The Role of Wharton’s Jelly Mesenchymal Stem Cells in Diabetes Mellitus

Diabetes mellitus is one of the most common chronic disorders in the world, which characterized by progressive destruction of insulin-producing beta cells in the pancreatic islets of Langerhans. Currently, great interest has been generated in human umbilical cord mesenchymal stem cells (huMSCs), which are potential applications for the treatment of diabetes mellitus. Therefore, the aim of this study is that WJMSCs will be induced to differentiate into pancreatic beta-like cells in vitro. At this stage, we isolated and induced cultured huMSCs from the UC’s WJ under specific culture conditions, and then the morphology of huMSCs were monitored under an inverted phase contrast microscope. We envision that these results will provide a basis for the potential use of Wharton’s Jelly MSCs as a source in stem cell-based therapy for diabetes mellitus.

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