Cytokinetic abscission: cellular dynamics at the midbody.

[1]  Mullins Jm,et al.  Terminal phase of cytokinesis in D-98S cells , 1977 .

[2]  S. Blose,et al.  Passage of molecules across the intercellular bridge between post-mitotic daughter cells. , 1984, Experimental cell research.

[3]  G. Piperno,et al.  Microtubules containing acetylated alpha-tubulin in mammalian cells in culture , 1987, The Journal of cell biology.

[4]  H. Mazarguil,et al.  gamma-Tubulin participates in the formation of the midbody during cytokinesis in mammalian cells. , 1993, Journal of cell science.

[5]  A. Ciechanover,et al.  Nuclear localization of the ubiquitin-activating enzyme, E1, is cell-cycle-dependent. , 1994, The Biochemical journal.

[6]  Stuart Tugendreich,et al.  CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition , 1995, Cell.

[7]  Q. Li,et al.  A transient association of gamma-tubulin at the midbody is required for the completion of cytokinesis during the mammalian cell division. , 1995, Journal of cell science.

[8]  C. Wójcik,et al.  Localization of proteasomal antigens during different phases of the cell cycle in HeLa cells. , 1995, European journal of cell biology.

[9]  I. Yahara,et al.  Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[10]  C. Rieder,et al.  Long crocidolite asbestos fibers cause polyploidy by sterically blocking cytokinesis. , 1996, Carcinogenesis.

[11]  Robert Presley,et al.  Evolutionary biology: Pelvic problems for mammals , 1997, Nature.

[12]  Jennifer Lippincott-Schwartz,et al.  ER-to-Golgi transport visualized in living cells , 1997, Nature.

[13]  D. L. Taylor,et al.  Traction forces of cytokinesis measured with optically modified elastic substrata , 1997, Nature.

[14]  D. Knecht,et al.  Use of a fusion protein between GFP and an actin-binding domain to visualize transient filamentous-actin structures , 1998, Current Biology.

[15]  E. Salmon,et al.  E-MAP-115 (ensconsin) associates dynamically with microtubules in vivo and is not a physiological modulator of microtubule dynamics. , 1999, Journal of cell science.

[16]  M. Watson,et al.  INHIBITION OF CYTOKINESIS BY ASBESTOS AND SYNTHETIC FIBRES , 1999, Cell biology international.

[17]  M. Danilchik,et al.  Microtubules are required for completion of cytokinesis in sea urchin eggs. , 1999, Developmental biology.

[18]  T. Miki,et al.  Human Ect2 Is an Exchange Factor for Rho Gtpases, Phosphorylated in G2/M Phases, and Involved in Cytokinesis , 1999, The Journal of cell biology.

[19]  D. Stephens,et al.  Lumenal targeted GFP, used as a marker of soluble cargo, visualises rapid ERGIC to Golgi traffic by a tubulo-vesicular network. , 2000, Journal of cell science.

[20]  Kazuo Emoto,et al.  An Essential Role for a Membrane Lipid in Cytokinesis , 2000, The Journal of cell biology.

[21]  Peter G. Schultz,et al.  A chemical switch for inhibitor-sensitive alleles of any protein kinase , 2000, Nature.

[22]  Kai Simons,et al.  Multicolour imaging of post-Golgi sorting and trafficking in live cells , 2001, Nature Cell Biology.

[23]  John White,et al.  Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive membrane accumulation at the cleavage furrow apex , 2001, Current Biology.

[24]  M. Bornens,et al.  Centrosome-Dependent Exit of Cytokinesis in Animal Cells , 2001, Science.

[25]  J. Matulienė,et al.  Kinesin-like protein CHO1 is required for the formation of midbody matrix and the completion of cytokinesis in mammalian cells. , 2002, Molecular biology of the cell.

[26]  Yu-Li Wang,et al.  Probing the dynamics and functions of aurora B kinase in living cells during mitosis and cytokinesis. , 2002, Molecular biology of the cell.

[27]  R. Tsien,et al.  Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells , 2002, Science.

[28]  George H. Patterson,et al.  A Photoactivatable GFP for Selective Photolabeling of Proteins and Cells , 2002, Science.

[29]  T. Hunter,et al.  PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone , 2002, The Journal of cell biology.

[30]  Y. Terada,et al.  CHO1, a mammalian kinesin-like protein, interacts with F-actin and is involved in the terminal phase of cytokinesis , 2002, The Journal of cell biology.

[31]  M. Glotzer,et al.  Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity. , 2002, Developmental cell.

[32]  George H Patterson,et al.  Photobleaching and photoactivation: following protein dynamics in living cells. , 2003, Nature cell biology.

[33]  Niels Galjart,et al.  Visualization of Microtubule Growth in Cultured Neurons via the Use of EB3-GFP (End-Binding Protein 3-Green Fluorescent Protein) , 2003, The Journal of Neuroscience.

[34]  Timothy J Mitchison,et al.  Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor , 2003, Science.

[35]  T. Weimbs,et al.  Syntaxin 2 and endobrevin are required for the terminal step of cytokinesis in mammalian cells. , 2003, Developmental cell.

[36]  R. Saint,et al.  A RhoGEF and Rho family GTPase-activating protein complex links the contractile ring to cortical microtubules at the onset of cytokinesis. , 2003, Developmental cell.

[37]  Roger Y Tsien,et al.  Genetically targeted chromophore-assisted light inactivation , 2003, Nature Biotechnology.

[38]  P. O’Farrell,et al.  The Degradation of Two Mitotic Cyclins Contributes to the Timing of Cytokinesis , 2003, Current Biology.

[39]  Karl Mechtler,et al.  Mitotic regulation of the human anaphase‐promoting complex by phosphorylation , 2003, The EMBO journal.

[40]  Norbert Perrimon,et al.  Parallel Chemical Genetic and Genome-Wide RNAi Screens Identify Cytokinesis Inhibitors and Targets , 2004, PLoS biology.

[41]  J. Yates,et al.  Dissection of the Mammalian Midbody Proteome Reveals Conserved Cytokinesis Mechanisms , 2004, Science.

[42]  J. Sanger,et al.  Midbody sealing after cytokinesis in embryos of the sea urchin Arabacia punctulata , 2004, Cell and Tissue Research.

[43]  K. Kamijo,et al.  Deregulation and Mislocalization of the Cytokinesis Regulator ECT2 Activate the Rho Signaling Pathways Leading to Malignant Transformation* , 2004, Journal of Biological Chemistry.

[44]  Yves Barral,et al.  Spatial Coordination of Cytokinetic Events by Compartmentalization of the Cell Cortex , 2004, Science.

[45]  B. Nichols,et al.  A Barrier to Lateral Diffusion in the Cleavage Furrow of Dividing Mammalian Cells , 2004, Current Biology.

[46]  J. Pines,et al.  Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells , 2004, The Journal of cell biology.

[47]  P. O’Farrell,et al.  Terminal Cytokinesis Events Uncovered after an RNAi Screen , 2004, Current Biology.

[48]  J. Matulienė,et al.  Role of the midbody matrix in cytokinesis: RNAi and genetic rescue analysis of the mammalian motor protein CHO1. , 2004, Molecular biology of the cell.

[49]  E. Nigg,et al.  Cell cycle regulation of central spindle assembly , 2004, Nature.

[50]  C. D’Souza-Schorey,et al.  Finishing the job: cytoskeletal and membrane events bring cytokinesis to an end. , 2004, Experimental cell research.

[51]  G. Fang,et al.  Anillin Is a Substrate of Anaphase-promoting Complex/Cyclosome (APC/C) That Controls Spatial Contractility of Myosin during Late Cytokinesis*[boxs] , 2005, Journal of Biological Chemistry.

[52]  David Pellman,et al.  Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells , 2005, Nature.

[53]  H. Benink,et al.  Concentric zones of active RhoA and Cdc42 around single cell wounds , 2005, The Journal of cell biology.

[54]  M. Glotzer,et al.  Phosphorylation of ZEN-4/MKLP1 by Aurora B Regulates Completion of Cytokinesis , 2005, Current Biology.

[55]  Hao G. Nguyen,et al.  Mechanism of Aurora-B Degradation and Its Dependency on Intact KEN and A-Boxes: Identification of an Aneuploidy-Promoting Property , 2005, Molecular and Cellular Biology.

[56]  S. Narumiya,et al.  Local Change in Phospholipid Composition at the Cleavage Furrow Is Essential for Completion of Cytokinesis* , 2005, Journal of Biological Chemistry.

[57]  Klaus Aktories,et al.  Bacterial cytotoxins: targeting eukaryotic switches , 2005, Nature Reviews Microbiology.

[58]  M. Glotzer,et al.  An ECT2–centralspindlin complex regulates the localization and function of RhoA , 2005, The Journal of cell biology.

[59]  C. Mandato,et al.  Wound-induced contractile ring: a model for cytokinesis. , 2005, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[60]  C. Sanderson,et al.  The hereditary spastic paraplegia protein spastin interacts with the ESCRT-III complex-associated endosomal protein CHMP1B. , 2005, Human molecular genetics.

[61]  G. Polevoy,et al.  PIP2 Hydrolysis and Calcium Release Are Required for Cytokinesis in Drosophila Spermatocytes , 2005, Current Biology.

[62]  S. Baldwin,et al.  Rab11‐FIP3 and FIP4 interact with Arf6 and the Exocyst to control membrane traffic in cytokinesis , 2005, The EMBO journal.

[63]  A. Straight,et al.  Anillin binds nonmuscle myosin II and regulates the contractile ring. , 2004, Molecular biology of the cell.

[64]  L. Cantley,et al.  PtdIns(4,5)P2 Functions at the Cleavage Furrow during Cytokinesis , 2005, Current Biology.

[65]  Glenn C. Simon,et al.  The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis. , 2004, Molecular biology of the cell.

[66]  K. Oegema,et al.  Distinct roles for two C. elegans anillins in the gonad and early embryo , 2005, Development.

[67]  S. Stewart,et al.  Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1. , 2005, Cancer research.

[68]  S. Redick,et al.  Centriolin Anchoring of Exocyst and SNARE Complexes at the Midbody Is Required for Secretory-Vesicle-Mediated Abscission , 2005, Cell.

[69]  M. Glotzer,et al.  The Molecular Requirements for Cytokinesis , 2005, Science.

[70]  R. Schwarzenbacher,et al.  Spatiotemporal control of spindle midzone formation by PRC1 in human cells. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[71]  J. Lippincott-Schwartz,et al.  Imaging Intracellular Fluorescent Proteins at Nanometer Resolution , 2006, Science.

[72]  Timothy J Mitchison,et al.  Animal cytokinesis: from parts list to mechanisms. , 2006, Annual review of biochemistry.

[73]  K. Hahn,et al.  Spatiotemporal dynamics of RhoA activity in migrating cells , 2006, Nature.

[74]  Yves Barral,et al.  The NoCut Pathway Links Completion of Cytokinesis to Spindle Midzone Function to Prevent Chromosome Breakage , 2006, Cell.

[75]  G. Fang,et al.  Cep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesis. , 2006, Molecular biology of the cell.

[76]  Timothy J Mitchison,et al.  Small molecule screening by imaging. , 2006, Current opinion in chemical biology.

[77]  R. Tsien,et al.  Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy , 2006, Proceedings of the National Academy of Sciences.

[78]  D. Altieri,et al.  Survivin modulates microtubule dynamics and nucleation throughout the cell cycle. , 2005, Molecular biology of the cell.

[79]  E. Nigg,et al.  Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission , 2006, Journal of Cell Science.

[80]  U. Klein,et al.  Cooperation between Mitotic Kinesins Controls the Late Stages of Cytokinesis , 2006, Current Biology.

[81]  Konstantin A Lukyanov,et al.  Chromophore-assisted light inactivation (CALI) using the phototoxic fluorescent protein KillerRed , 2006, Nature Protocols.

[82]  S. Yonemura,et al.  Centralspindlin regulates ECT2 and RhoA accumulation at the equatorial cortex during cytokinesis , 2006, Journal of Cell Science.

[83]  S. Hell,et al.  STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis , 2006, Nature.

[84]  C. Mandato,et al.  Regulation of the actin cytoskeleton by PIP2 in cytokinesis , 2006, Biology of the cell.

[85]  B. Goud,et al.  Rab35 Regulates an Endocytic Recycling Pathway Essential for the Terminal Steps of Cytokinesis , 2006, Current Biology.

[86]  P. Devreotes,et al.  Phosphoinositide signaling plays a key role in cytokinesis , 2006, The Journal of cell biology.

[87]  Erich A. Nigg,et al.  KIF14 and citron kinase act together to promote efficient cytokinesis , 2006, The Journal of cell biology.

[88]  K. Kamijo,et al.  Dissecting the role of Rho-mediated signaling in contractile ring formation. , 2005, Molecular biology of the cell.

[89]  Neil J Ganem,et al.  Tetraploidy, aneuploidy and cancer. , 2007, Current opinion in genetics & development.

[90]  E. Nigg,et al.  Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis. , 2007, Molecular biology of the cell.

[91]  S. Munro,et al.  The small G proteins of the Arf family and their regulators. , 2007, Annual review of cell and developmental biology.

[92]  T. Kirchhausen,et al.  Endosomal recycling controls plasma membrane area during mitosis , 2007, Proceedings of the National Academy of Sciences.

[93]  A. Hall,et al.  Rho GTPases regulate PRK2/PKN2 to control entry into mitosis and exit from cytokinesis , 2007, The EMBO journal.

[94]  A. Hyman,et al.  Genome-scale RNAi profiling of cell division in human tissue culture cells , 2007, Nature Cell Biology.

[95]  Jan-Michael Peters,et al.  Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. , 2007, Developmental cell.

[96]  F. Barr,et al.  Cytokinesis: Placing and Making the Final Cut , 2007, Cell.

[97]  J. Peters,et al.  The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1 , 2007, Current Biology.

[98]  J. Martin-Serrano,et al.  Parallels Between Cytokinesis and Retroviral Budding: A Role for the ESCRT Machinery , 2007, Science.

[99]  GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. , 2007, Developmental cell.

[100]  G. Gould,et al.  Role of endosomal Rab GTPases in cytokinesis. , 2007, European journal of cell biology.

[101]  S. Gygi,et al.  Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis , 2007, The EMBO journal.

[102]  Chunyong Liu,et al.  EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A , 2008, Proceedings of the National Academy of Sciences.

[103]  Stephen S. Taylor,et al.  Polo and Aurora kinases: lessons derived from chemical biology. , 2008, Current opinion in cell biology.

[104]  Natalie Elia,et al.  Midbody Targeting of the ESCRT Machinery by a Noncanonical Coiled Coil in CEP55 , 2008, Science.

[105]  D. Brautigan,et al.  Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells. , 2008, Molecular biology of the cell.

[106]  Michael J. Emanuele,et al.  Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly , 2008, The Journal of cell biology.

[107]  J. Lippincott-Schwartz,et al.  Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B , 2008, Nature Structural &Molecular Biology.

[108]  Stephen S. Taylor,et al.  Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery , 2008, Nature.

[109]  Christian Pohl,et al.  Final Stages of Cytokinesis and Midbody Ring Formation Are Controlled by BRUCE , 2008, Cell.

[110]  M. Gustafsson,et al.  Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy , 2008, Science.

[111]  Eric A. Vitriol,et al.  Chromophore-assisted laser inactivation in cell biology. , 2008, Trends in cell biology.

[112]  J. Martin-Serrano,et al.  Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release , 2008, Proceedings of the National Academy of Sciences.

[113]  A. Echard Membrane traffic and polarization of lipid domains during cytokinesis. , 2008, Biochemical Society transactions.

[114]  P. Chavrier,et al.  Endocytic traffic in animal cell cytokinesis. , 2008, Current opinion in cell biology.

[115]  David L. Brautigan,et al.  Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient , 2008, Nature.

[116]  D. Toomre,et al.  Both daughter cells traffic and exocytose membrane at the cleavage furrow during mammalian cytokinesis , 2008, The Journal of cell biology.

[117]  P. O’Farrell,et al.  Rho-dependent control of anillin behavior during cytokinesis , 2008, The Journal of cell biology.

[118]  P. Hanson,et al.  Plasma membrane deformation by circular arrays of ESCRT-III protein filaments , 2008, The Journal of cell biology.

[119]  P. O’Farrell,et al.  Anillin: a pivotal organizer of the cytokinetic machinery. , 2008, Biochemical Society transactions.

[120]  T. Holak,et al.  Lifeact: a versatile marker to visualize F-actin , 2008, Nature Methods.

[121]  A. Faisal,et al.  The regulated assembly of a PKCɛ complex controls the completion of cytokinesis , 2008, Nature Cell Biology.

[122]  V. Foe,et al.  Stable and dynamic microtubules coordinately shape the myosin activation zone during cytokinetic furrow formation , 2008, The Journal of cell biology.

[123]  James R Bischoff,et al.  CDK inhibitors in cancer therapy: what is next? , 2008, Trends in pharmacological sciences.

[124]  J. Pines,et al.  APC/CCdh1 Targets Aurora Kinase to Control Reorganization of the Mitotic Spindle at Anaphase , 2008, Current Biology.

[125]  Jacob Piehler,et al.  Helical Structures of ESCRT-III Are Disassembled by VPS4 , 2008, Science.

[126]  Glenn C. Simon,et al.  Sequential Cyk‐4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis , 2008, The EMBO journal.

[127]  Stefan W. Hell,et al.  Supporting Online Material Materials and Methods Figs. S1 to S9 Tables S1 and S2 References Video-rate Far-field Optical Nanoscopy Dissects Synaptic Vesicle Movement , 2022 .

[128]  M. Komada,et al.  Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis , 2008, Journal of Cell Science.

[129]  M. Glotzer,et al.  Anillin Is a Scaffold Protein That Links RhoA, Actin, and Myosin during Cytokinesis , 2008, Current Biology.

[130]  Wei Zhang,et al.  Interaction between Anillin and RacGAP50C connects the actomyosin contractile ring with spindle microtubules at the cell division site , 2008, Journal of Cell Science.

[131]  Alexey Khodjakov,et al.  Extra centrosomes and/or chromosomes prolong mitosis in human cells , 2008, Nature Cell Biology.

[132]  J. Sibarita,et al.  ARF6 Interacts with JIP4 to Control a Motor Switch Mechanism Regulating Endosome Traffic in Cytokinesis , 2009, Current Biology.

[133]  Stefan Hümmer,et al.  Cdk1 Negatively Regulates Midzone Localization of the Mitotic Kinesin Mklp2 and the Chromosomal Passenger Complex , 2009, Current Biology.

[134]  O. Medalia,et al.  Profilin 1 is required for abscission during late cytokinesis of chondrocytes , 2009, The EMBO journal.

[135]  D. Gerlich,et al.  Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization , 2009, Cell.

[136]  M. Glotzer,et al.  The 3Ms of central spindle assembly: microtubules, motors and MAPs , 2009, Nature Reviews Molecular Cell Biology.

[137]  Ann L. Miller,et al.  Regulation of cytokinesis by Rho GTPase flux , 2008, Nature Cell Biology.

[138]  J. Luzio,et al.  Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion , 2008, Traffic.

[139]  J. Lippincott-Schwartz,et al.  Interferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure , 2009, Proceedings of the National Academy of Sciences.

[140]  S. Ameer-Beg,et al.  Essential role of hIST1 in cytokinesis. , 2009, Molecular biology of the cell.

[141]  J. Ellenberg,et al.  Chromophore-assisted laser inactivation of alpha- and gamma-tubulin SNAP-tag fusion proteins inside living cells. , 2009, ACS chemical biology.

[142]  Jennifer Lippincott-Schwartz,et al.  Membrane scission by the ESCRT-III complex , 2009, Nature.

[143]  Christian Pohl,et al.  Midbody ring disposal by autophagy is a post-abscission event of cytokinesis , 2009, Nature Cell Biology.

[144]  C. Norden,et al.  A mechanism for chromosome segregation sensing by the NoCut checkpoint , 2009, Nature Cell Biology.

[145]  D. Gerlich,et al.  An evolutionary conserved checkpoint controls abscission timing , 2009, Cell cycle.

[146]  P. Várnai,et al.  Visualization of Cellular Phosphoinositide Pools with GFP‐Fused Protein‐Domains , 2009, Current protocols in cell biology.

[147]  Harald Stenmark,et al.  The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins , 2009, Nature.

[148]  W. Sundquist,et al.  Biochemical analyses of human IST1 and its function in cytokinesis. , 2009, Molecular biology of the cell.

[149]  S. Emr,et al.  Functional Reconstitution of ESCRT-III Assembly and Disassembly , 2009, Cell.

[150]  David O. Morgan,et al.  The Cell Cycle: Principles of Control , 2014 .