The transcription factor RFX5 coordinates antigen-presenting function and resistance to nutrient stress in synovial macrophages

[1]  Jonathan D. Curtis,et al.  A common framework of monocyte-derived macrophage activation , 2022, Science Immunology.

[2]  H. Kettenmann,et al.  Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model. , 2022, Cell reports.

[3]  C. Weyand,et al.  Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation , 2021, Nature Immunology.

[4]  Hao Li,et al.  Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis , 2021, Nature Communications.

[5]  B. Le Goff,et al.  Novel insights into macrophage diversity in rheumatoid arthritis synovium. , 2021, Autoimmunity reviews.

[6]  L. Tian,et al.  Succinyl-CoA Ligase Deficiency in Pro-inflammatory and Tissue-Invasive T Cells. , 2020, Cell metabolism.

[7]  C. Weyand,et al.  The immunology of rheumatoid arthritis , 2020, Nature Immunology.

[8]  P. Carmeliet,et al.  Macrophage-derived glutamine boosts satellite cells and muscle regeneration , 2020, Nature.

[9]  M. Rossol,et al.  Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis , 2020, Nature Communications.

[10]  Q. Su,et al.  Cytokines and Abnormal Glucose and Lipid Metabolism , 2019, Front. Endocrinol..

[11]  Amber Dance.  Core Concept: Cells nibble one another via the under-appreciated process of trogocytosis , 2019, Proceedings of the National Academy of Sciences.

[12]  L. Tian,et al.  The DNA Repair Nuclease MRE11A Functions as a Mitochondrial Protector and Prevents T Cell Pyroptosis and Tissue Inflammation. , 2019, Cell metabolism.

[13]  Shuyang Zhang,et al.  Identification and validation of four hub genes involved in the plaque deterioration of atherosclerosis , 2019, Aging.

[14]  Friedrich Paulsen,et al.  Locally renewing resident synovial macrophages provide a protective barrier for the joint , 2019, Nature.

[15]  L. Ivashkiv,et al.  Interferon target-gene expression and epigenomic signatures in health and disease , 2019, Nature Immunology.

[16]  F. Greten,et al.  Inflammation and Cancer: Triggers, Mechanisms, and Consequences. , 2019, Immunity.

[17]  D. Vivien,et al.  HLA-Class II Artificial Antigen Presenting Cells in CD4+ T Cell-Based Immunotherapy , 2019, Front. Immunol..

[18]  G. Rätsch,et al.  HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness , 2019, Science Translational Medicine.

[19]  R. Wyatt,et al.  Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease , 2019, Nature Immunology.

[20]  F. Ginhoux,et al.  Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches , 2019, Science.

[21]  Maxim N. Artyomov,et al.  Itaconate: the poster child of metabolic reprogramming in macrophage function , 2019, Nature Reviews Immunology.

[22]  Jocelyn T. Kim,et al.  T cell antigen discovery via trogocytosis , 2019, Nature Methods.

[23]  Eyal Amiel,et al.  Regulation of Dendritic Cell Immune Function and Metabolism by Cellular Nutrient Sensor Mammalian Target of Rapamycin (mTOR) , 2019, Front. Immunol..

[24]  Ping-Chih Ho,et al.  Immunity, Hypoxia and Metabolism - the ménage à trois of cancer: implications for immunotherapy. , 2019, Physiological reviews.

[25]  P. Feng,et al.  Interplay between Cellular Metabolism and Cytokine Responses during Viral Infection , 2018, Viruses.

[26]  A. Lerman,et al.  Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation. , 2018, Cell metabolism.

[27]  Nir Hacohen,et al.  Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry , 2019, Nature Immunology.

[28]  R. Darnell,et al.  Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data , 2018, Arthritis & rheumatology.

[29]  Edward T Chouchani,et al.  Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 , 2018, Nature.

[30]  T. Assimes,et al.  Hypermetabolic macrophages in rheumatoid arthritis and coronary artery disease due to glycogen synthase kinase 3b inactivation , 2018, Annals of the rheumatic diseases.

[31]  Andreas Radbruch,et al.  Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint , 2017, Annals of the rheumatic diseases.

[32]  E. Matteson,et al.  Metabolic control of the scaffold protein TKS5 in tissue-invasive, pro-inflammatory T cells , 2017, Nature Immunology.

[33]  D. Greiner,et al.  Humanized Mouse Models of Clinical Disease. , 2017, Annual review of pathology.

[34]  Vivien A. C. Schoonenberg,et al.  β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance , 2016, Cell.

[35]  R. Xavier,et al.  Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages , 2016, Cell.

[36]  A. Mantovani,et al.  Macrophage heterogeneity in the context of rheumatoid arthritis , 2016, Nature Reviews Rheumatology.

[37]  T. Assimes,et al.  The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease , 2016, The Journal of experimental medicine.

[38]  P. Roche,et al.  The ins and outs of MHC class II-mediated antigen processing and presentation , 2015, Nature Reviews Immunology.

[39]  Abhishek K. Jha,et al.  Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization. , 2015, Immunity.

[40]  Robert A. Egnatchik,et al.  Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. , 2015, Cancer cell.

[41]  M. Sieweke,et al.  Monocytes compensate Kupffer cell loss during bacterial infection. , 2015, Immunity.

[42]  E. Gautier,et al.  Understanding macrophage diversity at the ontogenic and transcriptomic levels , 2014, Immunological reviews.

[43]  J. Knight,et al.  Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach , 2014, Genome Biology.

[44]  R. Guthke,et al.  Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation , 2014, Arthritis Research & Therapy.

[45]  Andreas Meisel,et al.  Sugar for the brain: the role of glucose in physiological and pathological brain function , 2013, Trends in Neurosciences.

[46]  Liang Zheng,et al.  Succinate is an inflammatory signal that induces IL-1β through HIF-1α , 2013, Nature.

[47]  Amin R. Mazloom,et al.  Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages , 2012, Nature Immunology.

[48]  D. Greiner,et al.  Humanized mice for immune system investigation: progress, promise and challenges , 2012, Nature Reviews Immunology.

[49]  Marc D. Perry,et al.  ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia , 2012, Genome research.

[50]  Jos W. M. van der Meer,et al.  Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases , 2012, Nature Reviews Drug Discovery.

[51]  Ming Zhao,et al.  The chemokine CCL18 causes maturation of cultured monocytes to macrophages in the M2 spectrum , 2012, Immunology.

[52]  M. Larocca,et al.  Nutritional stress in eukaryotic cells: oxidative species and regulation of survival in time of scarceness. , 2012, Molecular genetics and metabolism.

[53]  W. Schamel,et al.  A new vampire saga: the molecular mechanism of T cell trogocytosis. , 2011, Immunity.

[54]  Mark M. Davis,et al.  Interrogating the repertoire: broadening the scope of peptide–MHC multimer analysis , 2011, Nature Reviews Immunology.

[55]  J. Dick,et al.  Bone Marrow-derived Human Hematopoietic Stem Cells Engraft NOD/SCID Mice and Traffic Appropriately to an Inflammatory Stimulus in the Joint , 2010, The Journal of Rheumatology.

[56]  R. Deberardinis,et al.  Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis , 2007, Proceedings of the National Academy of Sciences.

[57]  J. Xiang,et al.  Bidirectional membrane molecule transfer between dendritic and T cells. , 2007, Biochemical and biophysical research communications.

[58]  B. W. Schreurs,et al.  Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, Toll-like receptors and rheumatoid synovial fluid , 2006, BMC Immunology.