Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse
暂无分享,去创建一个
J. Vincent | Y. Hérault | H. Meziane | H. Stunnenberg | R. Roepman | P. Billuart | M. Selloum | S. Marouillat | F. Laumonnier | P. Hamel | R. Thepault | M. Birling | G. Iacono | K. Mittal | O. Dorseuil | N. Nadif Kasri | J. van Rhijn | J. Rucci | R. Montjean | M. Selten | D. Ung | E. Blanchard | A. Fleet | M. Papon | A. Lux | S. Martin
[1] R. Reddy,et al. Association of genes with phenotype in autism spectrum disorder , 2019, Aging.
[2] T. Abel,et al. Home-cage hypoactivity in mouse genetic models of autism spectrum disorder , 2019, Neurobiology of Learning and Memory.
[3] Kuniaki Saito,et al. Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker , 2019, Scientific Reports.
[4] Chengji J. Zhou,et al. Impaired neurodevelopmental pathways in autism spectrum disorder: a review of signaling mechanisms and crosstalk , 2019, Journal of Neurodevelopmental Disorders.
[5] Christopher W. N. Saville,et al. Cognitive endophenotypes of attention deficit/hyperactivity disorder and intra-subject variability in patients with autism spectrum disorder , 2016, Biological Psychology.
[6] Lucia Margari,et al. A review of executive function deficits in autism spectrum disorder and attention-deficit/hyperactivity disorder , 2016, Neuropsychiatric disease and treatment.
[7] Kechun Zhou,et al. Sonic hedgehog is a regulator of extracellular glutamate levels and epilepsy , 2016, EMBO reports.
[8] Yingxi Lin,et al. Npas4: Linking Neuronal Activity to Memory , 2016, Trends in Neurosciences.
[9] P. J. Sjöström,et al. Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling , 2016, Science.
[10] C. Webber,et al. Systematic Phenomics Analysis Deconvolutes Genes Mutated in Intellectual Disability into Biologically Coherent Modules. , 2016, American journal of human genetics.
[11] Heike Tost,et al. Working memory genetics in schizophrenia and related disorders: An RDoC perspective , 2016, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[12] J. Lippincott-Schwartz,et al. Dendrosomatic Sonic Hedgehog Signaling in Hippocampal Neurons Regulates Axon Elongation , 2015, The Journal of Neuroscience.
[13] Mriganka Sur,et al. Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders , 2015, Science.
[14] L. Vissers,et al. Genetic studies in intellectual disability and related disorders , 2015, Nature Reviews Genetics.
[15] Michael M. Halassa,et al. Thalamic reticular impairment underlies attention deficit in Ptchd1Y/− mice , 2015, Nature.
[16] C. Cytrynbaum,et al. Phenotypic spectrum associated with PTCHD1 deletions and truncating mutations includes intellectual disability and autism spectrum disorder , 2015, Clinical genetics.
[17] T. Bourgeron. From the genetic architecture to synaptic plasticity in autism spectrum disorder , 2015, Nature Reviews Neuroscience.
[18] R. Huganir,et al. Glutamate synapses in human cognitive disorders. , 2015, Annual review of neuroscience.
[19] Daniel H. Geschwind,et al. Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders , 2015, Nature Reviews Genetics.
[20] Ed S. Lein,et al. Spatiotemporal dynamics of the postnatal developing primate brain transcriptome , 2015, Human molecular genetics.
[21] Steve D. M. Brown,et al. Applying the ARRIVE Guidelines to an In Vivo Database , 2015, PLoS biology.
[22] A. Battaglia,et al. Contribution of common and rare variants of the PTCHD1 gene to autism spectrum disorders and intellectual disability , 2015, European Journal of Human Genetics.
[23] S. Linnarsson,et al. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq , 2015, Science.
[24] A. V. Vulto-van Silfhout,et al. Homozygous SLC6A17 mutations cause autosomal-recessive intellectual disability with progressive tremor, speech impairment, and behavioral problems. , 2015, American journal of human genetics.
[25] K. Friend,et al. X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes , 2015, Molecular Psychiatry.
[26] D. Geschwind,et al. The emerging picture of autism spectrum disorder: genetics and pathology. , 2015, Annual review of pathology.
[27] M. Kolář,et al. DISP3 promotes proliferation and delays differentiation of neural progenitor cells , 2014, FEBS letters.
[28] F. Bunz,et al. A PTCH1 Homolog Transcriptionally Activated by p53 Suppresses Hedgehog Signaling* , 2014, The Journal of Biological Chemistry.
[29] Alan R. Mardinly,et al. Npas4 Regulates Excitatory-Inhibitory Balance within Neural Circuits through Cell-Type-Specific Gene Programs , 2014, Cell.
[30] Allan R. Jones,et al. Transcriptional Landscape of the Prenatal Human Brain , 2014, Nature.
[31] A. McMahon,et al. Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning , 2013, Development.
[32] A. Koleske. Molecular mechanisms of dendrite stability , 2013, Nature Reviews Neuroscience.
[33] Mark P. Mattson,et al. Sonic hedgehog regulates presynaptic terminal size, ultrastructure and function in hippocampal neurons , 2012, Journal of Cell Science.
[34] Richard D Emes,et al. Evolution of synapse complexity and diversity. , 2012, Annual review of neuroscience.
[35] Y. Hérault,et al. Highly‐efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background , 2012, Genesis.
[36] Allan R. Jones,et al. Large-Scale Cellular-Resolution Gene Profiling in Human Neocortex Reveals Species-Specific Molecular Signatures , 2012, Cell.
[37] M. Mattson,et al. Subcellular localization of patched and smoothened, the receptors for sonic hedgehog signaling, in the hippocampal neuron , 2011, The Journal of comparative neurology.
[38] Hans van Bokhoven,et al. Genetic and epigenetic networks in intellectual disabilities. , 2011, Annual review of genetics.
[39] M. Mattson,et al. Sonic hedgehog distribution within mature hippocampal neurons , 2011, Communicative & integrative biology.
[40] P. Demougin,et al. Deletion in Xp22.11: PTCHD1 is a candidate gene for X‐linked intellectual disability with or without autism , 2011, Clinical genetics.
[41] Chi-Chung Hui,et al. Disruption at the Ptchd1 Locus on Xp22.11 in Autism Spectrum Disorder and Intellectual Disability Nih Public Access , 2010 .
[42] G. Kreiman,et al. Widespread transcription at neuronal activity-regulated enhancers , 2010, Nature.
[43] S. Hymowitz,et al. The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling , 2009, Nature Structural &Molecular Biology.
[44] F. Charron,et al. Sonic Hedgehog Guides Axons through a Noncanonical, Src-Family-Kinase-Dependent Signaling Pathway , 2009, Neuron.
[45] Xiaohui Xie,et al. MotifMap: a human genome-wide map of candidate regulatory motif sites , 2009, Bioinform..
[46] Athar N. Malik,et al. Activity-dependent regulation of inhibitory synapse development by Npas4 , 2008, Nature.
[47] Li Zhang,et al. Male germ cell-specific expression of a novel Patched-domain containing gene Ptchd3. , 2007, Biochemical and biophysical research communications.
[48] T. Dresbach,et al. Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding , 2004, Molecular and Cellular Neuroscience.
[49] N. Ziv,et al. Postsynaptic Density Assembly Is Fundamentally Different from Presynaptic Active Zone Assembly , 2004, The Journal of Neuroscience.
[50] R. Petralia,et al. NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex , 2003, Nature Cell Biology.
[51] A. Graybiel,et al. A measure of striatal function predicts motor stereotypy , 2000, Nature Neuroscience.