Reciprocal Regulation of Protein Synthesis and Carbon Metabolism for Thylakoid Membrane Biogenesis

A subunit of the chloroplast pyruvate dehydrogenase complex, which serves as a metabolic enzyme, also has a dual function as an RNA-binding protein and influences mRNA translation.

[1]  Y. Poirier,et al.  The protein acetylome and the regulation of metabolism. , 2012, Trends in plant science.

[2]  L. Simpson,et al.  A 100-kD complex of two RNA-binding proteins from mitochondria of Leishmania tarentolae catalyzes RNA annealing and interacts with several RNA editing components. , 2003, RNA.

[3]  A. Blomme,et al.  Proteomic and functional characterization of a Chlamydomonas reinhardtii mutant lacking the mitochondrial alternative oxidase 1. , 2010, Journal of proteome research.

[4]  D. Leister,et al.  Arabidopsis CSP41 proteins form multimeric complexes that bind and stabilize distinct plastid transcripts , 2011, Journal of experimental botany.

[5]  A. Barkan.  Expression of Plastid Genes: Organelle-Specific Elaborations on a Prokaryotic Scaffold1 , 2011, Plant Physiology.

[6]  W. Martin,et al.  A proteomic survey of Chlamydomonas reinhardtii mitochondria sheds new light on the metabolic plasticity of the organelle and on the nature of the alpha-proteobacterial mitochondrial ancestor. , 2009, Molecular biology and evolution.

[7]  J. Cieśla.  Metabolic enzymes that bind RNA: yet another level of cellular regulatory network? , 2006, Acta biochimica Polonica.

[8]  C. Benning.  Mechanisms of lipid transport involved in organelle biogenesis in plant cells. , 2009, Annual review of cell and developmental biology.

[9]  D. Oliver,et al.  The Role of Acetyl-Coenzyme A Synthetase in Arabidopsis1[OA] , 2008, Plant Physiology.

[10]  M. Spalding.  Chapter 8 – The CO2-Concentrating Mechanism and Carbon Assimilation , 2009 .

[11]  R. Perham,et al.  Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions. , 2000, Annual review of biochemistry.

[12]  J. Rochaix,et al.  Characterization of Mbb1, a nucleus-encoded tetratricopeptide-like repeat protein required for expression of the chloroplast psbB/psbT/psbH gene cluster in Chlamydomonas reinhardtii. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[13]  B. Mooney,et al.  Cloning and characterization of the dihydrolipoamide S-acetyltransferase subunit of the plastid pyruvate dehydrogenase complex (E2) from Arabidopsis. , 1999, Plant physiology.

[14]  W. Martin,et al.  Evolution of the enzymes of the citric acid cycle and the glyoxylate cycle of higher plants. A case study of endosymbiotic gene transfer. , 2002, European journal of biochemistry.

[15]  Daniel A. Colón-Ramos,et al.  FISH and immunofluorescence staining in Chlamydomonas. , 2011, Methods in molecular biology.

[16]  Eszter Nagy,et al.  Glyceraldehyde-3-phosphate Dehydrogenase Selectively Binds AU-rich RNA in the NAD+-binding Region (Rossmann Fold) (*) , 1995, The Journal of Biological Chemistry.

[17]  R. McKay,et al.  Composition and function of pyrenoids : Cytochemical and immunocytochemical approaches , 1991 .

[18]  W. Zerges,et al.  Photosystem II Assembly and Repair Are Differentially Localized in Chlamydomonas[W] , 2007, The Plant Cell Online.

[19]  D. Randall,et al.  Regulation of pyruvate dehydrogenase complex activity in plant cells. , 2003, European journal of biochemistry.

[20]  J. Rochaix,et al.  Low Density Membranes Are Associated with RNA-binding Proteins and Thylakoids in the Chloroplast of Chlamydomonas reinhardtii , 1998, The Journal of cell biology.

[21]  S. Rawsthorne.  Carbon flux and fatty acid synthesis in plants. , 2002, Progress in lipid research.

[22]  S. Mayfield,et al.  Arabidopsis thaliana mutants reveal a role for CSP41a and CSP41b, two ribosome-associated endonucleases, in chloroplast ribosomal RNA metabolism , 2008, Plant Molecular Biology.

[23]  J. Erickson,et al.  Characterization of photosystem II mutants of Chlamydomonas reinhardii lacking the psbA gene , 1986, Plant Molecular Biology.

[24]  J. Nickelsen,et al.  Identification of cis-Acting RNA Leader Elements Required for Chloroplast psbD Gene Expression in Chlamydomonas , 1999, Plant Cell.

[25]  James K. Stoops,et al.  The remarkable structural and functional organization of the eukaryotic pyruvate dehydrogenase complexes , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[26]  E. Aro,et al.  Strategies for psbA gene expression in cyanobacteria, green algae and higher plants: from transcription to PSII repair. , 2012, Biochimica et biophysica acta.

[27]  Robert Fox,et al.  Getting There From Here , 1998 .

[28]  M G Rossmann,et al.  Comparison of super-secondary structures in proteins. , 1973, Journal of molecular biology.

[29]  S. Brunak,et al.  Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. , 2000, Journal of molecular biology.

[30]  W. Sakamoto,et al.  Protein quality control in chloroplasts: a current model of D1 protein degradation in the photosystem II repair cycle. , 2009, Journal of biochemistry.

[31]  K. P. Watkins,et al.  CRS1, a Chloroplast Group II Intron Splicing Factor, Promotes Intron Folding through Specific Interactions with Two Intron Domainsw⃞ , 2005, The Plant Cell Online.

[32]  J. Marrison,et al.  Subcellular Visualization of Gene Transcripts Encoding Key Proteins of the Chlorophyll Accumulation Process in Developing Chloroplasts , 1996, Plant physiology.

[33]  J. Wilce,et al.  Sequence requirements for RNA binding by HuR and AUF1. , 2012, Journal of biochemistry.

[34]  J. Nickelsen,et al.  The Nac2 gene of Chlamydomonas encodes a chloroplast TPR‐like protein involved in psbD mRNA stability , 2000, The EMBO journal.

[35]  F. Chueh,et al.  Nuclear localization of pyruvate dehydrogenase complex-E2 (PDC-E2), a mitochondrial enzyme, and its role in signal transducer and activator of transcription 5 (STAT5)-dependent gene transcription. , 2011, Cellular signalling.

[36]  R. Perham,et al.  Genetic reconstruction and functional analysis of the repeating lipoyl domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. , 1985, Journal of molecular biology.

[37]  D. Meinke,et al.  Integrating the Genetic and Physical Maps of Arabidopsis thaliana: Identification of Mapped Alleles of Cloned Essential (EMB) Genes , 2009, PloS one.

[38]  J. Chory,et al.  Coordination of gene expression between organellar and nuclear genomes , 2008, Nature Reviews Genetics.

[39]  C. Schwarz,et al.  An intermolecular disulfide-based light switch for chloroplast psbD gene expression in Chlamydomonas reinhardtii. , 2012, The Plant journal : for cell and molecular biology.

[40]  P. Gardeström,et al.  Isolation, Purification, and Characterization of Mitochondria from Chlamydomonas reinhardtii , 1995, Plant physiology.

[41]  C. Ouzounis,et al.  Nucleic acid-binding metabolic enzymes: Living fossils of stereochemical interactions? , 1995, Journal of Molecular Evolution.

[42]  J. Erickson,et al.  Lack of the D2 protein in a Chlamydomonas reinhardtii psbD mutant affects photosystem II stability and D1 expression , 1986, The EMBO journal.

[43]  H. Weiner,et al.  NAD(P)+ Binding to Dehydrogenases , 2005 .

[44]  Synthesis of the D2 Protein of Photosystem II in Chlamydomonas Is Controlled by a High Molecular Mass Complex Containing the RNA Stabilization Factor Nac2 and the Translational Activator RBP40 , 2007, The Plant Cell Online.

[45]  D. Herrin,et al.  Translational regulation of chloroplast gene expression during the light-dark cell cycle of Chlamydomonas: evidence for control by ATP/energy supply. , 1990, Biochemical and biophysical research communications.

[46]  Enrichment of native, high molecular weight ribonucleoprotein complexes from chloroplasts by consecutive gel filtration steps , 2010 .

[47]  M. Hanson,et al.  Chloroplast RNA metabolism. , 2010, Annual review of plant biology.

[48]  E. H. Harris.  The Chlamydomonas sourcebook , 2009 .

[49]  H. Lambers,et al.  Disruption of ptLPD1 or ptLPD2, Genes That Encode Isoforms of the Plastidial Lipoamide Dehydrogenase, Confers Arsenate Hypersensitivity in Arabidopsis1[W][OA] , 2010, Plant Physiology.

[50]  M. Piotrowski,et al.  Cyanide Metabolism in Higher Plants: Cyanoalanine Hydratase is a NIT4 Homolog , 2006, Plant Molecular Biology.

[51]  J. Nickelsen,et al.  An Intermediate Membrane Subfraction in Cyanobacteria Is Involved in an Assembly Network for Photosystem II Biogenesis* , 2011, The Journal of Biological Chemistry.

[52]  Daniel Karcher,et al.  Generation of Chlamydomonas strains that efficiently express nuclear transgenes. , 2009, The Plant journal : for cell and molecular biology.

[53]  Nandita Sarkar,et al.  Tandem inverted repeat system for selection of effective transgenic RNAi strains in Chlamydomonas. , 2004, The Plant journal : for cell and molecular biology.

[54]  P. Hegemann,et al.  A synthetic gene coding for the green fluorescent protein (GFP) is a versatile reporter in Chlamydomonas reinhardtii. , 1999, The Plant journal : for cell and molecular biology.

[55]  J. Rochaix,et al.  Nuclear mutations specifically affect the synthesis and/or degradation of the chloroplast‐encoded D2 polypeptide of photosystem II in Chlamydomonas reinhardtii , 1988, The EMBO journal.

[56]  W. Zerges,et al.  Chloroplast protein targeting involves localized translation in Chlamydomonas , 2009, Proceedings of the National Academy of Sciences.

[57]  A. Bhardwaj,et al.  A metabolic enzyme doing double duty as a transcription factor. , 2005, BioEssays : news and reviews in molecular, cellular and developmental biology.

[58]  J. Gerst.  RNA Detection and Visualization , 2011, Methods in Molecular Biology.

[59]  M. Schroda,et al.  Sequence elements within an HSP70 promoter counteract transcriptional transgene silencing in Chlamydomonas. , 2002, The Plant journal : for cell and molecular biology.

[60]  W. Zerges,et al.  Biogenic membranes of the chloroplast in Chlamydomonas reinhardtii , 2012, Proceedings of the National Academy of Sciences.

[61]  K. Nicholas,et al.  GeneDoc: Analysis and visualization of genetic variation , 1997 .

[62]  J. Rochaix,et al.  The flanking regions of PsaD drive efficient gene expression in the nucleus of the green alga Chlamydomonas reinhardtii , 2001, Molecular Genetics and Genomics.

[63]  M. Spalding,et al.  Molecular and Structural Changes in Chlamydomonas under Limiting CO2 (A Possible Mitochondrial Role in Adaptation) , 1996, Plant physiology.

[64]  M. Schroda,et al.  The HSP70A promoter as a tool for the improved expression of transgenes in Chlamydomonas. , 2000, The Plant journal : for cell and molecular biology.

[65]  J. Nickelsen,et al.  Initial Steps of Photosystem II de Novo Assembly and Preloading with Manganese Take Place in Biogenesis Centers in Synechocystis[C][W] , 2012, Plant Cell.

[66]  M. Emes,et al.  Pyruvate dehydrogenase complex and acetyl-CoA carboxylase in pea root plastids: their characterization and role in modulating glycolytic carbon flow to fatty acid biosynthesis , 1996 .

[67]  Jae-Hyung Lee,et al.  RNABindR: a server for analyzing and predicting RNA-binding sites in proteins , 2007, Nucleic Acids Res..

[68]  F. Chueh,et al.  Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells. , 2010, Biochemical and biophysical research communications.

[69]  K. Wellen,et al.  A two-way street: reciprocal regulation of metabolism and signalling , 2012, Nature Reviews Molecular Cell Biology.

[70]  S. Lerbs-Mache,et al.  The RNA-binding proteins CSP41a and CSP41b may regulate transcription and translation of chloroplast-encoded RNAs in Arabidopsis , 2009, Plant Molecular Biology.

[71]  Rodrigo Lopez,et al.  Clustal W and Clustal X version 2.0 , 2007, Bioinform..

[72]  L. Ponnala,et al.  Megadalton Complexes in the Chloroplast Stroma of Arabidopsis thaliana Characterized by Size Exclusion Chromatography, Mass Spectrometry, and Hierarchical Clustering* , 2010, Molecular & Cellular Proteomics.

[73]  S. Mayfield,et al.  Processing of the psbA 5′ Untranslated Region in Chlamydomonas reinhardtii Depends upon Factors Mediating Ribosome Association , 1998, The Journal of cell biology.

[74]  L. Reed,et al.  Structure-function relationships in dihydrolipoamide acyltransferases. , 1990, The Journal of biological chemistry.

[75]  B. Mooney,et al.  The complex fate of alpha-ketoacids. , 2002, Annual review of plant biology.

[76]  C. Lyttle,et al.  Pyruvate dehydrogenase complex from higher plant mitochondria and proplastids. , 1977, Plant physiology.

[77]  Elizabeth H. Harris,et al.  The Chlamydomonas Sourcebook: A Comprehensive Guide to Biology and Laboratory Use , 1989 .

[78]  Katherine Kantardjieff,et al.  Identification and characterization of a novel RNA binding protein that associates with the 5'-untranslated region of the chloroplast psbA mRNA. , 2004, Biochemistry.

[79]  D. Randall,et al.  Purification and Characterization of the Pea Chloroplast Pyruvate Dehydrogenase Complex : A Source of Acetyl-CoA and NADH for Fatty Acid Biosynthesis. , 1985, Plant physiology.

[80]  D. Oliver,et al.  Disruption of plE2, the gene for the E2 subunit of the plastid pyruvate dehydrogenase complex, in Arabidopsis causes an early embryo lethal phenotype , 2003, Plant Molecular Biology.

[81]  R. Lightowlers,et al.  Identification of the NAD(+)-binding fold of glyceraldehyde-3-phosphate dehydrogenase as a novel RNA-binding domain. , 2000, Biochemical and biophysical research communications.

[82]  J. Nickelsen,et al.  A chloroplast RNA binding protein from stromal thylakoid membranes specifically binds to the 5' untranslated region of the psbA mRNA. , 2002, European journal of biochemistry.

[83]  W. Belknap.  Partial Purification of Intact Chloroplasts from Chlamydomonas reinhardtii. , 1983, Plant physiology.

[84]  L. Reed,et al.  A Trail of Research from Lipoic Acid to α-Keto Acid Dehydrogenase Complexes , 2001, The Journal of Biological Chemistry.