Foetal echoencephalography and Doppler ultrasonography of the middle cerebral artery in canine foetuses.

OBJECTIVES This study aimed to evaluate the characteristics of the brain and vascular indices of the middle cerebral artery of canine foetuses. METHODS Twenty-five bitches were selected. Tissue development, echogenicity, echotexture and brain echobiometric data were studied, and the major structures were identified between the 5th and 8th gestational weeks. The area and volume of the brain mass (BMA and BMV), cranial area and volume (AC and VC), brain mass index (BMI) and brain volume index (BVI) were determined. A single ultrasound examination was performed during each studied week (6th, 7th and 8th). Doppler ultrasonography was performed to assess the maximum and minimum velocity, resistance and pulsatility index of middle cerebral artery of the foetuses. RESULTS Echoencephalography was performed to evaluate the morphological characteristics of the central nervous system. Cerebral echobiometry indicated an increase in area and volume of the hemispheres and cranium (P<0·001) but no changes in BMI or BVI over the gestational period studied. Doppler ultrasonography identified increases in peak systolic velocity (P=0·0188) and end diastolic velocity (P=0·0274) and decreases in resistance index (P=0·0002) and pulsatility index (P<0·001). CLINICAL SIGNIFICANCE Echoencephalography and spectral Doppler ultrasonography of the middle cerebral artery in canine foetuses might be a useful technique for prenatal care.

[1]  M. Feliciano,et al.  Conventional and Doppler ultrasound for the differentiation of benign and malignant canine mammary tumours. , 2012, The Journal of small animal practice.

[2]  C. Gobello,et al.  Doppler ultrasonographic assessment of maternal and fetal blood flow in abnormal canine pregnancy. , 2011, Animal reproduction science.

[3]  S. Domingues,et al.  Conceptus ecobiometry and triplex Doppler ultrasonography of uterine and umbilical arteries for assessment of fetal viability in dogs. , 2010, Theriogenology.

[4]  M. Chammas,et al.  Transcranial duplex doppler ultrasonography in dogs with hydrocephalus , 2010 .

[5]  W. Thomas.  Hydrocephalus in dogs and cats. , 2010, The Veterinary clinics of North America. Small animal practice.

[6]  M. Feliciano,et al.  Ultra-sonografia bidimensional convencional, de alta resolução e tridimensional no acompanhamento da gestação em cadela , 2007 .

[7]  M. Treadwell,et al.  Middle cerebral artery peak systolic velocity: a new Doppler parameter in the assessment of growth‐restricted fetuses , 2007, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[8]  M. Kustritz.  Pregnancy diagnosis and abnormalities of pregnancy in the dog. , 2005 .

[9]  Jorge Sandoval,et al.  Prenatal sonographic diagnosis of fetal death and hydranencephaly in two Chihuahua fetuses. , 2003, Veterinary Radiology & Ultrasound.

[10]  F. M. Filho,et al.  Evolução dos índices dopplervelocimétricos da artéria cerebral média em fetos de gestantes normais , 2003 .

[11]  S. Carroll,et al.  Noninvasive diagnosis of anemia in hydrops fetalis with the use of middle cerebral artery Doppler velocity. , 2001, American journal of obstetrics and gynecology.

[12]  G. Buck,et al.  Prediction of fetal anemia with Doppler measurement of the middle cerebral artery peak systolic velocity in pregnancies complicated by maternal blood group alloimmunization or parvovirus B19 infection , 2001, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[13]  D. Buxton,et al.  Color flow Doppler imaging and Doppler spectral analysis of the brain of neonatal dogs. , 1997, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.