A new influenza surveillance system in France: The Ile-De-France “GROG”. I. Principles and methodology

The aims of influenza surveillance have changed over the years. The early detection of epidemics is essential for practical decisions on vaccine development, strategy of vaccine prophylaxis, chemoprophylaxis or chemotherapy. A new surveillance system is presented which combines the classical specific data related to the isolations, direct detection of virus as well as serological findings, with non-specific indices. The rationale for definition and elaboration of such indices is discussed: selected parameters deal with medical activity of a panel of sentinel doctors (general practitioners and pediatricians), notifications of diagnosed acute respiratory viral infections, measure of emergency doctors activity, absence from work (as seen by physicians, insurance agencies or industrial personnel), selected drug prescription and consumption, hospital admissions. The sentinel physicians also cooperate in taking samples from cases, thereby extending the field of specific surveillance since they have contact with standard cases of the disease and not only hospitalized patients. A weekly comparison of time variations of specific and non-specific indices should permit a reliable evaluation of the epidemic situation and therefore be of great help for practical decisions. The system has operated since 1984, and the initial hypothesis of the sensitivity of some of the indices has already been verified.

[1]  S B Thacker,et al.  An evaluation of influenza mortality surveillance, 1962-1979. I. Time series forecasts of expected pneumonia and influenza deaths. , 1981, American journal of epidemiology.

[2]  W. P. Glezen,et al.  Serious morbidity and mortality associated with influenza epidemics. , 1982, Epidemiologic reviews.

[3]  J. Hampton,et al.  PREVALENCE OF ANGINA AS ASSESSED BY A SURVEY OF PRESCRIPTIONS FOR NITRATES , 1988, The Lancet.

[4]  Glezen Wp,et al.  SERIOUS MORBIDITY AND MORTALITY ASSOCIATED WITH INFLUENZA EPIDEMICS , 1982 .

[5]  C. Stuart-harris,et al.  Epidemiology of influenza in man. , 1979, British medical bulletin.

[6]  R. Douglas,et al.  Respiratory syncytial virus and influenza. Practical community surveillance. , 1976, American journal of diseases of children.

[7]  R. Serfling,et al.  Observations on excess mortality associated with epidemic influenza. , 1961, Maryland state medical journal.

[8]  R. Vogt,et al.  Comparison of an active and passive surveillance system of primary care providers for hepatitis, measles, rubella, and salmonellosis in Vermont. , 1983, American journal of public health.

[9]  A. Kendal,et al.  Economical laboratory support system for influenza virus surveillance , 1987, Journal of clinical microbiology.

[10]  A. Langmuir,et al.  Excess mortality from epidemic influenza, 1957-1966. , 1974, American journal of epidemiology.

[11]  J. Mcgowan,et al.  Influenza detection: a prospective comparison of surveillance methods and analysis of isolates. , 1976, American journal of epidemiology.

[12]  W. Barker,et al.  Excess pneumonia and influenza associated hospitalization during influenza epidemics in the United States, 1970-78. , 1986, American journal of public health.

[13]  R. Reichman,et al.  A controlled trial of amantadine and rimantadine in the prophylaxis of influenza A infection. , 1982, The New England journal of medicine.

[14]  L P Smith.  Numerical forecasting of epidemics of influenza in Great Britain and Northern Ireland. , 1982, Revue d'epidemiologie et de sante publique.

[15]  J. Fox,et al.  Influenza surveillance in the Pacific Northwest 1976-1980. , 1983, International journal of epidemiology.

[16]  D M Perrotta,et al.  Acute respiratory disease hospitalizations as a measure of impact of epidemic influenza. , 1985, American journal of epidemiology.

[17]  S. Thacker,et al.  The surveillance of infectious diseases. , 1983, JAMA.

[18]  S B Thacker,et al.  A controlled trial of disease surveillance strategies. , 1986, American journal of preventive medicine.

[19]  A. Valleron,et al.  A computer network for the surveillance of communicable diseases: the French experiment. , 1986, American journal of public health.

[20]  D. Fleming,et al.  Diagnosis and patterns of incidence of influenza, influenza-like illness and the common cold in general practice. , 1988, The Journal of the Royal College of General Practitioners.

[21]  U Helfenstein,et al.  Box-Jenkins modelling of some viral infectious diseases. , 1986, Statistics in medicine.

[22]  S B Thacker,et al.  A method for evaluating systems of epidemiological surveillance. , 1988, World health statistics quarterly. Rapport trimestriel de statistiques sanitaires mondiales.

[23]  R. Serfling.  Methods for current statistical analysis of excess pneumonia-influenza deaths. , 1963, Public health reports.

[24]  A D LANGMUIR,et al.  The surveillance of communicable diseases of national importance. , 1963, The New England journal of medicine.

[25]  S. Thacker,et al.  From the centers for disease control. Improved accuracy and specificity of forecasting deaths attributed to pneumonia and influenza. , 1981, The Journal of infectious diseases.

[26]  A. Kendal,et al.  Impact of influenza epidemics on mortality in the United States from October 1972 to May 1985. , 1987, American journal of public health.

[27]  K. Goh,et al.  Influenza surveillance in Singapore: 1972-86. , 1988, Bulletin of the World Health Organization.

[28]  R. Couch,et al.  The influenza herald wave. , 1982, American journal of epidemiology.

[29]  S B Thacker,et al.  An evaluation of influenza mortality surveillance, 1962-1979. II. Percentage of pneumonia and influenza deaths as an indicator of influenza activity. , 1981, American journal of epidemiology.

[30]  V. van Casteren,et al.  Tool for validation of the network of sentinel general practitioners in the Belgian health care system. , 1987, International journal of epidemiology.

[31]  R. Marier,et al.  The reporting of communicable diseases. , 1977, American journal of epidemiology.

[32]  Smith Lp.  Numerical forecasting of epidemics of influenza in Great Britain and Northern Ireland. , 1982 .

[33]  L. Irwig.  Surveillance in developed countries with particular reference to child growth. , 1976, International journal of epidemiology.