AN ELECTRICAL ARTIFICIAL PACEMAKER FOR STANDSTILL OF THE HEART

DURING A RECENT INVESTIGATION1' 23 of the use of general hypothermia for experimental intracardiac surgery, it was observed that complete standstill of the heart occurred quite frequently at very low body temperature. It was also noted that application of a stimulus, whether electrical or mechanical in character, to the region of the sinoauricular node resulted in the production of normally appearing expulsive beats. An attempt was made to develop a technic whereby frequent regular electrical stimuli of required strength and character could be applied to the sino-auricular nodal area to act as an artificial pacemaker, which might permit control of heart action for prolonged periods after cardiac arrest. In this study such an artificial pacemaker has been used for cardiac arrest in dogs at low body temperature. Our interest has been extended to the application of this principle in the control of heart action at normal body temperature. The only type of cardiac arrest which it was thought would provide a situation whereby artificial pacemaker activity could be demonstrated was