RNAprobR: An R package for analysis of the massive parallel sequencing based methods of RNA structure probing
暂无分享,去创建一个
RNA structure probing is more and more often conducted with the use of high-throughput sequencing. Analysis of data coming from those experiments can be challenging and time consuming. Here we describe an R package RNAprobR which intends to standardize and simplify processing of experiments for which information on RNA susceptibility to different probing conditions is encoded in a location of sequenced reads termini.
[1] Lukasz Jan Kielpinski,et al. Massive parallel-sequencing-based hydroxyl radical probing of RNA accessibility , 2014, Nucleic acids research.
[2] A. Nekrutenko,et al. Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences , 2010, Genome Biology.
[3] S. P. Fodor,et al. Counting individual DNA molecules by the stochastic attachment of diverse labels , 2011, Proceedings of the National Academy of Sciences.