Mouse models of age-related macular degeneration.
暂无分享,去创建一个
Steven Nusinowitz | J. Heckenlively | B. Chang | John R Heckenlively | P Elizabeth Rakoczy | Meaghan J T Yu | Bo Chang | S. Nusinowitz | P. Rakoczy | M. J. Yu | P. Elizabeth Rakoczy
[1] Y Zhao,et al. Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[2] P. Campochiaro,et al. AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. , 2002, Investigative ophthalmology & visual science.
[3] R. T. Smith,et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[4] R. Ali,et al. Gene therapy for ocular angiogenesis. , 2003, Clinical science.
[5] C. Barnstable,et al. Retinal Degenerations: Biology, Diagnostics and Therapeutics , 2008 .
[6] J. Gilbert,et al. Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration , 2005, Science.
[7] Lin Chen,et al. Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[8] L A Yannuzzi,et al. Retinal choroidal anastomoses and occult choroidal neovascularization in age-related macular degeneration. , 2000, Ophthalmology.
[9] J. Ott,et al. Complement Factor H Polymorphism in Age-Related Macular Degeneration , 2005, Science.
[10] G. Travis,et al. Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[11] P T de Jong,et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration , 1995 .
[12] S. B. Smith. Evidence of a difference in photoreceptor cell loss in the peripheral versus posterior regions of the vitiligo (C57BL/6J-mi(vit)/mi(vit)) mouse retina. , 1995, Experimental eye research.
[13] J. Rakic,et al. Mice without uPA, tPA, or plasminogen genes are resistant to experimental choroidal neovascularization. , 2003, Investigative ophthalmology & visual science.
[14] S. Sanyal,et al. Development and degeneration of retina inrds mutant mice: Effects of light on the rate of degeneration in albino and pigmented homozygous and heterozygous mutant and normal mice , 1986, Vision Research.
[15] P. Campochiaro,et al. Targeted disruption of the FGF2 gene does not prevent choroidal neovascularization in a murine model. , 1998, The American journal of pathology.
[16] P. D. de Jong,et al. The APO*E3-Leiden mouse as an animal model for basal laminar deposit , 2000, The British journal of ophthalmology.
[17] T. Speed,et al. Argon laser photocoagulation-induced modification of gene expression in the retina. , 2003, Investigative ophthalmology & visual science.
[18] M. Davisson,et al. The bst locus on mouse chromosome 16 is associated with age-related subretinal neovascularization. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[19] J. Naggert,et al. Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6. , 2002, Human molecular genetics.
[20] J. Stone,et al. Mitochondrial deletions in normal and degenerating rat retina. , 2003, Advances in experimental medicine and biology.
[21] D. Turnbull,et al. Mitochondrial abnormalities in ageing macular photoreceptors. , 2001, Investigative ophthalmology & visual science.
[22] P. Campochiaro,et al. Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment. , 2002, The American journal of pathology.
[23] T. Shinohara,et al. Lens epithelium-derived growth factor: increased survival and decreased DNA breakage of human RPE cells induced by oxidative stress. , 2001, Investigative ophthalmology & visual science.
[24] D. Wallace. A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine , 2005, Annual review of genetics.
[25] M. Callow,et al. Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[26] H. Kaplan,et al. Role of Complement and Complement Membrane Attack Complex in Laser-Induced Choroidal Neovascularization1 , 2005, The Journal of Immunology.
[27] J. Slakter,et al. RETINAL ANGIOMATOUS PROLIFERATION IN AGE–RELATED MACULAR DEGENERATION , 2001, Retina.
[28] Eiji Sakurai,et al. An animal model of age-related macular degeneration in senescent Ccl-2- or Ccr-2-deficient mice , 2003, Nature Medicine.
[29] S. Cousins,et al. Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E. , 2004, Investigative ophthalmology & visual science.
[30] S. Ryan,et al. The development of an experimental model of subretinal neovascularization in disciform macular degeneration. , 1979, Transactions of the American Ophthalmological Society.
[31] T. Roderick,et al. Retinal degeneration 6 (rd6): a new mouse model for human retinitis punctata albescens. , 2000, Investigative ophthalmology & visual science.
[32] T. Roderick,et al. A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[33] Hemant Khanna,et al. Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. , 2004, Human molecular genetics.
[34] M. T. Davisson,et al. Retinal degeneration mutants in the mouse , 2002, Vision Research.
[35] C. Curcio,et al. Ultrastructural changes in Bruch's membrane of apolipoprotein E-deficient mice. , 2000, Investigative ophthalmology & visual science.
[36] M. Boulton,et al. RPE lipofuscin and its role in retinal pathobiology. , 2005, Experimental eye research.
[37] T. Mohandas,et al. Assignment of the beta-subunit of rod photoreceptor cGMP phosphodiesterase gene PDEB (homolog of the mouse rd gene) to human chromosome 4p16. , 1992, Genomics.
[38] M. S. Brown,et al. Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[39] T. Roderick,et al. Mouse model for Usher syndrome: linkage mapping suggests homology to Usher type I reported at human chromosome 11p15. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[40] P. Campochiaro,et al. Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization. , 1997, The American journal of pathology.
[41] B. Rollins,et al. Abnormalities in Monocyte Recruitment and Cytokine Expression in Monocyte Chemoattractant Protein 1–deficient Mice , 1998, The Journal of experimental medicine.
[42] J. Bennett,et al. Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. , 2003, Molecular vision.
[43] I. Constable,et al. Inhibition of angiogenesis by adenovirus-mediated sFlt-1 expression in a rat model of corneal neovascularization. , 2001, Human gene therapy.
[44] J. Sutcliffe,et al. Retinal degeneration slow (rds) in mouse results from simple insertion of a t haplotype-specific element into protein-coding exon II. , 1995, Genomics.
[45] C. Grimm,et al. A mouse model for Sorsby fundus dystrophy. , 2002, Investigative ophthalmology & visual science.
[46] J. Naggert,et al. Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice. , 2001, Human molecular genetics.
[47] S. B. Smith,et al. Effects of dark-rearing on the retinal degeneration of the C57BL/6-mivit/mivit mouse. , 1994, Experimental eye research.
[48] P. Demant,et al. A new H-2-linked mutation, rds, causing retinal degeneration in the mouse. , 1978, Tissue Antigens.
[49] Martin Friedlander,et al. MOUSE MODEL OF SUBRETINAL NEOVASCULARIZATION WITH CHOROIDAL ANASTOMOSIS , 2003, Retina.
[50] I. Constable,et al. A model for a blinding eye disease of the aged , 2004, Biogerontology.
[51] Greene Wr. Histopathology of age-related macular degeneration. , 1999, Molecular vision.
[52] D. Bok. Evidence for an inflammatory process in age-related macular degeneration gains new support. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[53] P. Campochiaro,et al. RPE cells modulate subretinal neovascularization, but do not cause regression in mice with sustained expression of VEGF. , 2003, Investigative ophthalmology & visual science.
[54] J. Nordlund,et al. The vit gene maps to the mi (microphthalmia) locus of the laboratory mouse. , 1992, The Journal of heredity.
[55] G. Eldred,et al. Retinal age pigments generated by self-assembling lysosomotropic detergents , 1993, Nature.
[56] J. Sutcliffe,et al. Identification of a photoreceptor-specific mRNA encoded by the gene responsible for retinal degeneration slow (rds) , 1989, Nature.
[57] M. Hogan. Role of the retinal pigment epithelium in macular disease. , 1972, Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology.
[58] W R Green,et al. Age-related Macular Degeneration Histopathologic Studies: The 1992 Lorenz E. Zimmerman Lecture , 1993, Ophthalmology.
[59] D. Birch,et al. Insights into the Function of Rim Protein in Photoreceptors and Etiology of Stargardt's Disease from the Phenotype in abcr Knockout Mice , 1999, Cell.
[60] R. Radu,et al. Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[61] K. Ley,et al. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[62] I. Constable,et al. Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model. , 2002, The American journal of pathology.
[63] Donald J Zack,et al. Increased expression of VEGF in retinal pigmented epithelial cells is not sufficient to cause choroidal neovascularization , 2004, Journal of cellular physiology.
[64] R. Obata,et al. Subconjunctival administration of bucillamine suppresses choroidal neovascularization in rat. , 2002, Investigative ophthalmology & visual science.
[65] R. D'Amato,et al. Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium. , 2001, The American journal of pathology.
[66] E. Scott,et al. The role of adult bone marrow-derived stem cells in choroidal neovascularization. , 2003, Investigative ophthalmology & visual science.
[67] J. Sutcliffe,et al. The human retinal degeneration slow (RDS) gene: chromosome assignment and structure of the mRNA. , 1991, Genomics.