Detection of N7-(2-hydroxyethyl)guanine adducts in DNA and 9L cells treated with 1-(2-chloroethyl)-1-nitrosourea.

[1]  R. Giese,et al.  General method for determining ethylene oxide and related N7-guanine DNA adducts by gas chromatography-electron capture mass spectrometry. , 1995, Journal of chromatography. A.

[2]  R. Baan,et al.  Comparison of various immunochemical assays for the detection of ethylene oxide-DNA adducts with monoclonal antibodies against imidazole ring-opened N7-(2-hydroxyethyl)guanosine: application in a biological monitoring study. , 1994, Carcinogenesis.

[3]  W. Bodell,et al.  Chemical synthesis and detection of the cross-link 1-[N3-(2'-deoxycytidyl)]-2-[N1-(2'-deoxyguanosinyl)]ethane in DNA reacted with 1-(2-chloroethyl)-1-nitrosourea. , 1993, Chemical research in toxicology.

[4]  R. Tarone,et al.  Relationship between patient response in ovarian and breast cancer and platinum drug-DNA adduct formation. , 1993, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[5]  R. Baan,et al.  Determining N7-alkylguanine adducts by immunochemical methods and HPLC with electrochemical detection: applications in animal studies and in monitoring human exposure to alkylating agents. , 1993, Environmental health perspectives.

[6]  T. Skopek,et al.  Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice. , 1992, Cancer research.

[7]  R. Baan,et al.  The isolation of monoclonal antibodies selected for the detection of imidazole ring-opened N7-ethylguanine in purified DNA and in cells in situ. Crossreaction with methyl, 2-hydroxyethyl and sulphur mustard adducts. , 1991, Carcinogenesis.

[8]  W. Bodell.  Molecular dosimetry for sister-chromatid exchange induction and cytotoxicity by monofunctional and bifunctional alkylating agents. , 1990, Mutation research.

[9]  D. Ludlum.  DNA alkylation by the haloethylnitrosoureas: nature of modifications produced and their enzymatic repair or removal. , 1990, Mutation research.

[10]  R. Santella,et al.  Development of monoclonal antibodies recognizing 7-(2-hydroxyethyl)guanine and imidazole ring-opened 7-(2-hydroxyethyl)guanine. , 1990, Carcinogenesis.

[11]  B. Ames,et al.  Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection. , 1989, Carcinogenesis.

[12]  W. Bodell,et al.  Differences in DNA alkylation products formed in sensitive and resistant human glioma cells treated with N-(2-chloroethyl)-N-nitrosourea. , 1988, Cancer research.

[13]  W. Morgan,et al.  Reduced level of DNA cross-links and sister chromatid exchanges in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant rat brain tumor cells. , 1984, Cancer research.

[14]  K. Kohn,et al.  Modifications of DNA by different haloethylnitrosoureas. , 1982, Cancer research.

[15]  W. Tong,et al.  Formation of the cross-linked base, diguanylethane, in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea. , 1981, Cancer research.

[16]  K W Kohn,et al.  DNA-protein cross-linking and DNA interstrand cross-linking by haloethylnitrosoureas in L1210 cells. , 1978, Cancer research.

[17]  W. Bodell,et al.  Reduced DNA repair in mouse satellite DNA after treatment with methylmethanesulfonate, and N-methyl-N-nitrosourea. , 1976, Nucleic acids research.

[18]  R. Baan,et al.  Determination of N7-(2-hydroxyethyl)guanine by HPLC with electrochemical detection. , 1991, Chemico-biological interactions.

[19]  A. Prestayko.  Nitrosoureas : current status and new developments , 1981 .