论文信息 - Antifungal diterpenes from the bark of Cryptomeria japonica D. Don

Antifungal diterpenes from the bark of Cryptomeria japonica D. Don

Abstract Bioassay-guided isolation of compounds from n-hexane extracts of the bark of Cryptomeria japonica resulted in six abietane- and two pimarane-type diterpenoids, including a new compound, 12-methoxy-6α,11-dihydroxyabieta-8,11,13-triene. The structure of the new substance was established by spectral analyses and comparison with related compounds. The antifungal activities of these diterpenes were evaluated against the phytopathogenic fungi Alternaria alternata, Pyricularia oryzae, Rhizoctonia solani and Fusarium oxysporum. The diterpenes showed moderate antifungal activity against the fungi examined.

H. Kofujita | M. Ota | Kouetsu Takahashi | Y. Fujino

[1] Y. Hayashi,et al. A diterpene quinone from the bark of Cryptomeria japonica. , 2002, Phytochemistry.

[2] Y. Sakagami,et al. Antimicrobial activity and metalloprotease inhibition of hinokitiol-related compounds, the constituents of Thujopsis dolabrata S. and Z. hondai MAK. , 1999, Biological & pharmaceutical bulletin.

[3] Jian-Xin Li,et al. Constituents of Roots of Salvia deserta SCHANG. (Xinjiang-Danshen) , 1998 .

[4] Jim-Min Fang,et al. Abietanes and kauranes from leaves of Cryptomeria japonica , 1994 .

[5] J. S. Mossa,et al. Antibacterial diterpenes from the leaves and seeds of Juniperus excelsa M. Bieb , 1992 .

[6] E. Wenkert,et al. Cabon-13 nuclear magnetic resonance spectroscopy of naturally occurring substances. X. Pimaradienes , 1972 .

[7] M. Yamamoto,et al. Sugi (Cryptomeria japonica D. Don) bark, a potential growth substrate for soilless culture with bioactivity against some soilborne diseases , 1997 .

[8] I. Kubo,et al. Complete 1H and 13C NMR assignments of totarol and its derivatives , 1991 .