contrasting Effects of IRS-1 Versus IRS-2 Gene Disruption on Carbohydrate and Lipid Metabolism in Vivo * , 2000, The Journal of Biological Chemistry.
[51] J C Stanley,et al. The glucose-fatty acid cycle. Relationship between glucose utilization in muscle, fatty acid oxidation in muscle and lipolysis in adipose tissue. , 1981, British journal of anaesthesia.
[52] S. Dufour,et al. Interethnic Differences in Muscle, Liver and Abdominal Fat Partitioning in Obese Adolescents , 2007, PloS one.
[53] K. Siddle,et al. Phorbol ester-induced downregulation of protein kinase C potentiates insulin receptor tyrosine autophosphorylation: evidence for a major constitutive role in insulin receptor regulation. , 1990, Biochemical Society transactions.
[54] S. Watkins,et al. Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism , 2008, Cell.
[55] D. James,et al. Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. , 2010, Cell metabolism.
[56] J. Horowitz,et al. Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance. , 2007, The Journal of clinical investigation.
[57] K. Petersen,et al. Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. , 2005, Diabetes.
[58] G. Shulman,et al. Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle* , 2002, The Journal of Biological Chemistry.
[59] L. Glimcher,et al. Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes , 2004, Science.
[60] G. Shulman,et al. Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. , 1999, Diabetes.
[61] D. Chinkes,et al. Intramuscular and liver triglycerides are increased in the elderly. , 2004, The Journal of clinical endocrinology and metabolism.
[62] R. Shulman,et al. Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[63] Douglas L. Rothman,et al. Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance , 2003, Science.
[64] C. Kahn,et al. Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus. , 1993, The Journal of clinical investigation.
[65] F. Schick,et al. Fast elevation of the intramyocellular lipid content in the presence of circulating free fatty acids and hyperinsulinemia: A dynamic 1H‐MRS study , 2001, Magnetic resonance in medicine.
[66] K. Flegal,et al. Prevalence of Diabetes, Impaired Fasting Glucose, and Impaired Glucose Tolerance in U.S. Adults: The Third National Health and Nutrition Examination Survey, 1988–1994 , 1998, Diabetes Care.
[67] L. Grummer-Strawn,et al. Trends in state-specific prevalence of overweight and underweight in 2- through 4-year-old children from low-income families from 1989 through 2000. , 2004, Archives of pediatrics & adolescent medicine.
[68] Alexander Pertsemlidis,et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease , 2008, Nature Genetics.
[69] G. Shulman,et al. PKC-theta knockout mice are protected from fat-induced insulin resistance. , 2004, The Journal of clinical investigation.
[70] K. Petersen,et al. Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients , 2007, Diabetes.
[71] G. Boden. Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM , 1997, Diabetes.
[72] C. Kahn,et al. Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. , 1993, The Journal of clinical investigation.
[73] H. Nakano,et al. [Epidemiology of diabetes mellitus in the elderly]. , 2002, Nihon rinsho. Japanese journal of clinical medicine.
[74] K. Lindor,et al. Nonalcoholic fatty liver disease , 2005, Canadian Medical Association Journal.
[75] W. James,et al. A life course approach to diet, nutrition and the prevention of chronic diseases , 2004, Public Health Nutrition.
[76] G. Shulman,et al. Mechanism of Insulin Resistance in A-ZIP/F-1 Fatless Mice* , 2000, The Journal of Biological Chemistry.
[77] F. Schick,et al. Circulating Palmitoleate Strongly and Independently Predicts Insulin Sensitivity in Humans , 2009, Diabetes Care.
[78] A. Garg. Acquired and inherited lipodystrophies. , 2004, The New England journal of medicine.
[79] C. Kahn,et al. Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4. , 2001, The Journal of clinical investigation.
[80] R. Eckel,et al. Skeletal Muscle–Specific Deletion of Lipoprotein Lipase Enhances Insulin Signaling in Skeletal Muscle but Causes Insulin Resistance in Liver and Other Tissues , 2008, Diabetes.
[81] K. Petersen,et al. Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy , 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[82] B. Popkin,et al. Overweight exceeds underweight among women in most developing countries. , 2005, The American journal of clinical nutrition.
[83] N. Ruderman,et al. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. , 2002, Diabetes.
[84] Vincent Lebon,et al. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. , 2002, Diabetes.
[85] B. S. Mohammed,et al. Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss , 2009, Diabetes.
[86] K. Anderson,et al. Epidemiology of diabetes mellitus in the elderly. The Framingham Study. , 1986, The American journal of medicine.
[87] S. Kahn,et al. Review: The role of insulin resistance in nonalcoholic fatty liver disease. , 2006, The Journal of clinical endocrinology and metabolism.
[88] A. McCullough,et al. The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease. , 2004, Clinics in liver disease.
[89] G. Shulman,et al. Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle , 2008, Diabetes.
[90] S. Mudaliar,et al. Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects. , 1995, The Journal of clinical investigation.
[91] Fritz Schick,et al. Identification and characterization of metabolically benign obesity in humans. , 2008, Archives of internal medicine.
[92] K. Petersen,et al. Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle. , 2001, The Journal of clinical investigation.
[93] Jonathan Krakoff,et al. Adiponectin and development of type 2 diabetes in the Pima Indian population , 2002, The Lancet.
[94] M. Laakso,et al. Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance , 2008, Cell.
[95] B. S. Mohammed,et al. Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity , 2009, Proceedings of the National Academy of Sciences.
[96] Y. Miyazaki,et al. Abdominal fat distribution and peripheral and hepatic insulin resistance in type 2 diabetes mellitus. , 2002, American journal of physiology. Endocrinology and metabolism.
[97] G. Marchesini,et al. Obesity-associated liver disease. , 2008, The Journal of clinical endocrinology and metabolism.
[98] B. Teusink,et al. CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice Published, JLR Papers in Press, August 16, 2003. DOI 10.1194/jlr.M300143-JLR200 , 2003, Journal of Lipid Research.
[99] Nick V. Grishin,et al. A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis , 2009, The Journal of Biological Chemistry.
[100] R. Watson,et al. GLUT4 translocation: the last 200 nanometers. , 2007, Cellular signalling.
[101] M. Ridderstråle,et al. A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans , 2009, Diabetologia.
[102] Z Trajanoski,et al. Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes. , 1999, The New England journal of medicine.
[103] J. Olefsky,et al. Effects of Weight Loss on Mechanisms of Hyperglycemia in Obese Non-Insulin-Dependent Diabetes Mellitus , 1986, Diabetes.
[104] A. Bonen,et al. Defective fatty acid uptake modulates insulin responsiveness and metabolic responses to diet in CD36-null mice. , 2002, The Journal of clinical investigation.
[105] B. Kahn,et al. Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling. , 2005, American journal of physiology. Endocrinology and metabolism.
[106] M. Daly,et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes , 2003, Nature Genetics.
[107] K. Petersen,et al. Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. , 2005, The Journal of clinical investigation.
[108] A. Baron,et al. Evidence for defects in the trafficking and translocation of GLUT4 glucose transporters in skeletal muscle as a cause of human insulin resistance. , 1998, The Journal of clinical investigation.
[109] G. Shulman,et al. n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator–Activated Receptor-α–Dependent Manner , 2007, Diabetes.
[110] S. Merali,et al. Increase in Endoplasmic Reticulum Stress–Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals , 2008, Diabetes.
[111] F. Schick,et al. High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease , 2008, Gut.
[112] L. Rossetti,et al. Mechanisms of fatty acid-induced inhibition of glucose uptake. , 1994, The Journal of clinical investigation.
[113] S. Bandinelli,et al. Diverse Effect of Inflammatory Markers on Insulin Resistance and Insulin‐Resistance Syndrome in the Elderly , 2004, Journal of the American Geriatrics Society.
[114] B. Kahn,et al. Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus. , 1999, The New England journal of medicine.
[115] D L Rothman,et al. The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2000 by The Endocrine Society Intramuscular Glycogen and Intramyocellular Lipid Utilization during Prolonged Exercise and Recovery in Man: A 13 C and 1 H Nuclear Magnetic Res , 1999 .
[116] F. Schaffner,et al. Nonalcoholic fatty liver disease. , 1986, Progress in liver diseases.
[117] R. Shulman,et al. Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. , 1992, The Journal of clinical investigation.
[118] M. Olive,et al. Life without white fat: a transgenic mouse. , 1998, Genes & development.
[119] H. Joost,et al. The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members , 2001, Molecular membrane biology.
[120] Daniel R. Dries,et al. A Single Residue in the C1 Domain Sensitizes Novel Protein Kinase C Isoforms to Cellular Diacylglycerol Production* , 2007, Journal of Biological Chemistry.
[121] R. Shulman,et al. 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus. , 1992, The Journal of clinical investigation.
[122] C. Kahn,et al. Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle. , 2000, The Journal of clinical investigation.
[123] M. Czech,et al. Threonine 1336 of the human insulin receptor is a major target for phosphorylation by protein kinase C. , 1990, Biochemistry.
[124] M. Reitman,et al. Leptin-replacement therapy for lipodystrophy. , 2002, The New England journal of medicine.
[125] A. Häkkinen,et al. Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance, and gene expression in adipose tissue in patients with type 2 diabetes. , 2004, Diabetes.
[126] G. Shulman,et al. n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner. , 2007, Diabetes.
[127] S. Lillioja,et al. Skeletal Muscle Triglyceride Levels Are Inversely Related to Insulin Action , 1997, Diabetes.
[128] C. Cobelli,et al. Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes. , 2004, Diabetes.
[129] G. Dohm,et al. Increased protein kinase C theta in skeletal muscle of diabetic patients. , 2001, Metabolism: clinical and experimental.
[130] D. Befroy,et al. Mechanism of Hepatic Insulin Resistance in Non-alcoholic Fatty Liver Disease* , 2004, Journal of Biological Chemistry.
[131] R. Bergman,et al. Free Fatty Acid as a Link in the Regulation of Hepatic Glucose Output by Peripheral Insulin , 1995, Diabetes.
[132] Yiying Zhang,et al. Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance. , 2007, The Journal of clinical investigation.
[133] K. Petersen,et al. Mechanism of free fatty acid-induced insulin resistance in humans. , 1996, The Journal of clinical investigation.
[134] S. Shoelson,et al. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. , 2005, Nature medicine.
[135] K. Petersen,et al. Low adiponectin levels in adolescent obesity: a marker of increased intramyocellular lipid accumulation. , 2003, The Journal of clinical endocrinology and metabolism.
[136] G. Shulman,et al. On Diabetes: Insulin Resistance Cellular Mechanisms of Insulin Resistance , 2022 .
[137] S. Wakil,et al. Continuous fat oxidation in acetyl–CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity , 2007, Proceedings of the National Academy of Sciences.
[138] G. Shulman,et al. Metabolic Defects in Lean Nondiabetic Offspring of NIDDM Parents: A Cross-Sectional Study , 1997, Diabetes.
[139] G. Shulman,et al. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[140] E. Kraegen,et al. Influence of Dietary Fat Composition on Development of Insulin Resistance in Rats: Relationship to Muscle Triglyceride and ω-3 Fatty Acids in Muscle Phospholipid , 1991, Diabetes.
[141] J. Olefsky,et al. Phorbol ester-mediated protein kinase C interaction with wild-type and COOH-terminal truncated insulin receptors. , 1991, The Journal of biological chemistry.
[142] L. DiPietro,et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study , 1999, Diabetologia.
[143] E. Newsholme,et al. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. , 1963, Lancet.
[144] J. Olefsky,et al. Glycemic effects of intensive caloric restriction and isocaloric refeeding in noninsulin-dependent diabetes mellitus. , 1985, The Journal of clinical endocrinology and metabolism.
[145] Jonathan C. Cohen,et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity , 2004, Hepatology.
[146] S. Shoelson,et al. Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB , 2005, Nature Medicine.