Spherically symmetric volume elements as basis functions for image reconstructions in computed laminography.

BACKGROUND Laminography is a tomographic technique that allows three-dimensional imaging of flat and elongated objects that stretch beyond the extent of a reconstruction volume. Laminography images can be reconstructed using iterative algorithms based on the Kaczmarz method. OBJECTIVE This study aims to develop and demonstrate a new reconstruction algorithm that may provide superior image reconstruction quality for this challenged imaging application. METHODS The images are initially represented using the coefficients over basis functions, which are typically piecewise constant functions (voxels). By replacing voxels with spherically symmetric volume elements (blobs) based on the generalized Kaiser-Bessel window functions, the images are reconstructed using this new adapted version of the algebraic image reconstruction technique. RESULTS Band-limiting properties of blob functions are beneficial particular in the case of noisy projections and with only a limited number of available projections. Study showed that using blob basis functions improved full-width-at-half-maximum resolution from 10.2±1.0 to 9.9±0.9 (p < 0.001). Signal-to-noise ratio also improved from 16.1 to 31.0. The increased computational demand per iteration was compensated by using a faster convergence rate, such that the overall performance is approximately identical for blobs and voxels. CONCLUSIONS Despite the higher complexity, tomographic reconstruction from computed laminography data should be implemented using blob basis functions, especially if noisy data is expected.

[1]  P. Cloetens,et al.  Laminographic imaging using synchrotron radiation – challenges and opportunities , 2013 .

[2]  J M Carazo,et al.  Exploiting desktop supercomputing for three-dimensional electron microscopy reconstructions using ART with blobs. , 2009, Journal of structural biology.

[3]  Ian Sinclair,et al.  Recent Advances in X-ray Cone-beam Computed Laminography. , 2016, Journal of X-ray science and technology.

[4]  D. DeRosier,et al.  The reconstruction of a three-dimensional structure from projections and its application to electron microscopy , 1970, Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences.

[6]  J. Zhou,et al.  X-ray computed laminography: an approach of computed tomography for applications with limited access , 1999 .

[7]  A. Kak,et al.  Simultaneous Algebraic Reconstruction Technique (SART): A Superior Implementation of the Art Algorithm , 1984, Ultrasonic imaging.

[8]  Edgar Garduño,et al.  Optimization of basis functions for both reconstruction and visualization , 2001, IWCIA.

[10]  Tim Dahmen,et al.  Combined Scanning Transmission Electron Microscopy Tilt- and Focal Series , 2014, Microscopy and Microanalysis.

[11]  S. Shapiro,et al.  An Analysis of Variance Test for Normality (Complete Samples) , 1965 .

[12]  R M Lewitt,et al.  Multidimensional digital image representations using generalized Kaiser-Bessel window functions. , 1990, Journal of the Optical Society of America. A, Optics and image science.

[13]  J. Zhou,et al.  Computed laminography for materials testing , 1996 .

[14]  A. Lent,et al.  ART: Mathematics and applications a report on the mathematical foundations and on the applicability to real data of the algebraic reconstruction techniques , 1973 .

[15]  John B. Shoven,et al.  I , Edinburgh Medical and Surgical Journal.

[16]  L.M. Popescu,et al.  Ray tracing through a grid of blobs , 2004, IEEE Symposium Conference Record Nuclear Science 2004..

[17]  M. Maisl,et al.  Computed Laminography for X-ray Inspection of Lightweight Constructions , 2010 .

[18]  Tim Dahmen,et al.  The Ettention software package. , 2016, Ultramicroscopy.

[19]  Christian Schorr,et al.  A Semi-Discrete Landweber–Kaczmarz Method for Cone Beam Tomography and Laminography Exploiting Geometric Prior Information , 2016 .

[20]  Robert M. Lewitt,et al.  Practical considerations for 3-D image reconstruction using spherically symmetric volume elements , 1996, IEEE Trans. Medical Imaging.

[21]  D. G. Grant Tomosynthesis: a three-dimensional radiographic imaging technique. , 1972, IEEE transactions on bio-medical engineering.

[22]  R. Lewitt Alternatives to voxels for image representation in iterative reconstruction algorithms , 1992, Physics in medicine and biology.

[23]  Peter Cloetens,et al.  Nano-laminography for three-dimensional high-resolution imaging of flat specimens , 2013 .

[24]  Jack Bresenham,et al.  Algorithm for computer control of a digital plotter , 1965, IBM Syst. J..

[25]  P. Mikulík,et al.  High-resolution three-dimensional imaging by synchrotron-radiation computed laminography , 2006, SPIE Optics + Photonics.

[26]  R. Rosenthal,et al.  Meta-analysis: recent developments in quantitative methods for literature reviews. , 2001, Annual review of psychology.

[27]  J M Carazo,et al.  3D reconstruction in electron microscopy using ART with smooth spherically symmetric volume elements (blobs). , 1998, Ultramicroscopy.