Self-assembling complexes for gene delivery : from laboratory to clinical trial
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Partial table of contents: PRINCIPLES OF SELF-ASSEMBLY. Polymorphism of Lipids, Nucleic Acids, and their Interactions (D. Lasic, et al.). Self-Assembly of Bacteriophage (M. Burbea P. Prevelige). NATURAL MECHANISMS FOR GENE-DELIVERY TO CELLS. Endocytosis: An Overview (V. Slepnev P. De Camilli). NOVEL SYSTEMS USING CATIONIC LIPOSOMES. Novel Supramolecular Assemblies for Gene Delivery (F.-P. Yang L. Huang). POLYELECTROLYTE DNA COMPLEXES. Cationic Block Copolymers as Self-Assembling Vectors for Gene Delivery (L. Seymour, et al.). Cellular Internalization and Fate of Polycation-DNA Complexes (C. Pouton, et al.). SYSTEMIC BIODISTRIBUTION OF DRUG DELIVERY SYSTEMS. In Vitro and In Vivo Availability of Liposomes (V. Torchilin). TARGETING OF CONJUGATES FOR GENE DELIVERY. Polylysine-Conjugate Based DNA Delivery (E. Wagner). Peptides and Fusion Proteins as Modular DNA Carriers (W. Wels J. Fominaya). NEW APPORACHES TO GENE DELIVERY. Semi-Synthetic Systems for Gene Delivery (C. Hodgson, et al.). CLINICAL EVALUATION. Cystic Fibrosis Clinical Trials (D. Geddes E. Alton). Index.