Use of Classification Regression Tree in Predicting Oral Absorption in Humans
暂无分享,去创建一个
Gordon M. Crippen | Lan Jiang | Volker Fischer | Jane P. F. Bai | Andrey Utis | Han-Dan He | Robert Tullman | He-Qun Yin | Cheng-Pang Hsu | Kin-Kai Hwang | G. Crippen | V. Fischer | Cheng-Pang Hsu | J. Bai | R. Tullman | K. Hwang | H. Yin | Andrey Utis | Han-Dan He | Lan Jiang
[1] Veerabahu Shanmugasundaram,et al. Estimation of Aqueous Solubility of Organic Compounds with QSPR Approach , 2004, Pharmaceutical Research.
[2] G. W. Wheland,et al. Advanced Organic Chemistry , 1951, Nature.
[3] Peter C. Jurs,et al. Prediction of Aqueous Solubility of Heteroatom‐Containing Organic Compounds from Molecular Structure. , 2001 .
[4] G. Amidon,et al. Gastrointestinal Transport of Peptide and Protein Drugs and Prodrugs , 1994 .
[5] Gordon M. Crippen,et al. Prediction of Physicochemical Parameters by Atomic Contributions , 1999, J. Chem. Inf. Comput. Sci..
[6] Kin-Kai Hwang,et al. A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential. , 2002, European journal of medicinal chemistry.
[7] M. Hümpel,et al. Pharmacokinetics of proterguride in rat and cynomolgus monkey. , 1988, Xenobiotica; the fate of foreign compounds in biological systems.
[8] A. Doherty,et al. Structure-activity relationships in a series of orally active gamma-hydroxy butenolide endothelin antagonists. , 1997, Journal of medicinal chemistry.
[9] A. Molla,et al. Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy. , 1998, Journal of medicinal chemistry.
[10] E. Roth,et al. Predicting stroke inpatient rehabilitation outcome using a classification tree approach. , 1994, Archives of physical medicine and rehabilitation.
[11] G. Amidon,et al. Characterization of the Oral Absorption of β-Lactam Antibiotics. I. Cephalosporins: Determination of Intrinsic Membrane Absorption Parameters in the Rat Intestine In Situ , 1988, Pharmaceutical Research.
[12] H. Kim,et al. Dose-dependent pharmacokinetics of a new neuroprotective agent for ischemia-reperfusion damage, KR-31378, in rats. , 2000, Biopharmaceutics & drug disposition.
[13] Ismael J. Hidalgo,et al. The Role of an α‐Amino Group on H+‐dependent Transepithelial Transport of Cephalosporins in Caco‐2 Cells , 1999 .
[14] J. Mair,et al. A decision tree for the early diagnosis of acute myocardial infarction in nontraumatic chest pain patients at hospital admission. , 1995, Chest.
[15] R. Dixon,et al. Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-A selective antagonist. , 1997, Journal of Medicinal Chemistry.
[16] R. Conradi,et al. The relationship between peptide structure and transport across epithelial cell monolayers , 1992 .
[17] P. Selzer,et al. Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. , 2000, Journal of medicinal chemistry.
[18] John Bradshaw,et al. Identification of Biological Activity Profiles Using Substructural Analysis and Genetic Algorithms , 1998, J. Chem. Inf. Comput. Sci..
[19] Shaomeng Wang,et al. Estimation of aqueous solubility of organic molecules by the group contribution approach. Application to the study of biodegradation , 1992, J. Chem. Inf. Comput. Sci..
[20] F. Lombardo,et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. , 2001, Advanced drug delivery reviews.
[21] M. Merino Sanjuán,et al. Intestinal transport of cefuroxime axetil in rats: absorption and hydrolysis processes. , 2002, International journal of pharmaceutics.
[22] P. Gros,et al. Lipophilic cations: a group of model substrates for the multidrug-resistance transporter. , 1992, Biochemistry.
[23] H. van de Waterbeemd,et al. Property-based design: optimization of drug absorption and pharmacokinetics. , 2001, Journal of medicinal chemistry.
[24] G. Amidon,et al. Passive and Carrier-Mediated Intestinal Absorption Components of Two Angiotensin Converting Enzyme (ACE) Inhibitor Prodrugs in Rats: Enalapril and Fosinopril , 1989, Pharmaceutical Research.
[25] J. Ross Quinlan,et al. Induction of Decision Trees , 1986, Machine Learning.
[26] Luhua Lai,et al. A New Atom-Additive Method for Calculating Partition Coefficients , 1997, J. Chem. Inf. Comput. Sci..