Sputum eosinophil counts and eosinophil cationic protein levels in cough‐variant asthma and in classic asthma, and their relationships to airway hypersensitivity or maximal airway response to methacholine

Background:  The aims of this study were to compare the degree of airway inflammation in cough‐variant asthma (CVA) with that in classic asthma (CA), and to examine the relationship between airway inflammation and airway hypersensitivity or maximal airway response to methacholine in both conditions.

[1]  Y. Koh,et al.  The importance of maximal airway response to methacholine in the prediction of wheezing development in patients with cough‐variant asthma , 2002, Allergy.

[2]  A. Jang Nasal eosinophilic inflammation contributes to bronchial hyperresponsiveness in patients with allergic rhinitis. , 2002, Journal of Korean medical science.

[3]  T. Carrillo,et al.  Sputum eosinophilia and maximal airway narrowing in Dermatophagoides pteronyssinus allergic rhinitis patients: only rhinitis or rhinitis plus mild asthma? , 2002, Chest.

[4]  R. Louis,et al.  Sputum eosinophil count in a large population of patients with mild to moderate steroid‐naive asthma: distribution and relationship with methacholine bronchial hyperresponsiveness , 2002, Allergy.

[5]  H. Matsumoto,et al.  A Study of Clinical Features of Cough Variant Asthma , 2001, International Archives of Allergy and Immunology.

[6]  M. Kitaichi,et al.  Airway remodelling in cough-variant asthma , 2000, The Lancet.

[7]  B. García,et al.  Airway inflammation in asthma and perennial allergic rhinitis. Relationship with nonspecific bronchial responsiveness and maximal airway narrowing , 2000, Allergy.

[8]  R. Djukanović,et al.  The relationship between airways inflammation and asthma severity. , 2000, American journal of respiratory and critical care medicine.

[9]  S. Peters,et al.  Airway remodeling and persistent airway obstruction in asthma. , 1999, The Journal of allergy and clinical immunology.

[10]  J. Marín,et al.  Relationship between induced sputum cell counts and fluid-phase eosinophil cationic protein and clinical or physiologic profiles in mild asthma. , 1999, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[11]  H. Hoogsteden,et al.  Eosinophils in the bronchial mucosa in relation to methacholine dose-response curves in atopic asthma. , 1999, Journal of applied physiology.

[12]  M. Bende,et al.  Sensory hyperreactivity – a possible mechanism underlying cough and asthma‐like symptoms , 1998, Allergy.

[13]  R. Djukanović,et al.  Sputum eosinophilia is more closely associated with airway responsiveness to bradykinin than methacholine in asthma. , 1998, The European respiratory journal.

[14]  A. Niimi,et al.  Eosinophilic inflammation in cough variant asthma. , 1998, The European respiratory journal.

[15]  V. Brusasco,et al.  Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma. , 1998, American journal of respiratory and critical care medicine.

[16]  J. Drazen,et al.  Inflammation and airway function in asthma: what you see is not necessarily what you get. , 1998, American journal of respiratory and critical care medicine.

[17]  P. Gibson,et al.  A systematic evaluation of mechanisms in chronic cough. , 1997, American journal of respiratory and critical care medicine.

[18]  A. James,et al.  The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics. , 1997, The European respiratory journal.

[19]  R. Duranti,et al.  Role of sputum differential cell count in detecting airway inflammation in patients with chronic bronchial asthma or COPD. , 1996, Thorax.

[20]  F. Hargreave,et al.  Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements. , 1996, American journal of respiratory and critical care medicine.

[21]  J. Bousquet,et al.  Eosinophil inflammation in asthma. , 1994, American journal of respiratory and critical care medicine.

[22]  D. Lim,et al.  Normal Predicted values of Pulmonary function Test in Korean Primary School-Aged Children , 1993 .

[23]  A. James,et al.  Maximal airway narrowing in a general population. , 1992, The American review of respiratory disease.

[24]  P. Paré,et al.  A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. , 1992, The American review of respiratory disease.

[25]  H. Smith Asthma, inflammation, eosinophils and bronchial hyperresponsiveness , 1992, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[26]  O'Connell Ej,et al.  Cough-type asthma: a review. , 1991 .

[27]  E. O'connell,et al.  Cough-type asthma: a review. , 1991, Annals of allergy.

[28]  R. Irwin,et al.  Chronic cough. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. , 1990, The American review of respiratory disease.

[29]  P. Sterk,et al.  Bronchial hyperresponsiveness: the need for a distinction between hypersensitivity and excessive airway narrowing. , 1989, The European respiratory journal.

[30]  A. Wardlaw,et al.  Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. , 1988, The American review of respiratory disease.

[31]  P. Paré,et al.  Mechanics of airway narrowing. , 2015 .

[32]  P. O'Byrne,et al.  The origin of airway hyperresponsiveness. , 1986, The Journal of allergy and clinical immunology.

[33]  P. Sterk,et al.  Maximal airway narrowing in humans in vivo. Histamine compared with methacholine. , 1986, The American review of respiratory disease.

[34]  L. Holinger Chronic cough in infants and children , 1986, The Laryngoscope.

[35]  S. Spector,et al.  Standardization of bronchial inhalation challenge procedures. , 1975, The Journal of allergy and clinical immunology.